Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Phillip Prisayanh"'
From Insect Bites to a Skin Autoimmune Disease: A Conceivable Pathway to Endemic Pemphigus Foliaceus
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In the endemic variants of pemphigus foliaceus (PF), in Brazil and Tunisia, patients generate pathogenic IgG4 anti-desmoglein 1 autoantibodies. Additionally, these patients possess antibodies against salivary proteins from sand flies that react with
Externí odkaz:
https://doaj.org/article/09490b5a53a54d68bbbe1c86832ade13
Autor:
Valeria Aoki, Maha Abdeladhim, Ning Li, Pedro Cecilio, Phillip Prisayanh, Luis A. Diaz, Jesus G. Valenzuela
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Sand flies are hematophagous insects responsible for the transmission of vector-borne diseases to humans. Prominent among these diseases is Leishmaniasis that affects the skin and mucous surfaces and organs such as liver and spleen. Importantly, the
Externí odkaz:
https://doaj.org/article/9becf8a23d1d4ddb82c8c0756f8b9ab5
Autor:
Valeria Aoki, Maha Abdeladhim, Ning Li, Pedro Cecilio, Phillip Prisayanh, Luis A. Diaz, Jesus G. Valenzuela
Publikováno v:
Frontiers in cellular and infection microbiology. 12
Sand flies are hematophagous insects responsible for the transmission of vector-borne diseases to humans. Prominent among these diseases is Leishmaniasis that affects the skin and mucous surfaces and organs such as liver and spleen. Importantly, the
Autor:
Valeria Aoki, Horacio Friedman, Brenda Temple, Luis A. Diaz, Bahjat F. Qaqish, Jesus G. Valenzuela, Gunter Hans-Filho, Phillip Prisayanh, Morgan Karetnick, Samantha M Herbert, Evandro A. Rivitti
Publikováno v:
Journal of Investigative Dermatology. 140:2332-2342.e10
Fogo selvagem (FS) is a blistering skin disease caused by pathogenic IgG4 autoantibodies to desmoglein 1 (DSG1). Preclinical FS and leishmaniasis are endemic to certain regions of Brazil and exhibit nonpathogenic anti-DSG1 antibodies. Recurring bites
Autor:
Ye Qian, O.J. Harrison, Lawrence Shapiro, Phillip Prisayanh, A. Roth, Ning Li, Barry Honig, Luis A. Diaz, Julia Brasch, Zhi Liu, Flor Evangelista, Brenda Temple, Donna A. Culton
Publikováno v:
Journal of autoimmunity. 89
Fogo Selvagem (FS), the endemic form of pemphigus foliaceus, is mediated by pathogenic IgG4 autoantibodies against the amino-terminal extracellular cadherin domain of the desmosomal cadherin desmoglein 1 (Dsg1). Here we define the detailed epitopes o
Autor:
Evandro A. Rivitti, Morgan Karetnick, B. Qaquish, Brenda Temple, Valeria Aoki, Horacio Friedman, Jesus G. Valenzuela, Samantha M Herbert, Luis A. Diaz, Gunter Hans-Filho, Phillip Prisayanh
Publikováno v:
Journal of Investigative Dermatology. 139:S7
Publikováno v:
Br J Dermatol
Summary Background Pemphigus vulgaris (PV) is an autoimmune skin blistering disease. The main targets of autoantibodies are the desmosomal proteins desmoglein (Dsg)3 and Dsg1. Anti-E-cadherin antibody is the second most frequent antibody found in pem
Autor:
Mike Maldonado, Evandro A. Rivitti, Donna A. Culton, Valeria Aoki, Phillip Prisayanh, Gunter Hans-Filho, Gustavo Flores, Bahjat F. Qaqish, Kirk A. James, Luis A. Diaz
Publikováno v:
The Journal of investigative dermatology
It is well established that autoantibodies against desmoglein 3 and desmoglein 1 (Dsg1) are relevant in the pathogenesis of pemphigus vulgaris and pemphigus foliaceus, including its endemic form fogo selvagem (FS). Isolated reports have shown that in
Autor:
A. Roth, Donna A. Culton, Ye Qian, Phillip Prisayanh, Barry Honig, Brenda Temple, O.J. Harrison, Ning Li, Luis A. Diaz, Zhi Liu, Lawrence Shapiro, Flor Evangelista, Julia Brasch
Publikováno v:
Journal of Investigative Dermatology. 138:S7
Autor:
Phillip Prisayanh, Minglang Zhao, Ning Li, Luis A. Diaz, Zhi Liu, Derry C. Roopenian, Simon Warren, Julio Hilario-Vargas
Publikováno v:
Journal of Clinical Investigation. 115:3440-3450
Numerous mechanisms of action have been proposed for intravenous Ig (IVIG). In this study, we used IgG passive transfer murine models of bullous pemphigoid (BP), pemphigus foliaceus (PF), and pemphigus vulgaris (PV) to test the hypothesis that the ef