Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Phillip G. Wood"'
Autor:
Thomas Mager, David Lopez de la Morena, Verena Senn, Johannes Schlotte, Anna D´Errico, Katrin Feldbauer, Christian Wrobel, Sangyong Jung, Kai Bodensiek, Vladan Rankovic, Lorcan Browne, Antoine Huet, Josephine Jüttner, Phillip G. Wood, Johannes J. Letzkus, Tobias Moser, Ernst Bamberg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Optogenetic applications would benefit from channelrhodopsins (ChRs) with faster photostimulation, increased tissue transparency and lower phototoxicity. Here, the authors develop fast red-shifted ChR variants and show the abilities for temporal prec
Externí odkaz:
https://doaj.org/article/9c3dadccba5843fba489be7c07b640fb
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169506 (2017)
Differentiated neurons can be rapidly acquired, within days, by inducing stem cells to express neurogenic transcription factors. We developed a protocol to maintain long-term cultures of human neurons, called iNGNs, which are obtained by inducing Neu
Externí odkaz:
https://doaj.org/article/e6ca5f87c8cf4f279f3dcc0209b8b758
Autor:
Katrin Feldbauer, Jan Schlegel, Juliane Weissbecker, Frank Sauer, Phillip G Wood, Ernst Bamberg, Ulrich Terpitz
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165344 (2016)
An optochemokine tandem was developed to control the release of calcium from endosomes into the cytosol by light and to analyze the internalization kinetics of G-protein coupled receptors (GPCRs) by electrophysiology. A previously constructed rhodops
Externí odkaz:
https://doaj.org/article/4acc6269d1ad45c88207e5c5294242fc
Autor:
Virginia Helena Albarracín, Ivana Kraiselburd, Christian Bamann, Phillip G Wood, Ernst Bamberg, María Eugenia Farias, Wolfgang Gärtner
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154962 (2016)
The sequenced genome of the poly-extremophile Exiguobacterium sp. S17, isolated from modern stromatolites at Laguna Socompa (3,570 m), a High-Altitude Andean Lake (HAAL) in Argentinean Puna revealed a putative proteorhodopsin-encoding gene. The HAAL
Externí odkaz:
https://doaj.org/article/eb8afab62d424dbf8a69ef4c11c04b2d
Autor:
SangYong Jung, Antoine Huet, Christian Wrobel, Tobias Moser, Kai Bodensiek, Vladan Rankovic, Johannes Schlotte, Thomas Mager, Ernst Bamberg, Lorcan Browne, Katrin Feldbauer, Anna D´Errico, David Lopez de la Morena, Johannes J. Letzkus, Phillip G. Wood, Verena Senn, Josephine Jüttner
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Optogenetics revolutionizes basic research in neuroscience and cell biology and bears potential for medical applications. We develop mutants leading to a unifying concept for the construction of various channelrhodopsins with fast closing kinetics. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519104d74a27e3249ef123f4a7e8c2d1
https://doi.org/10.1038/s41467-018-04146-3
https://doi.org/10.1038/s41467-018-04146-3
Publikováno v:
Journal of Molecular Biology.
Ca 2 + concentration jumps for the activation of Ca 2 + -dependent ion channels or transporters can be obtained either by fast solution exchange or by the use of caged Ca 2 + . Here, we report on an alternate optogenetic method for the activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2618edb8bf3f36050136981c313784dc
Autor:
Ulrich Terpitz, Ernst Bamberg, Jan Schlegel, Frank Sauer, Juliane Weissbecker, Katrin Feldbauer, Phillip G. Wood
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0165344 (2016)
PLoS ONE, Vol 11, Iss 10, p e0165344 (2016)
An optochemokine tandem was developed to control the release of calcium from endosomes into the cytosol by light and to analyze the internalization kinetics of G-protein coupled receptors (GPCRs) by electrophysiology. A previously constructed rhodops
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf7260a648859403d584a0ab79c969c
http://publikationen.ub.uni-frankfurt.de/files/41992/container.zip
http://publikationen.ub.uni-frankfurt.de/files/41992/container.zip
Publikováno v:
Journal of molecular biology. 429(6)
Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eabdfac86ef8f30f27695dae928491d8
https://pubmed.ncbi.nlm.nih.gov/28192090
https://pubmed.ncbi.nlm.nih.gov/28192090
Autor:
Christian Bamann, Heike Fotis, Ernst Bamberg, Robert E. Dempski, Katrin Feldbauer, Phillip G. Wood, Sonja Kleinlogel
Publikováno v:
Nature Neuroscience. 14:513-518
In this Technical Report, Kleinlogel and colleagues created and characterized a new channelrhodopsin-2 mutant with an enhanced permeability to calcium. Dubbed CatCh (calcium translocating channelrhodopsin), this new variant's enhanced calcium permeab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b48e48eebd6b54c2bb27b32e85d6f905
https://doi.org/10.1038/nn.2776
https://doi.org/10.1038/nn.2776
Autor:
Martin Brauner, Jana F. Liewald, Alexander Gottschalk, Georg Nagel, Ernst Bamberg, Natalie Watzke, Liping Wang, Kenneth Kay, Karl Deisseroth, Phillip G. Wood, Feng Zhang
Publikováno v:
Nature. 446:633-639
Our understanding of the cellular implementation of systems-level neural processes like action, thought and emotion has been limited by the availability of tools to interrogate specific classes of neural cells within intact, living brain tissue. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6bdd967c43388dddc14307039479bb
https://doi.org/10.1038/nature05744
https://doi.org/10.1038/nature05744