Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Phillip G. Mattingly"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:2407-2410
Hydrogen peroxide generated from the enzymatic oxidation of choline was detected using a chemiluminescent acridinium-9-carboxamide. The dose-response for choline (0-50 microM) was established in buffer and was applicable to the quantification of chol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39da6d2a97863a1767316c7944f996ce
https://doi.org/10.1016/j.bmcl.2006.01.114
https://doi.org/10.1016/j.bmcl.2006.01.114
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:3917-3921
Two cyanocobalamin– N -sulfonyl-acridinium-9-carboxamides with linkage through the N 10 or 9-position were prepared from B 12 -e-carboxylic acid. The noncovalent association of intrinsic factor with these ligands resulted in specific modulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b3fe6569b80c2f142c098441b63026
https://doi.org/10.1016/j.bmcl.2004.05.062
https://doi.org/10.1016/j.bmcl.2004.05.062
Publikováno v:
Tetrahedron. 59:5749-5761
A total of 11 novel phosphoramidites, 3a – d , 4a – d and 14a – c were prepared from 2′-deoxyuridine functionalized at 5 and 6-position of the pyrimidine ring with hapten reporter groups, e.g. adamantane, carbazole, dansyl and dabsyl, suitabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64c5e68158bd3bdeaba3b20dc2e26c3e
https://doi.org/10.1016/s0040-4020(03)00875-5
https://doi.org/10.1016/s0040-4020(03)00875-5
Publikováno v:
Synthetic Communications. 32:3199-3205
A convenient method for the preparation of α-ketoacetal derivatives 2a–g was developed by addition of Grignard reagent (1a–g) to commercially available ethyl diethoxyacetate (3) in 60–96% yield.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::837951902bbe6be28ab11c08c6f4e90a
https://doi.org/10.1081/scc-120013744
https://doi.org/10.1081/scc-120013744
Publikováno v:
Organic Preparations and Procedures International. 33:505-514
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca93fbcb98b989568d96cc9c158ee136
https://doi.org/10.1080/00304940109356618
https://doi.org/10.1080/00304940109356618
Publikováno v:
Organic Preparations and Procedures International. 33:477-485
(2001). SYNTHESIS OF COELENTERAZINE. Organic Preparations and Procedures International: Vol. 33, No. 5, pp. 477-485.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70e7a36abadd292b287fe027c43bae14
https://doi.org/10.1080/00304940109356615
https://doi.org/10.1080/00304940109356615
Publikováno v:
Rapid Communications in Mass Spectrometry. 14:2112-2115
Addition of nucleophiles to the chemiluminescent acridinium-9-carboxamide 1 resulted in the formation of the acridan adduct 7. The relative ratio of 1/7 present in solution could be determined by electrospray ionization mass spectrometry (ESI-MS) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0ea6a3c80d04580a7aacdae68171833
https://doi.org/10.1002/1097-0231(20001130)14:22<2112::aid-rcm139>3.0.co
https://doi.org/10.1002/1097-0231(20001130)14:22<2112::aid-rcm139>3.0.co
Publikováno v:
Bioconjugate Chemistry. 10:1032-1037
Surface plasmon resonance (SPR) analysis was used to assess the immunoreactivity of anti-biotin (4) and anti-fluorescein (5) monoclonal antibody after conjugation with the N-hydroxysuccinimide ester of acridinium-9-carboxamide 1. Only minor changes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7d7692d44dbae09dc34947bd7b7559
https://doi.org/10.1021/bc990057e
https://doi.org/10.1021/bc990057e
Publikováno v:
Tetrahedron. 55:10899-10914
Acridinium salts 3a-h were synthesized from the corresponding sulfonamides 1a-h and their chemiluminescence profiles were compared. The quantity of light emitted over the time studied did not correlate well with the pKa of sulfonamide leaving group.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44c74a3a19feaf69d38cac2a6fa2d2d8
https://doi.org/10.1016/s0040-4020(99)00624-9
https://doi.org/10.1016/s0040-4020(99)00624-9
Publikováno v:
Steroids. 64:283-290
The 5 and 6-isomers of O-(fluoresceinylmethyl)hydroxylamine reacted with a representative sample of oxo-steroids (6-oxoestradiol, estrone, norethindrone, cortisol, progesterone, and digitoxin-dialdehyde) to produce O-(fluoresceinylmethyl)oxime conjug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104d1f35a6ebaa058368498cfa9170a0
https://doi.org/10.1016/s0039-128x(99)00004-5
https://doi.org/10.1016/s0039-128x(99)00004-5