Zobrazeno 1 - 10
of 2 630
pro vyhledávání: '"Phillip I"'
Autor:
Barbara B. Warner, Bruce A. Rosa, I. Malick Ndao, Phillip I. Tarr, J. Philip Miller, Sarah K. England, Joan L. Luby, Cynthia E. Rogers, Carla Hall-Moore, Renay E. Bryant, Jacqueline D. Wang, Laura A. Linneman, Tara A. Smyser, Christopher D. Smyser, Deanna M. Barch, Gregory E. Miller, Edith Chen, John Martin, Makedonka Mitreva
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Health disparities are driven by underlying social disadvantage and psychosocial stressors. However, how social disadvantage and psychosocial stressors lead to adverse health outcomes is unclear, particularly when exposure begins prenatally.
Externí odkaz:
https://doaj.org/article/e02c20e1c051453987d0471351f063de
Autor:
Stephen B. Freedman, David Schnadower, Myka Estes, T. Charles Casper, Stuart L. Goldstein, Silviu Grisaru, Andrew T. Pavia, Benjamin S. Wilfond, Melissa Metheney, Kadyn Kimball, Phillip I. Tarr, On behalf of the Hyperhydration to Improve Kidney Outcomes in children with Shiga Toxin-producing E. Coli infection (HIKO-STEC) Study Team
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-26 (2023)
Abstract Background Shiga toxin-producing E. coli (STEC) infections affect children and adults worldwide, and treatment remain solely supportive. Up to 15–20% of children infected by high-risk STEC (i.e., E. coli that produce Shiga toxin 2) develop
Externí odkaz:
https://doaj.org/article/d81a4bede42a476da211035f8ed8058f
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTMicrobiome-targeting therapies have received great attention as approaches to prevent disease in infants born preterm, but their safety and efficacy remain uncertain. Here we summarize the existing literature, focusing on recent meta-analyses
Externí odkaz:
https://doaj.org/article/819088b96f1646a68f8e525aceb103ff
Autor:
Ai Zhang, David de Ángel Solá, Midnela Acevedo Flores, Lijuan Cao, Leran Wang, Josh G. Kim, Phillip I. Tarr, Barbara B. Warner, Nicolás Rosario Matos, Leyao Wang
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT The gut microbiome is a potentially important mechanism that links prenatal disaster exposures with increased disease risks. However, whether prenatal disaster exposures are associated with alterations in the infant’s gut microbiome remain
Externí odkaz:
https://doaj.org/article/c1c0fbfcc47b431d8ff0cf6315e7416d
Enteric Pathogen Testing Importance for Children with Acute Gastroenteritis: a Modified Delphi Study
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT The application of clinical diagnostics for gastroenteritis in children has implications for a broad collection of stakeholders, impacting clinical care, communicable disease control, and laboratory utilization. To support diagnostic steward
Externí odkaz:
https://doaj.org/article/9c1a5dd577fb4fa7a8955741d7c30e04
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 5, Pp 100205- (2022)
Human and animal model data show that maternal obesity promotes nonalcoholic fatty liver disease in offspring and alters bile acid (BA) homeostasis. Here we investigated whether offspring exposed to maternal obesogenic diets exhibited greater cholest
Externí odkaz:
https://doaj.org/article/658eb201c87f4a5bb9a67358818c813e
Autor:
Connie Fung, Brendan Wilding, Ralf B. Schittenhelm, Robert J. Bryson-Richardson, Phillip I. Bird
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2475 (2023)
Individuals homozygous for the Pi*Z allele of SERPINA1 (ZAAT) are susceptible to lung disease due to insufficient α1-antitrypsin secretion into the circulation and may develop liver disease due to compromised protein folding that leads to inclusion
Externí odkaz:
https://doaj.org/article/d41c267b61bf47928fdc2ad0077fda34
Autor:
Claudia Cantoni, Qingqi Lin, Yair Dorsett, Laura Ghezzi, Zhongmao Liu, Yeming Pan, Kun Chen, Yanhui Han, Zhengze Li, Hang Xiao, Matthew Gormley, Yue Liu, Suresh Bokoliya, Hunter Panier, Cassandra Suther, Emily Evans, Li Deng, Alberto Locca, Robert Mikesell, Kathleen Obert, Pamela Newland, Yufeng Wu, Amber Salter, Anne H. Cross, Phillip I. Tarr, Amy Lovett-Racke, Laura Piccio, Yanjiao Zhou
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103798- (2022)
Summary: Background: Multiple sclerosis (MS) has a complex genetic, immune and metabolic pathophysiology. Recent studies implicated the gut microbiome in MS pathogenesis. However, interactions between the microbiome and host immune system, metabolism
Externí odkaz:
https://doaj.org/article/573e7b67813f4c1d998df00724646945
Autor:
Daniel J Rawle, Thuy T Le, Troy Dumenil, Cameron Bishop, Kexin Yan, Eri Nakayama, Phillip I Bird, Andreas Suhrbier
Publikováno v:
eLife, Vol 11 (2022)
Granzyme A (GZMA) is a serine protease secreted by cytotoxic lymphocytes, with Gzma-/- mouse studies having informed our understanding of GZMA’s physiological function. We show herein that Gzma-/- mice have a mixed C57BL/6J and C57BL/6N genetic bac
Externí odkaz:
https://doaj.org/article/52beee401a264cc08b6f6799d457738e
Autor:
Rabia Maqsood, Rachel Rodgers, Cynthia Rodriguez, Scott A. Handley, I. Malick Ndao, Phillip I. Tarr, Barbara B. Warner, Efrem S. Lim, Lori R. Holtz
Publikováno v:
Microbiome, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background The earliest microbial colonizers of the human gut can have life-long consequences for their hosts. Precisely how the neonatal gut bacterial microbiome and virome are initially populated is not well understood. To better understan
Externí odkaz:
https://doaj.org/article/0f06efc122884a16a6400f3f3c608728