Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Phillip R Heaton"'
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30165 (2012)
Sumoylation is a highly dynamic process that plays a role in a multitude of processes ranging from cell cycle progression to mRNA processing and cancer. A previous study from our lab demonstrated that SUMO plays an important role in keratinocyte diff
Externí odkaz:
https://doaj.org/article/1649d13eb40449cfac2a0750414b9773
Autor:
Kenneth Gavina, Lauren C. Franco, Christopher M. Robinson, Weston Hymas, Guang-Sheng Lei, Will Sinclair, Tara Hall, John Carlquist, John-Paul Lavik, Christopher L. Emery, Phillip R. Heaton, David Hillyard, Bert K. Lopransi, Ryan F. Relich
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The demand for testing during the coronavirus disease 2019 (COVID-19) pandemic has resulted in the production of several different commercial platforms and laboratory-developed assays for the detection of severe acute respiratory syndrome co
Externí odkaz:
https://doaj.org/article/caf803cdbd0d4ab49b0813ed502e2a99
Publikováno v:
Molecular Immunology. 49:260-272
Two members, Bright/ARID3A and Bdp/ARID3B, of the ARID (AT-Rich Interaction Domain) transcription family are distinguished by their ability to specifically bind to DNA and to self-associate via a second domain, REKLES. Bright and Bdp positively regul
Autor:
Nancy Raab-Traub, Blossom Damania, Sezgin Özgür, Rachel Hood Edwards, David G. Meckes, Harsha P. Gunawardena, Robert M. DeKroon, Phillip R. Heaton, Jack D. Griffith
The human gamma herpesviruses, Kaposi sarcoma-associated virus (KSHV) and EBV, are associated with multiple cancers. Recent evidence suggests that EBV and possibly other viruses can manipulate the tumor microenvironment through the secretion of speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540da680c4a2ea3962c7a808c1b3e373
https://europepmc.org/articles/PMC3732930/
https://europepmc.org/articles/PMC3732930/
Publikováno v:
Virus research. 158(1-2)
The human papillomavirus oncogenic protein, E6, interacts with a number of cellular proteins, and for some targets, E6 directs their degradation through the ubiquitin-proteasome pathway. Post-translational modification with ubiquitin-like modifiers,
Autor:
Phillip R. Heaton, Van G. Wilson
Publikováno v:
Expert review of proteomics. 5(1)
The Small Ubiquitin-like Modifier proteins (Smt3 in yeast and SUMOs 1-4 in vertebrates) are members of the ubiquitin super family. Like ubiquitin, the SUMOs are protein modifiers that are covalently attached to the epsilon amino group of lysine resid
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 1, p e30165 (2012)
PLoS ONE, Vol 7, Iss 1, p e30165 (2012)
Sumoylation is a highly dynamic process that plays a role in a multitude of processes ranging from cell cycle progression to mRNA processing and cancer. A previous study from our lab demonstrated that SUMO plays an important role in keratinocyte diff
Publikováno v:
Virology. (1):176-183
The stability of papillomavirus E2 proteins is regulated by proteasomal degradation, and regulation of degradation could contribute to the higher expression levels of E2 proteins observed in suprabasal layers of differentiated skin. We have recently