Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Phillip Wibisono"'
Autor:
Phillip Wibisono, Jingru Sun
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
How pathogen infection in a parental generation affects response in future generations to the same pathogen via epigenetic modifications has been the topic of recent studies. These studies focused on changes attributed to transgenerational epigenetic
Externí odkaz:
https://doaj.org/article/9580ce416c9f4f58954a49a7750eca2f
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Caenorhabditis elegans is an excellent research model whose populations have been used in many studies to address various biological questions. Although worm-to-worm phenotypic variations in isogenic populations have been persiste
Externí odkaz:
https://doaj.org/article/cb16a3aba66d44048811d6e5c9271b50
Autor:
Phillip Wibisono, Jingru Sun
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101558- (2022)
Summary: The nematode Caenorhabditis elegans is a common model organism for studies in immunity and host-pathogen interactions. In this protocol, we describe techniques for measuring pharyngeal pumping and defecation rates of adult C. elegans exposed
Externí odkaz:
https://doaj.org/article/10f0d5210b4b4fe6865b67b0f2fe6658
Autor:
Phillip Wibisono, Jingru Sun
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 60-65 (2021)
The innate immune system is a complex collection of physical barriers and physiological defense responses to internal and external environmental assaults. Recent studies in the model organism Caenorhabditis elegans have highlighted how the nervous sy
Externí odkaz:
https://doaj.org/article/b1fd335047414a78b067ecad6211a553
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Caenorhabditis elegans is an excellent model organism for biological research, but its contributions to biochemical elucidation of eukaryotic transcription mechanisms have been limited. One of the biggest obstacles for C. elegans
Externí odkaz:
https://doaj.org/article/0c9a58e90d2940759789fc86eff52e23
Autor:
Phillip Wibisono, Shawndra Wibisono, Jan Watteyne, Chia-Hui Chen, Durai Sellegounder, Isabel Beets, Yiyong Liu, Jingru Sun
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110321- (2022)
Summary: A key question in current immunology is how the innate immune system generates high levels of specificity. Using the Caenorhabditis elegans model system, we demonstrate that functional loss of NMUR-1, a neuronal G-protein-coupled receptor ho
Externí odkaz:
https://doaj.org/article/7e462325263046ce9ef0c03235fb3360
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Upon pathogen infection, the nervous system regulates innate immunity to confer coordinated protection to the host. However, the precise mechanisms of such regulation remain unclear. Previous studies have demonstrated that OCTR-1, a putative
Externí odkaz:
https://doaj.org/article/8aee613a45094d15884ab324fbc9c51d
Publikováno v:
Aging Cell. 22
Autor:
Jingru Sun, Phillip Wibisono
Publikováno v:
Journal of Visualized Experiments.
Caenorhabditis elegans has been an important model system for biological research since it was introduced in 1963. However, C. elegans has not been fully utilized in the biochemical study of biological reactions using its nuclear extracts such as in
We have previously demonstrated that OCTR-1, an octopamine G protein-couple receptor, functions in the sensory neurons ASH to suppress the innate immune response in Caenorhabditis elegans by inhibiting the expression of immune genes (Sun et al. 2011
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aec9d71f2a8fc92898f1b375d47cd802
https://doi.org/10.1101/2021.05.07.443056
https://doi.org/10.1101/2021.05.07.443056