Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Phillip M. Hutchins"'
Publikováno v:
Cardiovascular Research. 32:772-780
Objective: The purpose of this manuscript is to review the literature concerning the alterations in the microvasculature in experimental hypertension and aging. We also present new unpublished data and results where previous studies have not addresse
Publikováno v:
Microvascular Research. 39:129-139
Intrinsic rhythmic changes in the diameter of pial cerebral arterioles (30-70 microns) in anesthetized normotensive and hypertensive rats were assessed in vivo to determine if any significant differences exist between the two strains. All diameter me
Publikováno v:
Endocrinology. 138(8)
Several reports have demonstrated that cerebral blood flow decreases with age and may contribute to neurodegenerative changes found in aging animals and man. Because GH and insulin-like growth factor 1 (IGF-1) decrease with age and have an important
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 202(3)
This study was undertaken to explore the time course of the metabolic response to isohemic blood volume expansion (30%) in normotensive, unanesthetized Sprague-Dawley rats. Whole blood, drawn from a femoral artery catheter of conscious donor rats, wa
Publikováno v:
The Resistance Vasculature ISBN: 9781461267461
This chapter will present the advantages and disadvantages of chronic in vivo preparations and describe the state of the art for some of these preparations. Investigations employing chronic in vivo techniques offer many advantages. For example, tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad48c135f95c0d3149cef4bf357a84a4
https://doi.org/10.1007/978-1-4612-0403-9_5
https://doi.org/10.1007/978-1-4612-0403-9_5
Autor:
Thomas L. Smith, Colleen D. Lynch, Donald S. Prough, Jerry W. Dusseau, Phillip M. Hutchins, J. M. Fulton, Xiao-Quan Yuan, D. S. De Witt
Publikováno v:
The American journal of physiology. 258(5 Pt 2)
The chronic cranial window preparation allows repeated measurements of the same pial vessels in unanesthetized rats for several weeks and correlation with 24-h monitoring of hemodynamic variables. Nimodipine (20 mg) or placebo was given via two subcu
Publikováno v:
Microvascular Research. 13:125-130
The principal cardiovascular manifestations of essential hypertension are known to be an increase in peripheral vascular resistance and in systemic arterial blood pressure. However, it is not known if the increased vascular resistance is of appropria
Publikováno v:
Microvascular Research. 29:360-370
A lightweight, thermoneutral chamber design is introduced which permits the investigator to study, in vivo, intact skeletal muscle vasculature in the rat. The chamber, combined with established instrumentation (electromagnetic flowmetry and chronic c
Publikováno v:
Regulatory Peptides. 23:271-278
The effect of the intracerebroventricular (i.c.v.) injection of hypertonic sodium chloride on plasma atrial natriuretic peptide (ANP) and oxytocin (OT) was evaluated in conscious freely moving rats. A hypertonic or isotonic NaCl solution was injected
Autor:
Phillip M. Hutchins, Earl F. Ellis
Publikováno v:
Microvascular Research. 13:19-27
Earlier studies have shown that autonomic nerve system integrity is necessary for the spontaneously hypertensive rat (SHR) to demonstrate increased vasodepressor responses to depressor prostaglandins (PG). We compared normotensive rat (NR) and SHR mi