Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Phillip J. Fiore"'
Autor:
Jotham Wadsworth Coe, Phillip J. Fiore, Ian Edmonds, Jeffrey B. Sperry, Wiglesworth Kristin, Eugene Lvovich Piatnitski Chekler, Jonathan Langille, David C. Boyles, Roberta Louise Dorow, David B. Damon
Publikováno v:
Organic Process Research & Development. 18:1752-1758
This work describes the optimization and scale-up of a Buchwald–Hartwig amination reaction for the preparation of a pharmaceutical intermediate. This C–N bond formation is challenged by the use of a chiral primary amine, which both adds cost and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::470ba14d178fb0c8d303c2bfa1cd4ece
https://doi.org/10.1021/op5002319
https://doi.org/10.1021/op5002319
Publikováno v:
Organic Process Research & Development. 2:151-156
A manufacturing process to prepare two antiretroviral agents that denature the HIV-1 nucleocapsid protein (NCp7) has been developed and demonstrated on a pilot scale. 2,2‘-Dithiobis(benzoyl chloride) (4), prepared from commercially available 2,2‘
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec8b1ba648b6f0111b0095a87293f647
https://doi.org/10.1021/op9701191
https://doi.org/10.1021/op9701191
Publikováno v:
Organic Process Research & Development. 1:137-148
A manufacturing process to prepare the ACAT inhibitor 2,6-diisopropylphenyl [(2,4,6-triisopropylphenyl)acetyl]sulfamate (1; CI-1011) has been developed and successfully demonstrated on a pilot scale. Commercially available 1,3,5-triisopropylbenzene (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1524bd5da404387d73a705fdcbe13ee1
https://doi.org/10.1021/op9600419
https://doi.org/10.1021/op9600419
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b5f150c9f6b536a24fad712d26a39e4
https://doi.org/10.1002/chin.199738126
https://doi.org/10.1002/chin.199738126
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3743338e2d415d8e3b9ed7d9a54d34f2
https://doi.org/10.1002/chin.199842127
https://doi.org/10.1002/chin.199842127
Autor:
Phillip J. Fiore, James G. Davidson
Publikováno v:
Nucleosides and Nucleotides. 10:1477-1483
A direct and efficient synthesis of 5′-deoxy-2′,3′-O-isopropylideneinosine, 7, from readily available inosine is described. An example of a potentially general synthesis of N -substituted-5′-deoxyadenosines from 7 is also described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::997d34635924c6bc080e4a866befdd95
https://doi.org/10.1080/07328319108046676
https://doi.org/10.1080/07328319108046676
Autor:
Davidson, James G., Fiore, Phillip J.
Publikováno v:
Nucleosides & Nucleotides; Oct1991, Vol. 10 Issue 7, p1477-1483, 7p