Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Phillip J, Robinson"'
Autor:
Anmin Jiang, Kye Kudo, Rachel S. Gormal, Sevannah Ellis, Sikao Guo, Tristan P. Wallis, Shanley F. Longfield, Phillip J. Robinson, Margaret E. Johnson, Merja Joensuu, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Endocytosis requires a coordinated framework of molecular interactions that ultimately lead to the fission of nascent endocytic structures. How cytosolic proteins such as dynamin concentrate at discrete sites that are sparsely distributed ac
Externí odkaz:
https://doaj.org/article/417850cc6c004c93857d76a6f63cbd31
Autor:
Elizabeth A. Connolly, Peter S. Grimison, Lisa G. Horvath, Phillip J. Robinson, Roger R. Reddel
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Sarcoma is a rare and complex disease comprising over 80 malignant subtypes that is frequently characterized by poor prognosis. Challenges in clinical management include uncertainties in diagnosis and disease classification, limited prognostic and pr
Externí odkaz:
https://doaj.org/article/ac995c1cdc4c44b3bedb06302910ae0c
Autor:
Cedric S. Tremblay, Sung Kai Chiu, Jesslyn Saw, Hannah McCalmont, Veronique Litalien, Jacqueline Boyle, Stefan E. Sonderegger, Ngoc Chau, Kathryn Evans, Loretta Cerruti, Jessica M. Salmon, Adam McCluskey, Richard B. Lock, Phillip J. Robinson, Stephen M. Jane, David J. Curtis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
The tumour microenvironment provides signals to support leukaemic stem cells (LSC) maintenance and chemoresistance. Here, the authors show that disrupting niche-associated signalling by inhibiting receptor-mediated endocytosis with a dynamin GTPase i
Externí odkaz:
https://doaj.org/article/9f9ae7f5fae34540a33d8cb9dbda1467
Autor:
Rebecca C. Poulos, Peter G. Hains, Rohan Shah, Natasha Lucas, Dylan Xavier, Srikanth S. Manda, Asim Anees, Jennifer M. S. Koh, Sadia Mahboob, Max Wittman, Steven G. Williams, Erin K. Sykes, Michael Hecker, Michael Dausmann, Merridee A. Wouters, Keith Ashman, Jean Yang, Peter J. Wild, Anna deFazio, Rosemary L. Balleine, Brett Tully, Ruedi Aebersold, Terence P. Speed, Yansheng Liu, Roger R. Reddel, Phillip J. Robinson, Qing Zhong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Clinical proteomics critically depends on the ability to acquire highly reproducible data over an extended period of time. Here, the authors assess reproducibility over four months across different mass spectrometers and develop a computational appro
Externí odkaz:
https://doaj.org/article/f31d48fe5cbd4e4fb32261099a109959
Autor:
Fiona M. Deane, Andrew J. S. Lin, Peter G. Hains, Sarah L. Pilgrim, Phillip J. Robinson, Adam McCluskey
Publikováno v:
ACS Omega, Vol 2, Iss 7, Pp 3828-3838 (2017)
Externí odkaz:
https://doaj.org/article/13b7928be0ea4fb1904544dc5a3aab77
Autor:
Kasper Engholm-Keller, Ashley J Waardenberg, Johannes A Müller, Jesse R Wark, Rowena N Fernando, Jonathan W Arthur, Phillip J Robinson, Dirk Dietrich, Susanne Schoch, Mark E Graham
Publikováno v:
PLoS Biology, Vol 17, Iss 3, p e3000170 (2019)
Depolarization of presynaptic terminals stimulates calcium influx, which evokes neurotransmitter release and activates phosphorylation-based signalling. Here, we present the first global temporal profile of presynaptic activity-dependent phospho-sign
Externí odkaz:
https://doaj.org/article/87d130e280a94c8592c007614a3e681c
Autor:
Phillip J. Robinson, Adam McCluskey, Terence J. O'Brien, Jennette Sakoff, Andrew Morokoff, Kelly A. Young, Christopher P. Gordon, Nigel C. Jones, Jayne Gilbert, Maggie P.C. Ma, Hui Lau, Anna Mariana, Swetha Perera, Megan Chircop
PDF file - 4821K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e50e04b41f63d4bc26d1d8d8853a02e
https://doi.org/10.1158/1535-7163.22496692
https://doi.org/10.1158/1535-7163.22496692
Autor:
Phillip J. Robinson, Adam McCluskey, Terence J. O'Brien, Jennette Sakoff, Andrew Morokoff, Kelly A. Young, Christopher P. Gordon, Nigel C. Jones, Jayne Gilbert, Maggie P.C. Ma, Hui Lau, Anna Mariana, Swetha Perera, Megan Chircop
PDF file - 905K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8533ad516143a6fa641cdd192b919f25
https://doi.org/10.1158/1535-7163.22496695
https://doi.org/10.1158/1535-7163.22496695
Autor:
Phillip J. Robinson, Adam McCluskey, Terence J. O'Brien, Jennette Sakoff, Andrew Morokoff, Kelly A. Young, Christopher P. Gordon, Nigel C. Jones, Jayne Gilbert, Maggie P.C. Ma, Hui Lau, Anna Mariana, Swetha Perera, Megan Chircop
Inhibitors of mitotic proteins such as Aurora kinase and polo-like kinase have shown promise in preclinical or early clinical development for cancer treatment. We have reported that the MiTMAB class of dynamin small molecule inhibitors are new antimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18bad79c96c04fa357094fe7402abeec
https://doi.org/10.1158/1535-7163.c.6535369
https://doi.org/10.1158/1535-7163.c.6535369
Autor:
Phillip J. Robinson, Adam McCluskey, Terence J. O'Brien, Jennette Sakoff, Andrew Morokoff, Kelly A. Young, Christopher P. Gordon, Nigel C. Jones, Jayne Gilbert, Maggie P.C. Ma, Hui Lau, Anna Mariana, Swetha Perera, Megan Chircop
PDF file - 130K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15de4d29d4995ef9947b535fe5519152
https://doi.org/10.1158/1535-7163.22496689
https://doi.org/10.1158/1535-7163.22496689