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of 8
pro vyhledávání: '"Phillipa White"'
Autor:
Helen J. Wright, Michael R. Milward, Paul R. Cooper, Iain L. C. Chapple, Josefine Hirschfeld, John B. Matthews, Phillipa White
Publikováno v:
Journal of Periodontal Research. 53:525-535
BACKGROUND AND OBJECTIVE Cigarette smoking is a major risk factor for periodontitis, and smoking perturbs neutrophil reactive oxygen species production. This study tested the hypothesis that cigarette smoke extract (CSE) and its components/metabolite
Publikováno v:
Infection and immunity. 85(12)
Oral bacteria are the main trigger for the development of periodontitis, and some species are known to modulate neutrophil function. This study aimed to explore the release of neutrophil extracellular traps (NETs), associated antimicrobial proteins,
Autor:
Paul R. Cooper, Helen J. Wright, Phillipa White, Martin R. Ling, Ilaria J. Chicca, Michael R. Milward, Iain L. C. Chapple
Publikováno v:
Methods in Molecular Biology ISBN: 9781493966837
Following the discovery of neutrophil extracellular traps (NETs) in 2004 by Brinkmann and colleagues, there has been extensive research into the role of NETs in a number of inflammatory diseases, including periodontitis. This chapter describes the cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19a5d1f982963aa78819d24e903c5b18
https://doi.org/10.1007/978-1-4939-6685-1_29
https://doi.org/10.1007/978-1-4939-6685-1_29
Autor:
Helen Roberts, Martin R. Ling, Iain L. C. Chapple, Paul R. Cooper, Phillipa White, Dimitri Sakellari, Idyli Risafi, Michael R. Milward
Publikováno v:
Journal of clinical periodontology. 43(12)
Aims To investigate ex vivo peripheral neutrophil extracellular trap (NET) production and their subsequent degradation by plasma in chronic periodontitis patients, and periodontally and systemically healthy-matched controls. Materials and methods Chr
Autor:
Helen Roberts, Irundika H.K. Dias, Ratna Veeramachaneni, Iain L. C. Chapple, Phillipa White, Sarah J. McKaig, Melissa M. Grant, Nalin Thakker
Publikováno v:
Journal of leukocyte biology. 100(2)
Papillon-Lefévre syndrome is a rare, inherited, autosomal-recessive disease, characterized by palmoplantar keratosis and severe prepubertal periodontitis, leading to premature loss of all teeth. Papillon-Lefévre syndrome is caused by a mutation in
Publikováno v:
Journal of dental research. 95(1)
Neutrophil extracellular traps (NETs) represent a novel paradigm in neutrophil-mediated immunity. NETs are believed to constitute a highly conserved antimicrobial strategy comprising decondensed nuclear DNA and associated histones that are extruded i
Publikováno v:
Free Radical Biology and Medicine. 75:S53
Periodontitis is a chronic inflammatory disease initiated by periodontal pathogens. Neutrophils play a pivotal role within the periodontal lesion, where they have a cytotoxic arsenal at their disposal, including Reactive oxygen species (ROS) and rele
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