Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Phillip J. Monaghan"'
Autor:
Margherita Carucci, Andrew Clamp, Cong Zhou, Chris Hurt, Rosalind Glasspool, Phillip J. Monaghan, Sally Thirkettle, Michael Wheatley, Madia Mahmood, Monica Narasimham, Tracy Cox, Hilary Morrison, Susan Campbell, Annmarie Nelson, Daniella Holland-Hart, Noreen Hopewell-Kelly, Abin Thomas, Catharine Porter, Magdalena Slusarczyk, Alys Irving, Caroline Dive, Richard Adams, Gordon C. Jayson
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Anti-angiogenic, VEGF inhibitors (VEGFi) increase progression-free survival (PFS) and, in some cases, overall survival in many solid tumours. However, their use has been compromised by a lack of informative biomarkers. We have sho
Externí odkaz:
https://doaj.org/article/2cb2b6eb4c584bf9a3d37059d285edbd
Autor:
Sally Thirkettle, Patrycja Blaszczyk, Rachel Evans, Michael Wheatley, Madihah Abbas, Joanne Russell, Phillip J Monaghan
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 60:212-216
Background There is limited published data on the stability of calcitonin, chromogranin A, thyroglobulin and anti-thyroglobulin antibodies in serum. The aim of this study was to determine stability at three temperature conditions over 7 days, reflect
Autor:
Anil Bhansali, Naresh Sachdeva, Ashu Rastogi, Phillip J. Monaghan, Arun Kumar Aggarwal, KV Ravi Teja, Pinaki Dutta, Rimesh Pal, Sanjay Kumar Bhadada, Dewan G, Bhanu Malhotra, Márta Korbonits, Liza Das, Ram Kumar Marwaha, Peter J Trainer, Rama Walia
Publikováno v:
Endocrine Abstracts.
Autor:
Phillip J. Monaghan, Lieselotte Lennartz, Christa M. Cobbaert, Andrew St John, Patrick M.M. Bossuyt, Andrea R. Horvath, Ralf Röddiger, Cecilia Gelfi, Sverre Sandberg, Maurice O'Kane, Sarah J. Lord
Publikováno v:
Annals of clinical biochemistry, 56(5), 527-535. SAGE Publications Ltd
Annals of Clinical Biochemistry, 56(5), 527-535
Annals of Clinical Biochemistry, 56(5), 527-535
Background Biomarker discovery studies often claim ‘promising’ findings, motivating further studies and marketing as medical tests. Unfortunately, the patient benefits promised are often inadequately explained to guide further evaluation, and few
Autor:
Safwaan Adam, Brian G. Keevil, Anna-Elisabeth Minder Steimer, Suzanne Meredith, Megan Elizabeth Manson, Anne White, Peter J Trainer, Claire E Higham, Elizabeth Cottrell, Noor Rafhati Adyani Abdullah, Phillip J. Monaghan
Publikováno v:
Journal of the Endocrine Society
Introduction: Salivary glucocorticoids (cortisol [SalF], cortisone [SalE]) are collected non-invasively, unaffected by variation in cortisol binding globulin (CBG) and an established tool in the investigation of Cushing’s syndrome (CS). We have pre
Autor:
Samar Kulkarni, Sarah Wilson, Joanne Russell, Phillip J. Monaghan, Jim Cavet, Sally Thirkettle, Tasneem Ganijee
Publikováno v:
Annals of clinical biochemistry. 57(2)
Background The novel daratumumab immunotherapy is a human IgG1 kappa antibody targeted against CD38, which is almost universally expressed on myeloma plasma cells. Daratumumab has efficacy in clinical trials for the treatment of multiple myeloma; how
Publikováno v:
Annals of clinical biochemistry. SAGE Publications Ltd
Autor:
Claire E Higham, Anne C Armstrong, Phillip J. Monaghan, Brian G. Keevil, Zena Salih, Sacha J Howell, Laura Owen
Publikováno v:
British Journal of Cancer
Biochemical evaluation of menopausal status is used to inform treatment decisions, including clinical trial eligibility in women with oestrogen receptor positive breast cancer. However, fulvestrant may interfere with oestradiol immunoassays and confo
Autor:
Joanne E Adaway, Phillip J. Monaghan, Annmarie Miller, Brian G. Keevil, Laura Owen, Nicola Merrett
Publikováno v:
Annals of clinical biochemistry. 57(1)
Objective Sex hormone-binding globulin (SHBG) is a glycoprotein which binds hormones such as testosterone. Around 97% of circulating testosterone is bound to SHBG or albumin and is therefore biologically unavailable; 2–3% of testosterone is free. F
Autor:
Cameron T. Whitley, Richard Cathomas, Claire M. Connell, Peter Wilson, Tobias Janowitz, Tamer Al-Sayed, Harry Potts, Helena M. Earl, Michael J. Dooley, Ian Beh, James M.J. Weaver, Gianfilippo Bertelli, Duncan I. Jodrell, Simon Tavaré, Martin Fehr, Edward H. Williams, Andy G. Lynch, Phillip J. Monaghan, Michael A. Bookman, Nicholas J. Bird, Amy Quinton, Paul D. Lewis, Susan Poole, Jonathan Shamash, Patrick B. Mark
Publikováno v:
JNCI Cancer Spectrum
This work was supported by Cancer Research UK (EHW, TJ: C42738/A24868); National Institute of Health Research Cambridge Biomedical Research Centre (HE); National Institute of Health Research UK Academic Clinical Fellowship (CMC); and National Institu