Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Phillip Stafford"'
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Space exploration’s advancement toward long-duration missions prompts intensified research on physiological effects. Despite adaptive physiological stability in some variables, persistent changes affect genome integrity, immune response, a
Externí odkaz:
https://doaj.org/article/f3afa2749fc64ecc94814d2ead9dada9
Autor:
Rupesh Kanchi Ravi, Phillip Stafford, Hanlin (Harry) Gao, Jakub Sram, John Gao, Mickey Li, Erica Trinh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/f7f99ae415584e578707fa4fdc558609
Autor:
Robayet Chowdhury, Alexander T Taguchi, Laimonas Kelbauskas, Phillip Stafford, Chris Diehnelt, Zhan-Gong Zhao, Phillip C Williamson, Valerie Green, Neal W Woodbury
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 6, p e1010773 (2023)
Past studies have shown that incubation of human serum samples on high density peptide arrays followed by measurement of total antibody bound to each peptide sequence allows detection and discrimination of humoral immune responses to a variety of inf
Externí odkaz:
https://doaj.org/article/8ae2241bc603481c92953c92f17717cd
Publikováno v:
Current Oncology, Vol 28, Iss 6, Pp 4485-4503 (2021)
Nuclear protein of testis (NUT), a protein product of the NUTM1 gene (located on the long arm of chromosome 15) with highly restricted physiologic expression in post-meiotic spermatids, is the oncogenic driver of a group of emerging neoplasms when fu
Externí odkaz:
https://doaj.org/article/05b8d2bb57d140afaf59c58f3b21edd2
Autor:
Andrew Elliott, Michelle Saul, Jia Zeng, John L. Marshall, Edward S. Kim, Misako Nagasaka, Heinz-Josef Lenz, Lee Schwartzberg, David Spetzler, Jim Abraham, Joanne Xiu, Phillip Stafford, W. Michael Korn
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Patients with cancer demonstrate particularly poor outcomes from COVID-19. To provide information essential for understanding the biologic underpinnings of this association, we analyzed whole-transcriptome RNA expression data obtained from a
Externí odkaz:
https://doaj.org/article/de659d81a8a243fe8527f66b921f70ed
Autor:
Michelle Saul, Kelsey Poorman, Hongseok Tae, Ari Vanderwalde, Phillip Stafford, David Spetzler, Wolfgang M. Korn, Zoran Gatalica, Jeff Swensen
Publikováno v:
Cancer Medicine, Vol 9, Iss 17, Pp 6452-6460 (2020)
Abstract Microsatellite instability (MSI) is a key secondary effect of a defective DNA mismatch repair mechanism resulting in incorrectly replicated microsatellites in many malignant tumors. Historically, MSI detection has been performed by fragment
Externí odkaz:
https://doaj.org/article/2f60b561ae7c4d9e89100e6c899c2446
Autor:
Zoran Gatalica, Semir Vranic, Božo Krušlin, Kelsey Poorman, Phillip Stafford, Denisa Kacerovska, Wijendra Senarathne, Elena Florento, Elma Contreras, Alexandra Leary, April Choi, Gino K. In
Publikováno v:
Cancer Medicine, Vol 9, Iss 4, Pp 1441-1450 (2020)
Abstract Background Primary Extra‐mammary Paget's disease (EMPD) is a very rare cutaneous adenocarcinoma affecting anogenital or axillary regions. It is characterized by a prolonged course with recurrences and eventually distant metastatic spread f
Externí odkaz:
https://doaj.org/article/f88b08f4d8324c49a38f425e780ce858
Autor:
Stacey M. Gargano, Wijendra Senarathne, Rebecca Feldman, Elena Florento, Phillip Stafford, Jeffrey Swensen, Semir Vranic, Zoran Gatalica
Publikováno v:
Cancer Medicine, Vol 8, Iss 17, Pp 7322-7329 (2019)
Abstract Salivary duct carcinoma (SDC) is a rare, aggressive salivary gland malignancy, which often presents at an advanced stage. A proportion of SDC are characterized by HER2 amplification and/or overexpression of androgen receptor (AR), which coul
Externí odkaz:
https://doaj.org/article/cd244866bbe04fd3b2e4d115fa319925
Autor:
Jim Abraham, Amy B. Heimberger, John Marshall, Elisabeth Heath, Joseph Drabick, Anthony Helmstetter, Joanne Xiu, Daniel Magee, Phillip Stafford, Chadi Nabhan, Sourabh Antani, Curtis Johnston, Matthew Oberley, Wolfgang Michael Korn, David Spetzler
Publikováno v:
Translational Oncology, Vol 14, Iss 3, Pp 101016- (2021)
Cancer of Unknown Primary (CUP) occurs in 3–5% of patients when standard histological diagnostic tests are unable to determine the origin of metastatic cancer. Typically, a CUP diagnosis is treated empirically and has very poor outcomes, with media
Externí odkaz:
https://doaj.org/article/469bb8ab092d4f4b969ca0049de6630e
Autor:
Phillip Stafford, Stephen Albert Johnston, Orhun H Kantarci, Ameneh Zare-Shahabadi, Arthur Warrington, Moses Rodriguez
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229080 (2020)
Therapeutic monoclonal antibodies have the potential to work as biological therapeutics. OKT3, Herceptin, Keytruda and others have positively impacted healthcare. Antibodies evolved naturally to provide high specificity and high affinity once mature.
Externí odkaz:
https://doaj.org/article/bfbc224862bf4fd68945028b4bd55d8c