Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Phillip G. Montgomery"'
Autor:
James M. McFarland, Zandra V. Ho, Guillaume Kugener, Joshua M. Dempster, Phillip G. Montgomery, Jordan G. Bryan, John M. Krill-Burger, Thomas M. Green, Francisca Vazquez, Jesse S. Boehm, Todd R. Golub, William C. Hahn, David E. Root, Aviad Tsherniak
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Integrated analyses of multiple large-scale screenings can be complicated by batch effects and technical artefacts. McFarland et al. introduce DEMETER2, a hierarchical model coupled with model-based normalization, which allows the assessment of diffe
Externí odkaz:
https://doaj.org/article/d0eb361d0bb14b90ba18bfe3b6bb1fd5
Autor:
William C. Hahn, Aviad Tsherniak, Jesse S. Boehm, Francisca Vazquez, John M. Krill-Burger, Thomas M Green, Jordan Bryan, Guillaume Kugener, James M. McFarland, Todd R. Golub, Joshua M. Dempster, David E. Root, Zandra V. Ho, Phillip G. Montgomery
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
The availability of multiple datasets comprising genome-scale RNAi viability screens in hundreds of diverse cancer cell lines presents new opportunities for understanding cancer vulnerabilities. Integrated analyses of these data to assess differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e2e2e77e987d02e05195c1bd9da7df
Autor:
Zohra Kalani, Han Xu, Jesse S. Boehm, Sasha Pantel, Aviad Tsherniak, William F. Harrington, Jaime J. Chang, Rakela Lubonja, Michael Okamoto, Levi D. Ali, William C. Hahn, Francisca Vazquez, Todd R. Golub, Guozhi Jiang, Neekesh V. Dharia, Ann E. Sizemore, Barbara A. Weir, Amy Goodale, Derek C. Hawes, Robin M. Meyers, Phillip G. Montgomery, Yenarae Lee, Matthew Strickland, James M. McFarland, Jordan Bryan, Victor A. Zhivich, Glenn S. Cowley, Ting Wu, David E. Root, Meghan R. Wyatt
The CRISPR-Cas9 system has revolutionized gene editing both on single genes and in multiplexed loss-of-function screens, enabling precise genome-scale identification of genes essential to proliferation and survival of cancer cells. However, previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4e347b4c3869dec32a0a652b97f78e
Autor:
Barbara A. Weir, Kimberly Stegmaier, Neekesh V. Dharia, David E. Root, Guozhi Jiang, James M. McFarland, Jordan Bryan, Meghan R. Wyatt, Jesse S. Boehm, Victor A. Zhivich, Robin M. Meyers, Phillip G. Montgomery, Matthew Strickland, Jaime J. Chang, Glenn S. Cowley, Todd R. Golub, Yenarae Lee, Aviad Tsherniak, Rakela Lubonja, William F. Harrington, Francisca Vazquez, Amy Goodale, Derek C. Hawes, Levi D. Ali, Zohra Kalani, Michael Okamoto, William C. Hahn, Han Xu, Ann E. Sizemore, Ting Wu, Sasha Pantel
Publikováno v:
Nature genetics. 49(12)
The CRISPR-Cas9 system has revolutionized gene editing both at single genes and in multiplexed loss-of-function screens, thus enabling precise genome-scale identification of genes essential for proliferation and survival of cancer cells. However, pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a3d3d161f01179ea7001810a971589
https://pubmed.ncbi.nlm.nih.gov/29186130
https://pubmed.ncbi.nlm.nih.gov/29186130