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pro vyhledávání: '"Phillip Hopcroft"'
Autor:
Linda Sandin, Jason Breed, Emma J. Davies, David Robinson, Clifford David Jones, Elizabeth Janet Pease, Richard A. Ward, Pei Zhang, Karen Roberts, Francis D. Gibbons, Claire Rooney, Nicola Lyndsay, Iain Simpson, Phillip Hopcroft, Vikki Flemington, Christopher G Jones
Publikováno v:
Cancer Research. 78:1856-1856
The RAS/MAPK pathway is a major driver in oncogenesis and is dysregulated in approximately 30% of human cancers, primarily by mutations in BRAF or RAS genes. While BRAF and MEK inhibitors improve BRAF mutant melanoma patient outcomes, single-agent pa