Cytogenetically cryptic PML::RARA fusion in acute promyelocytic leukemia: Testing strategies in the modern era

Autor: Kirill Karlin, Christine Bryke, Ajoy Dias, Phillip Michaels

Publikováno v: Leukemia Research Reports, Vol 17, Iss , Pp 100320- (2022)

Acute promyelocytic leukemia (APL) is a unique leukemia that is characterized by the PML::RARA fusion. This fusion is often detected by conventional karyotype and fluorescence in situ hybridization (FISH); however, rare cases are cryptic and require

Externí odkaz: https://doaj.org/article/f9b252612b9c42f7ae3306720b1cc884

The 5th edition of the World Health Organization classification of haematolymphoid tumours: myeloid and histiocytic/dendritic neoplasms

Autor: Joseph D. Khoury, Eric Solary, Oussama Abla, Yassmine Akkari, Rita Alaggio, Jane F. Apperley, Rafael Bejar, Emilio Berti, Lambert Busque, John K. C. Chan, Weina Chen, Xueyan Chen, Wee-Joo Chng, John K. Choi, Isabel Colmenero, Sarah E. Coupland, Nicholas C. P. Cross, Daphne De Jong, M. Tarek Elghetany, Emiko Takahashi, Jean-Francois Emile, Judith Ferry, Linda Fogelstrand, Michaela Fontenay, Ulrich Germing, Sumeet Gujral, Torsten Haferlach, Claire Harrison, Jennelle C. Hodge, Shimin Hu, Joop H. Jansen, Rashmi Kanagal-Shamanna, Hagop M. Kantarjian, Christian P. Kratz, Xiao-Qiu Li, Megan S. Lim, Keith Loeb, Sanam Loghavi, Andrea Marcogliese, Soheil Meshinchi, Phillip Michaels, Kikkeri N. Naresh, Yasodha Natkunam, Reza Nejati, German Ott, Eric Padron, Keyur P. Patel, Nikhil Patkar, Jennifer Picarsic, Uwe Platzbecker, Irene Roberts, Anna Schuh, William Sewell, Reiner Siebert, Prashant Tembhare, Jeffrey Tyner, Srdan Verstovsek, Wei Wang, Brent Wood, Wenbin Xiao, Cecilia Yeung, Andreas Hochhaus

Publikováno v: Leukemia, 36, 7, pp. 1703-1719
Leukemia
Leukemia, 2022, 36 (7), pp.1703-1719. ⟨10.1038/s41375-022-01613-1⟩
Leukemia, 36, 1703-1719
Khoury, J D, Solary, E, Abla, O, Akkari, Y, Alaggio, R, Apperley, J F, Bejar, R, Berti, E, Busque, L, Chan, J K C, Chen, W, Chen, X, Chng, W-J, Choi, J K, Colmenero, I, Coupland, S E, Cross, N C P, de Jong, D, Elghetany, M T, Takahashi, E, Emile, J-F, Ferry, J, Fogelstrand, L, Fontenay, M, Germing, U, Gujral, S, Haferlach, T, Harrison, C, Hodge, J C, Hu, S, Jansen, J H, Kanagal-Shamanna, R, Kantarjian, H M, Kratz, C P, Li, X-Q, Lim, M S, Loeb, K, Loghavi, S, Marcogliese, A, Meshinchi, S, Michaels, P, Naresh, K N, Natkunam, Y, Nejati, R, Ott, G, Padron, E, Patel, K P, Patkar, N, Picarsic, J, Platzbecker, U, Roberts, I, Schuh, A, Sewell, W, Siebert, R, Tembhare, P, Tyner, J, Verstovsek, S, Wang, W, Wood, B, Xiao, W, Yeung, C & Hochhaus, A 2022, ' The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours : Myeloid and Histiocytic/Dendritic Neoplasms ', Leukemia, vol. 36, no. 7, pp. 1703-1719 . https://doi.org/10.1038/s41375-022-01613-1

The upcoming 5th edition of the World Health Organization (WHO) Classification of Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers arising in various organ systems within a single relational database. This paper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e505729c9f9bde8ff82d51d719fed2e
http://hdl.handle.net/10044/1/103319

Emerging patterns in clonal haematopoiesis

Autor: Daniel Xia, Sagi Abelson, Jose-Mario Capo-Chichi, Robert P. Hasserjian, Rosemarie Tremblay-Le May, Phillip Michaels

Publikováno v: Journal of Clinical Pathology. 72:453-459

Clonal haematopoiesis (CH) is defined by the presence of acquired mutations and/or cytogenetic abnormalities in haematopoietic cells. By definition, these premalignant clones do not meet criteria for haematopoietic neoplasms listed in the Revised Fou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd222f61295b5c4900d63521cca8455
https://doi.org/10.1136/jclinpath-2019-205851

Mutational analysis of hematologic neoplasms in 164 paired peripheral blood and bone marrow samples by next-generation sequencing

Autor: Phillip Michaels, Dahai Wang, Annette S. Kim, Fabienne Lucas

Publikováno v: Blood Adv

The classification, risk stratification, and treatment selection of patients with hematologic malignancies are heavily influenced by recurrent molecular alterations determined by next-generation sequencing (NGS).1-5 Peripheral blood (PB) and bone mar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1cc1340aa53de2ba58a28ff08a7838
https://europepmc.org/articles/PMC7509881/

Current assessment of the Red Rectangle band problem

Autor: Christopher M. Anderson, Timothy W. Schmidt, Rob Sharp, Phillip Michaels, Lawrence S. Bernstein, H. Van Winckel, Robert J. Glinski, Michael L. Sitko

Publikováno v: Astrophysics and Space Science. 323:337-344

In this paper we discuss our insights into several key problems in the identification of the Red Rectangle Bands (RRBs). We have combined three independent sets of observations in order to try to define the constraints guiding the bands. We provide a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582cbc2c0eb7ec7e2003111de3585867
https://doi.org/10.1007/s10509-009-0084-9