Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Phillip Sung"'
Autor:
Emilia A H Vanni, Joseph W Foley, Andrew J Davison, Marvin Sommer, Dongmei Liu, Phillip Sung, Jennifer Moffat, Leigh Zerboni, Ann M Arvin
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009166 (2020)
Herpes simplex virus 1 (HSV-1) infects skin and mucosal epithelial cells and then travels along axons to establish latency in the neurones of sensory ganglia. Although viral gene expression is restricted during latency, the latency-associated transcr
Externí odkaz:
https://doaj.org/article/4837bd804ca54bc4b614cfe9b39aa1fc
Autor:
Nandini Sen, Gourab Mukherjee, Adrish Sen, Sean C. Bendall, Phillip Sung, Garry P. Nolan, Ann M. Arvin
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 633-645 (2014)
Although pathogens must infect differentiated host cells that exhibit substantial diversity, documenting the consequences of infection against this heterogeneity is challenging. Single-cell mass cytometry permits deep profiling based on combinatorial
Externí odkaz:
https://doaj.org/article/b1f5f45ef0eb4859adbccdc38da69a07
Autor:
Phillip Sung, Ann M. Arvin, Leigh Zerboni, Dongmei Liu, Andrew J. Davison, Emilia A. H. Vanni, Jennifer F. Moffat, Marvin Sommer, Joseph W. Foley
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009166 (2020)
PLoS Pathogens
PLoS Pathogens
Herpes simplex virus 1 (HSV-1) infects skin and mucosal epithelial cells and then travels along axons to establish latency in the neurones of sensory ganglia. Although viral gene expression is restricted during latency, the latency-associated transcr
Publikováno v:
Virology. 523:110-120
Knowledge about the function of varicella-zoster virus glycoprotein M is limited; the requirement of gM for skin and neural tropism are unknown. VZV gM contains two predicted YXXΦ trafficking motifs and a dileucine motif in the carboxyl-terminus. We
Publikováno v:
Journal of Virology. 92
Both type I and type II interferons (IFNs) have been implicated in the host defense against varicella-zoster virus (VZV), a common human herpesvirus that causes varicella and zoster. The purpose of this study was to compare their contributions to the
Varicella-zoster virus (VZV) is the skin-tropic human alphaherpesvirus responsible for both varicella-zoster and herpes zoster. Varicella-zoster and herpes zoster skin lesions have similar morphologies, but herpes zoster occurs disproportionally in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46cab0a3f1083b28a52f90701be29be
https://europepmc.org/articles/PMC5952162/
https://europepmc.org/articles/PMC5952162/
Publikováno v:
Virology. 492
VZV IE62 is an essential, immediate-early, tegument protein and consists of five domains. We generated recombinant viruses carrying mutations in the first three IE62 domains and tested their influence on VZV replication kinetics. The mutations in dom
Autor:
Phillip Sung, Xibing Che, Nandini Sen, Leigh Zerboni, Ann M. Arvin, Jaya Rajamani, Jason Ptacek
Publikováno v:
Proceedings of the National Academy of Sciences. 109:600-605
Varicella-zoster virus (VZV) is a human α-herpesvirus that causes varicella (chickenpox) during primary infection and zoster (shingles) upon reactivation. Like other viruses, VZV must subvert the intrinsic antiviral defenses of differentiated human
Autor:
Linda L. Yasukawa, Barbara Sullivan, Ann M. Arvin, Mimi Fang, Phillip Sung, Mary Rinki, Rima Hanna-Wakim, Ross DeHovitz, Hayley A. Gans
Publikováno v:
The Journal of Infectious Diseases. 200:1921-1927
Background The susceptibility of infants to infections is well defined clinically, and immunologic abnormalities have been described. Immune maturation is complex, however, and the interval during which changes occur during childhood has not been ide
Publikováno v:
The Journal of Infectious Diseases. 197:1669-1675
Wild-type mumps virus continues to cause outbreaks throughout the world despite widespread immunization programs. An outbreak in the United States in 2006 resulted in 5783 confirmed or probable mumps cases [1]. In this outbreak, high rates of mumps c