Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Phillip S. Oates"'
Autor:
Umbreen Ahmed, Phillip S. Oates
Publikováno v:
Nutrition Research. 33:126-135
Because dietary fats affect the regulation and use of body iron, we hypothesized that iron regulatory and transport genes may be affected by dietary fat. A model of early-stage I to II, nonalcoholic fatty liver was used in which rats were fed standar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e6f2d6af7baefd3a28702510bfed53
https://doi.org/10.1016/j.nutres.2012.11.012
https://doi.org/10.1016/j.nutres.2012.11.012
Autor:
Phillip S. Oates, Umbreen Ahmed
Publikováno v:
Journal of Gastroenterology and Hepatology. 22:1378-1387
Iron is a micronutrient that is an essential component that drives many metabolic reactions. Too little iron leads to anemia and too much iron increases the oxidative stress of body tissues leading to inflammation, cell death, and system organ dysfun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d6854e9f1346ae372bc9717bacae98
https://doi.org/10.1111/j.1440-1746.2007.04950.x
https://doi.org/10.1111/j.1440-1746.2007.04950.x
Autor:
Phillip S. Oates
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 455:201-213
Rigorous regulation of iron absorption is required to meet the requirements of the body and to limit excess iron accumulation that can produce oxidative stress. Regulation of iron absorption is controlled by hepcidin and probably by the crypt program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207c17f82d7d7888192fde5e723ebc98
https://doi.org/10.1007/s00424-007-0264-9
https://doi.org/10.1007/s00424-007-0264-9
Autor:
Adrian R. West, Phillip S. Oates
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 289:G1108-G1114
Disaccharidases are important digestive enzymes whose activities can be reduced by iron deficiency. We hypothesise that this is due to reduced gene expression, either by impairment to enterocyte differentiation or by iron-sensitive mechanisms that re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c97fa42b9bb3bbc4d932c49df1d14d6
https://doi.org/10.1152/ajpgi.00195.2005
https://doi.org/10.1152/ajpgi.00195.2005
Autor:
Phillip S. Oates, Carla Thomas
Publikováno v:
Gut. 53:44-49
Absorption of non-haeme iron occurs mainly in the duodenum. It involves the divalent metal transporter 1 (DMT1) in the uptake of ferrous Fe(II) iron and the basolateral transporter ferroportin/IREG-1/MTP-1/SLC40A1 in its release. Whether ferroportin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83caa803ffe0736c05e08d6f4268ca3
https://doi.org/10.1136/gut.53.1.44
https://doi.org/10.1136/gut.53.1.44
Publikováno v:
Hepatology. 38:967-977
The effects of cellular proliferation on the uptake of transferrin-bound iron (Tf-Fe) and expression of transferrin receptor-1 (TfR1) and transferrin receptor-2 (TfR2) were investigated using a human hepatoma (HuH7) cell line stably transfected with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140386325eb74e3da75fd3ba1be82c09
https://doi.org/10.1002/hep.1840380423
https://doi.org/10.1002/hep.1840380423
Autor:
Phillip S. Oates, Evan H. Morgan
Publikováno v:
Blood Cells, Molecules, and Diseases. 29:384-399
Iron absorption from the small intestine is regulated according to the body's needs, increasing in iron deficiency and decreasing in iron overload. It has been proposed that the efficiency of absorption is determined by the amount of iron acquired by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04217b3c3dc9d3c81c84543e7a3a56c
https://doi.org/10.1006/bcmd.2002.0578
https://doi.org/10.1006/bcmd.2002.0578
Autor:
Carla Thomas, Phillip S. Oates
Publikováno v:
The Journal of Nutrition. 132:680-687
Regulation of iron absorption, which is the primary mechanism for maintaining body iron stores, occurs primarily in the proximal small intestine. Recent identification of proteins that are involved in iron absorption such as the uptake transporter-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5468f093e2861e0bb7f0ca1e6dc3d66f
https://doi.org/10.1093/jn/132.4.680
https://doi.org/10.1093/jn/132.4.680
Publikováno v:
GSTF Journal of Advances in Medical Research. 1
The liver is the major site for lipoprotein processing and iron storage. Non-alcoholic fatty liver disease (NAFLD) is a broad spectrum of chronic liver disorder with progressive factors hypothesized to include impaired hepatic lipid metabolism and ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90fd7b34fe3cb435b1a438594e2835d9
https://doi.org/10.5176/2345-7201_1.2.18
https://doi.org/10.5176/2345-7201_1.2.18
Publikováno v:
1st Annual International Conference on Advanced Research: Physiology (ARP 2014).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4025b32d8fc6a4926efbe18f931a3f70
https://doi.org/10.5176/2382-607x_arp14.17
https://doi.org/10.5176/2382-607x_arp14.17