Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Phillip T. Leese"'
Autor:
Phillip T. Leese, Robert J. Noveck, Jolene S. Shorr, Catherine M. Woods, Kathryn E. Flaim, Peter E. Keipert
Publikováno v:
Anesthesia & Analgesia. 91:804-811
Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were p
Autor:
Catherine M. Woods, Edward J. Shannon, Peter E. Keipert, Jolene S. Shorr, Phillip T. Leese, K. E. Flaim, Robert Noveck
Publikováno v:
Anesthesia & Analgesia. 91:812-822
Particle size distribution is a major determinant of particle clearance by the mononuclear phagocytic system and the potential for concomitant activation of resident macrophages. To test the safety of a second-generation perflubron-based emulsion (60
Autor:
Neil F. Oldfield, Joseph W. Massarella, Janet Schmitt-Muskus, Indravadan H. Patel, Angela T. Melia, Theodore Crews, Stuart B. Teller, J. Zhi, Randall J Erb, Phillip T Leese
Publikováno v:
Clinical Pharmacology and Therapeutics. 56:530-536
To characterize the plasma concentration–effect relationship of flumazenil in the presence of a predefined midazolam level, a double-blind, placebo-controlled, randomized two-way crossover study was conducted in nine healthy male subjects. After re
Autor:
Robert Abels, Phillip T. Leese, Howard S. Weintraub, Barbara Marinan, Shiew-Mei Huang, Thomas B. Marriott
Publikováno v:
Biopharmaceutics & Drug Disposition. 8:561-569
Etintidine HCl is a potent H2-blocker. The effect of clinical doses of etintidine on the disposition of theophylline was investigated in 10 male volunteers. This was a double-blind, two-way crossover study. Each subject received etintidine (400 mg) o