Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Phillip L. Hagan"'
Publikováno v:
European Journal of Nuclear Medicine. 19
This study was conducted to investigate alterations that occur in an indium/111 Fab′ of a monoclonal antibody following its in vivo administration. Patients were infused with 111 In-Fab′ of the monoclonal antibody ZCE-025. Serum and urine specime
Autor:
Samuel E. Halpern, Amox D, Perdikakis B, B Merchant, Dillman Ro, Schweighardt S, Burks R, J.M. Frincke, Phillip L. Hagan, J.B. Dillman
Publikováno v:
Archives of Surgery. 127:1094
• Even with the advancement of radiologic techniques, metastatic cancers can still be difficult to detect. In this study, 48 patients suspected of having occult metastases were studied by radioimmunodetection following the administration of 92.5 to
Publikováno v:
The International Journal of Applied Radiation and Isotopes. 27:615-620
A method for the iodination of tetracycline is presented which yields >85% labeling efficiency. The product is stable for a minimum of 72 hr and appears to retain tetracycline-like properties when studied in vivo . The critical factors in the synthes
Publikováno v:
Investigative Radiology. 13:40-45
The distribution of carrier-free /sup 203/Pb-acetate, /sup 203/HgCl/sub 2/, /sup 57/Cocl/sub 2/, /sup 137/CsCl and /sup 201/TlCl was investigated in rats bearing thigh-implanted Morris 7777 hepatomas. Viable and nonviable tumor tissue was collected i
Publikováno v:
Investigative Radiology. 16:120-125
Attempts were made to increase the viable tumor concentration of 54Mn and 67Ga in a rat hepatoma model by administering rat angiotensin, tolazoline, and salicylates. Salicylates increased the tumor concentrations of 54Mn and improved 65Mn viable tumo
Publikováno v:
Investigative Radiology. 15:496-501
The smallest quantity of carrier Ga and Mn necessary to initiate and maximize a carrier effect was studied in the Morris 7777 rat hepatoma model. The quantity needed for a maximum response did not appear to adversely effect the rats. Not all tissues
Publikováno v:
European Journal of Nuclear Medicine. 2:225-230
The tissue distribution of Sc-46, Mn-54, Zn-65, In-111 and Au-195 were studied in a rat hepatoma model at various time intervals over a 96 h period. The tumor localizing properties of these isotopes were evaluated by examining their incorporation and
Publikováno v:
Investigative Radiology. 16:229-233
The intravenous administration of Fe+3 -citrate (1.6 mg/kg body weight) was demonstrated to alter the concentration of carrier-free 67Ga and 54Mn in malignant and healthy tissues of the rat, Morris 7777 hepatoma model. When the Fe+3 was injected 2 ho
Autor:
Samuel E. Halpern, J Beauregard, B Merchant, C Mongovi, M L Clutter, Amox D, M Unger, Richard M. Bartholomew, Phillip L. Hagan, W Haindl
Publikováno v:
Radiology. 168(2)
The purpose of this study was to evaluate and compare the kinetics, biodistribution, and tumor-depicting properties of three intact indium-111-labeled murine monoclonal antibodies (MoAb) and to determine if use of In-111-labeled F(ab')2 fragments of
Publikováno v:
Radiology. 120(3)
The relative effects of selective intra-arterial and intravenous infusions of vasopressin were evaluated in 16 normotensive dogs. One group was infused via the left gastric artery, one was infused via a peripheral vein, and a control group was not in