Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Phillip M Rappold"'
Autor:
Soyeon Lim, Adrianne S Chesser, Jonathan C Grima, Phillip M Rappold, David Blum, Serge Przedborski, Kim Tieu
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24620 (2011)
Abnormalities in mitochondrial function and epigenetic regulation are thought to be instrumental in Huntington's disease (HD), a fatal genetic disorder caused by an expanded polyglutamine track in the protein huntingtin. Given the lack of effective t
Externí odkaz:
https://doaj.org/article/8488f6096848471e9ca9f2beab9c1e23
Autor:
Rickinder Grewal, Hae Yoon G. Choung, Lisa L. Roberts, Timothy Beane, Luojing Chen, Daniel X. Gilroy, Phillip M. Rappold, Thu H. Le
Publikováno v:
Acta Oncologica. 61:1507-1511
Transmembrane protein 27 (TMEM27/collectrin), a glycoprotein and homolog of angiotensin-converting enzyme 2 (ACE2), is a regulator of renal amino acid uptake in the proximal tubule and may have a protective role in hypertension. Two previous reports
Autor:
Phillip M. Rappold, Lynda Vuong, Josef Leibold, Nicholas H. Chakiryan, Michael Curry, Fengshen Kuo, Erich Sabio, Hui Jiang, Briana G. Nixon, Ming Liu, Anders E. Berglund, Andrew W. Silagy, Eduardo A. Mascareno, Mahdi Golkaram, Mahtab Marker, Albert Reising, Alexander Savchenko, John Millholland, Ying-Bei Chen, Paul Russo, Jonathan Coleman, Ed Reznik, Brandon J. Manley, Irina Ostrovnaya, Vladimir Makarov, Renzo G. DiNatale, Kyle A. Blum, Xiaoxiao Ma, Diego Chowell, Ming O. Li, David B. Solit, Scott W. Lowe, Timothy A. Chan, Robert J. Motzer, Martin H. Voss, A. Ari Hakimi
Publikováno v:
Cancer Discov
It is poorly understood how the tumor immune microenvironment influences disease recurrence in localized clear-cell renal cell carcinoma (ccRCC). Here we performed whole-transcriptomic profiling of 236 tumors from patients assigned to the placebo-onl
Autor:
A. Ari Hakimi, Martin H. Voss, Robert J. Motzer, Timothy A. Chan, Scott W. Lowe, David B. Solit, Ming O. Li, Diego Chowell, Xiaoxiao Ma, Kyle A. Blum, Renzo G. DiNatale, Vladimir Makarov, Irina Ostrovnaya, Brandon J. Manley, Ed Reznik, Jonathan Coleman, Paul Russo, Ying-Bei Chen, John Millholland, Alexander Savchenko, Albert Reising, Mahtab Marker, Mahdi Golkaram, Eduardo A. Mascareno, Andrew W. Silagy, Anders E. Berglund, Ming Liu, Briana G. Nixon, Hui Jiang, Erich Sabio, Fengshen Kuo, Michael Curry, Nicholas H. Chakiryan, Josef Leibold, Lynda Vuong, Phillip M. Rappold
It is poorly understood how the tumor immune microenvironment influences disease recurrence in localized clear-cell renal cell carcinoma (ccRCC). Here we performed whole-transcriptomic profiling of 236 tumors from patients assigned to the placebo-onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af22d74b1526aba432a0f069b99d41d9
https://doi.org/10.1158/2159-8290.c.6549733.v1
https://doi.org/10.1158/2159-8290.c.6549733.v1
Autor:
A. Ari Hakimi, Martin H. Voss, Robert J. Motzer, Timothy A. Chan, Scott W. Lowe, David B. Solit, Ming O. Li, Diego Chowell, Xiaoxiao Ma, Kyle A. Blum, Renzo G. DiNatale, Vladimir Makarov, Irina Ostrovnaya, Brandon J. Manley, Ed Reznik, Jonathan Coleman, Paul Russo, Ying-Bei Chen, John Millholland, Alexander Savchenko, Albert Reising, Mahtab Marker, Mahdi Golkaram, Eduardo A. Mascareno, Andrew W. Silagy, Anders E. Berglund, Ming Liu, Briana G. Nixon, Hui Jiang, Erich Sabio, Fengshen Kuo, Michael Curry, Nicholas H. Chakiryan, Josef Leibold, Lynda Vuong, Phillip M. Rappold
Supplementary Figure from A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1ec763b13cff9a6658602529674209
https://doi.org/10.1158/2159-8290.22541734.v1
https://doi.org/10.1158/2159-8290.22541734.v1
Autor:
Angela Yoo, Cerise Tang, Mark Zucker, Kelly Fitzgerald, Renzo G. DiNatale, Phillip M. Rappold, Kate Weiss, Benjamin Freeman, Chung-Han Lee, Nikolaus Schultz, Robert Motzer, Paul Russo, Jonathan Coleman, Victor E. Reuter, Ying-Bei Chen, Maria I. Carlo, Anthony J. Gill, Ritesh R. Kotecha, A. Ari Hakimi, Ed Reznik
Publikováno v:
European urology focus. 8(5)
Succinate dehydrogenase-deficient and fumarate hydratase-deficient renal cell carcinomas (SDHRCC and FHRCC) are rare kidney cancers driven by loss of TCA cycle enzymes.To define and compare the genomic and metabolomic hallmarks of SDHRCC and FHRCC.We
Autor:
Andrew Chang, Phillip Spiess, Brandon J. Manley, Daniel Jeong, Jad Chahoud, Phillip Altrock, Jamie K. Teer, James J. Mulé, Anders Berglund, Daryoush Saeed-Vafa, Jonathan Nguyen, Carlos Moran, Phillip M Rappold, Esther Katende, A. Ari Hakimi, Gregory J. Kimmel, Michelle Fournier, Nicholas H. Chakiryan, Neale Lopez-Blanco, Liang Wang, Jasreman Dhillon, Dongliang Du, Young-Chul Kim, Ali Hajiran
We performed multiplex immunofluorescence (mIF) using an array of myeloid and lymphoid markers on primary tumor samples from 122 patients with RCC. Regions of interest (ROIs) were selected from three distinct tumor zones: the tumor-core, stroma, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::376aae6a0e66cd6a255403394b8cc843
https://doi.org/10.21203/rs.3.rs-847697/v1
https://doi.org/10.21203/rs.3.rs-847697/v1
Autor:
A. Ari Hakimi, Martin H. Voss, Robert J. Motzer, Timothy A. Chan, Ed Reznik, Satish K. Tickoo, Jonathan A. Coleman, Paul Russo, Phillip M Rappold, Fengshen Kuo
Publikováno v:
Journal of Urology. 206
Autor:
Benjamin A Freeman, Maria I. Carlo, A. Ari Hakimi, Ritesh Kotecha, Kelly Fitzgerald, Ed Reznik, Cerise Tang, Kate Weiss, Angela Yoo, Chung-Han Lee, Phillip M Rappold, Mark Zucker
Publikováno v:
Journal of Urology. 206
INTRODUCTION AND OBJECTIVE:Mutations in TCA cycle enzymes succinate dehydrogenase (SDH) and fumarate hydratase (FH) are associated with rare kidney cancers. However, the molecular features of SDH-d...
Autor:
Phillip M Rappold, Martin H. Voss, Ying-Bei Chen, Kate Weiss, A. Ari Hakimi, Ed Reznik, Satish K. Tickoo, Paul Russo, Angela Yoo, Robert J. Motzer, Jonathan A. Coleman, Benjamin Davelman, Mark Zucker, Timothy A. Chan
Publikováno v:
Journal of Urology. 206
INTRODUCTION AND OBJECTIVE:Angiomyolipomas (AMLs) are the most common benign renal neoplasm with a strong female predilection, and occur as sporadic, isolated entities in the majority of cases. Amo...