Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Phillip Mackie"'
Autor:
Adithya Gopinath, Phillip Mackie, Basil Hashimi, Anna Marie Buchanan, Aidan R. Smith, Rachel Bouchard, Gerry Shaw, Martin Badov, Leila Saadatpour, Aryn Gittis, Adolfo Ramirez-Zamora, Michael S. Okun, Wolfgang J. Streit, Parastoo Hashemi, Habibeh Khoshbouei
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-14 (2022)
Abstract Parkinson’s disease (PD) is marked by a loss of dopamine neurons, decreased dopamine transporter (DAT) and tyrosine hydroxylase (TH) expression. However, this validation approach cannot be used for diagnostic, drug effectiveness or investi
Externí odkaz:
https://doaj.org/article/1e1f115b1bba4304b630a841b7066a0a
Autor:
Adithya Gopinath, Martin Badov, Madison Francis, Gerry Shaw, Anthony Collins, Douglas R. Miller, Carissa A. Hansen, Phillip Mackie, Malú Gámez Tansey, Abeer Dagra, Irina Madorsky, Adolfo Ramirez-Zamora, Michael S. Okun, Wolfgang J. Streit, Habibeh Khoshbouei
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract Most, if not all, peripheral immune cells in humans and animals express tyrosine hydroxylase (TH), the rate limiting enzyme in catecholamine synthesis. Since TH is typically studied in the context of brain catecholamine signaling, little is
Externí odkaz:
https://doaj.org/article/806b43b093964f069d4b1c251c749341
Autor:
Adithya Gopinath, Martin Badov, Madison Francis, Gerry Shaw, Anthony Collins, Douglas R. Miller, Carissa A. Hansen, Phillip Mackie, Malú Gámez Tansey, Abeer Dagra, Irina Madorsky, Adolfo Ramirez-Zamora, Michael S. Okun, Wolfgang J. Streit, Habibeh Khoshbouei
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/ca8cab54aa3e4ba5888463af72c9fddd
Autor:
A. Nielsen, K. Runner, Adolfo Ramirez-Zamora, Stephanie M. Matt, Long Yan, Peter J. Gaskill, Wolfgang J. Streit, Phillip Mackie, K. Adachi, R.A. Nolan, Adithya Gopinath, Habibeh Khoshbouei, J. McNamee, J. Ricklan, Andria L. Doty, Michael S. Okun, D. M. Montas
Monocyte-derived macrophages are key players in tissue homeostasis and disease regulated by a variety of signaling molecules. Recent literature has highlighted the ability for biogenic amines to regulate macrophage functions, but the mechanisms gover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33638636463c8cf3c213dd941c9a4907
https://doi.org/10.1101/2021.09.08.459459
https://doi.org/10.1101/2021.09.08.459459
Autor:
Phillip Mackie, Christopher J. Martyniuk, Douglas R. Miller, Habibeh Khoshbouei, Fatima Shaerzadeh, Min Lin, Joyonna Gamble-George
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-25 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Pathophysiological changes in dopamine neurons precede their demise and contribute to the early phases of Parkinson’s disease (PD). Intracellular pathological inclusions of the protein α-synuclein within dopaminergic neurons are a cardinal feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8664c964a84e68c962a5db8f8f2948ad
https://doi.org/10.1186/s40478-021-01203-9
https://doi.org/10.1186/s40478-021-01203-9
Autor:
Peter J. Gaskill, K. Runner, E. A. Nickoloff-Bybel, Phillip Mackie, Stephanie M. Matt, Habibeh Khoshbouei
Publikováno v:
Brain Behav Immun
Dopaminergic dysfunction has long been connected to the development of HIV infection in the CNS. Our previous data showed that dopamine increases HIV infection in human macrophages by increasing the susceptibility of primary human macrophages to HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bdec0f32f107f9d549d3f873c54d5f
https://doi.org/10.1016/j.bbi.2019.08.191
https://doi.org/10.1016/j.bbi.2019.08.191
Autor:
Martin Badov, Adithya Gopinath, Habibeh Khoshbouei, Joshua Riklan, Adolfo Ramirez-Zamora, K. Runner, Michael S. Okun, John McNamee, Rachel Nolan, Basil Hashimi, Phillip Mackie, Andria L. Doty, Alyssa Nielsen, Peter J. Gaskill, Dominic Montas, Wolfgang J. Streit
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55fd6d6a33b3e331d053ef102f1abd24
https://doi.org/10.1096/fasebj.2021.35.s1.03180
https://doi.org/10.1096/fasebj.2021.35.s1.03180
Autor:
Habibeh Khoshbouei, Abeer Dagra, Douglas R. Miller, Madison Francis, Martin Badov, Anthony Collins, Wolfgang J. Streit, Phillip Mackie, Michael S. Okun, Carissa A. Hansen, Irina Madorsky, Adithya Gopinath, Malú G. Tansey, Gerry Shaw, Adolfo Ramirez-Zamora
Publikováno v:
NPJ Parkinson's Disease
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-15 (2021)
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-15 (2021)
Most, if not all, peripheral immune cells in humans and animals express tyrosine hydroxylase (TH), the rate limiting enzyme in catecholamine synthesis. Since TH is typically studied in the context of brain catecholamine signaling, little is known abo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e6b9fcee5c099c3839273e3670c5af
https://doi.org/10.1101/2021.04.13.439627
https://doi.org/10.1101/2021.04.13.439627
Autor:
Emily Nickoloff, Phillip Mackie, Peter J. Gaskill, Leila Saadatpour, Habibeh Khoshbouei, Joe J Lebowitz
Publikováno v:
Brain, Behavior, and Immunity. 70:21-35
The second-most common neurodegenerative disease, Parkinson’s Disease (PD) has three hallmarks: dysfunctional dopamine transmission due, at least in part, to dopamine neuron degeneration; intracellular inclusions of α-synuclein aggregates; and neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764178dc83b3943ce1c9c4551b886423
https://doi.org/10.1016/j.bbi.2018.03.020
https://doi.org/10.1016/j.bbi.2018.03.020
Publikováno v:
Cardiology in the Young. 31:831-832
Chest radiography compares left ventricular decompression in the same patient supported with extracorporeal membrane oxygenation with atrial septal fenestration and subsequently supported with left ventricular assist device with apical cannulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4ae524600dea0e72a70396860d2efe
https://doi.org/10.1017/s1047951121001906
https://doi.org/10.1017/s1047951121001906