Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Phillip Tremblay"'
1
Akademický článek
Evaluation of the efficacy & biochemical mechanism of cell death induction by Piper longum extract selectively in in-vitro and in-vivo models of human cancer cells.
Autor: Pamela Ovadje, Dennis Ma, Phillip Tremblay, Alessia Roma, Matthew Steckle, Jose-Antonio Guerrero, John Thor Arnason, Siyaram Pandey
Publikováno v: PLoS ONE, Vol 9, Iss 11, p e113250 (2014)
BACKGROUND:Currently chemotherapy is limited mostly to genotoxic drugs that are associated with severe side effects due to non-selective targeting of normal tissue. Natural products play a significant role in the development of most chemotherapeutic
Externí odkaz: https://doaj.org/article/7418ae0815cc495ba6031852955f777a
Zobrazit plný text záznamu
2
Akademický článek
Selective cytotoxicity against human osteosarcoma cells by a novel synthetic C-1 analogue of 7-deoxypancratistatin is potentiated by curcumin.
Autor: Dennis Ma, Phillip Tremblay, Kevinjeet Mahngar, Jonathan Collins, Tomas Hudlicky, Siyaram Pandey
Publikováno v: PLoS ONE, Vol 6, Iss 12, p e28780 (2011)
The natural compound pancratistatin (PST) is a non-genotoxic inducer of apoptosis in a variety of cancers. It exhibits cancer selectivity as non-cancerous cells are markedly less sensitive to PST. Nonetheless, PST is not readily synthesized and is pr
Externí odkaz: https://doaj.org/article/57b064017d7c4bc09912aee1792194ed
Zobrazit plný text záznamu
3
Induction of Apoptosis and Autophagy in Human Pancreatic Cancer Cells by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin
Autor: Phillip Tremblay, Kevinjeet Mahngar, Jonathan Collins, Pardis Akbari-Asl, Dennis Ma, Tomas Hudlicky, Siyaram Pandey
Publikováno v: American Journal of Biomedical Sciences. :278-291
Pancreatic cancer is amongst the deadliest cancers in the world. It is associated with poor prognosis, is notorious for developing chemoresistance, and very few approved chemotherapeutics are available to treat this disease. The natural compound panc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b03ac9fbe7315b7b095c9cc84c00c7d
https://doi.org/10.5099/aj110400278
Zobrazit plný text záznamu
4
Evaluation of the Efficacy & Biochemical Mechanism of Cell Death Induction by Piper longum Extract Selectively in In-Vitro and In-Vivo Models of Human Cancer Cells
Autor: Alessia Roma, John T. Arnason, Pamela Ovadje, Dennis Ma, Siyaram Pandey, Jose-Antonio Guerrero, Matthew Steckle, Phillip Tremblay
Publikováno v: PLoS ONE, Vol 9, Iss 11, p e113250 (2014)
PLoS ONE
Background Currently chemotherapy is limited mostly to genotoxic drugs that are associated with severe side effects due to non-selective targeting of normal tissue. Natural products play a significant role in the development of most chemotherapeutic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968463b660a0defbdaef2dd0501ef6e9
https://doi.org/10.1371/journal.pone.0113250
Zobrazit plný text záznamu
6
Selective Cytotoxicity against Human Osteosarcoma Cells by a Novel Synthetic C-1 Analogue of 7-Deoxypancratistatin Is Potentiated by Curcumin
Autor: Jonathan Collins, Phillip Tremblay, Siyaram Pandey, Tomas Hudlicky, Dennis Ma, Kevinjeet Mahngar
Publikováno v: PLoS ONE, Vol 6, Iss 12, p e28780 (2011)
PLoS ONE
The natural compound pancratistatin (PST) is a non-genotoxic inducer of apoptosis in a variety of cancers. It exhibits cancer selectivity as non-cancerous cells are markedly less sensitive to PST. Nonetheless, PST is not readily synthesized and is pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ee4d05c3af579a88bd84551b3ee6ba
https://doi.org/10.1371/journal.pone.0028780
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje