Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Phillip L. Evans"'
1
The synthesis and evaluation of peptidyl aspartyl aldehydes as inhibitors of ice
Autor: Phillip L. Evans, Saroop S. Matharu, Scott A. Raybuck, David Kay, Yu-Ping Luong, Lauffer David J, Murcko Mark A, David J. Livingston, Mullican Michael D, Golec Julian M C, Roger John Gillespie, Geoffrey M. Porritt
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 4:2359-2364
The tetrapeptide aldehyde Ac-Tyr-Val-Ala-AspH ( 1 , L-709,049) has been reported to be a potent reversible inhibitor of Interleukin-1β Converting Enzyme (ICE). We have prepared a series of analogs of 1 , in order to explore the active sige of ICE. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab93ad698808a5cf3b6d4bee3e5c5c3d
https://doi.org/10.1016/0960-894x(94)85040-2
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2
Directed Homogeneous Hydrogenation: Methylanti-3-Hydroxy-2-Methylpentanoate
Autor: Phillip L. Evans, A. P. James, John M. Brown
Publikováno v: Organic Syntheses
Directed homogeneous hydrogenation: methyl anti-3-hydroxy-2-methylpentanoate product: Bicyclo[2.2.1]hepta-2,5-diene 1,4-bis(diphenylphosphino)butanerhodium tri-fluoromethanesulfonate reactant: bicyclo[2.2.1]hepta-2,5-diene-2,4-pentanedionatorhodium (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::625c3c1629f154fde90f57201fad0197
https://doi.org/10.1002/0471264180.os068.09
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3
Stereochemical course of hydrogen addition to bis[(S,S-2,3-bis(diphenylphosphino)butane]iridium(I). Crystal structure of dihydrogen bis[(S,S)-2,3-bis(diphenylphosphino)butanel]-iridium(I) tetrafluoroborate
Autor: Peter J. Maddox, Phillip L. Evans, Kevin H. Sutton, John M. Brown
Publikováno v: Journal of Organometallic Chemistry. 359:115-125
Addition of H 2 to bis( S,S )-2,3-bis(diphenylphosphino)butaneiridium(I) tetrafluoroborate gives a single stereoisomer, whose crystal structure has been determined. Crystal data for C 56 H 58 BF 4 IrP 4 : orthorhombic space group, P 2 1 2 1 2 1 , a 1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f593d657bbd4ffa7029bbc9185a3990
https://doi.org/10.1016/0022-328x(89)85257-x
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4
Phosphinosulphoxide rhodium complexes. Synthesis, crystal structure, and catalytic chemistry of [(2,3,5,6-η)-bicyclo[2.2.1]-hepta-2,5-diene][P,O-diphenyl(phenylsulphinylmethyl)-phosphine]rhodium(I) trifluoromethanesulphonate and asymmetric analogues
Autor: Nathaniel W. Alcock, Phillip L. Evans, John M. Brown
Publikováno v: Journal of Organometallic Chemistry. 356:233-247
α-Phosphinosulphoxides are readily accessible by the reaction of α-lithioalkylsulphoxides with Ph2PCl, and are stable towards internal oxygen transfer when pure. The compound Ph2PCH2S(O)Ph thus prepared was shown to form a cationic rhodium bicyclo[
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6bf4dcd1201d7e9f78b7910c2c5f6308
https://doi.org/10.1016/0022-328x(88)83094-8
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6
Stereochemistry of intermediates in homogeneous hydrogenation catalysed by tristriphenylphosphinerhodium chloride, employing nuclear magnetic resonance magnetisation transfer
Autor: Andrew R. Lucy, John M. Brown, Phillip L. Evans
Publikováno v: Journal of the Chemical Society, Perkin Transactions 2. :1589
The DANTE technique has been employed to observe intra- and inter-molecular exchange equilibria in Wilkinson's catalyst, ClRh(PPh3)3 and its dihydride. The parent compound undergoes automerisation much faster than dissociative exchange with free PPh3
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa44ba63cfa6c28195373351c03c0715
https://doi.org/10.1039/p29870001589
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