Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Phillip E. Klebba"'
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
We studied the Escherichia coli outer membrane protein Fiu, a presumed transporter of monomeric ferric catecholates, by introducing Cys residues in its surface loops and modifying them with fluorescein maleimide (FM). Fiu-FM bound iron complexes of t
Externí odkaz:
https://doaj.org/article/251b280807874e81b191f2004fc73118
Autor:
Yoriko Lill, Lorne D Jordan, Chuck R Smallwood, Salete M Newton, Markus A Lill, Phillip E Klebba, Ken Ritchie
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0160862 (2016)
The important process of nutrient uptake in Escherichia coli, in many cases, involves transit of the nutrient through a class of beta-barrel proteins in the outer membrane known as TonB-dependent transporters (TBDTs) and requires interaction with the
Externí odkaz:
https://doaj.org/article/0b6af7436f2c49a4afb520b16da9efeb
Autor:
Phillip E. Klebba, Kyle J. Moore, Aritri Majumdar, Ashish Kumar, Taihao Yang, Salete M. C. Newton, Chuck R. Smallwood, Daniel C. Scott, Vy Trinh, Noah J. Long
Publikováno v:
Journal of Biological Chemistry. 295:4974-4984
The Escherichia coli outer membrane receptor FepA transports ferric enterobactin (FeEnt) by an energy- and TonB-dependent, but otherwise a mechanistically undetermined process involving its internal 150-residue N-terminal globular domain (N-domain).
Publikováno v:
The FASEB Journal. 35
Autor:
Somnath Chakravorty, Ashish Kumar, Taihao Yang, Salete M. C. Newton, David A Six, Colton Munger, Brittany L. Nairn, Phillip E. Klebba
Publikováno v:
Chem Rev
Chemical Reviews, 121 (9). pp. 5193-5239.
Chemical Reviews, 121 (9). pp. 5193-5239.
Iron is an indispensable metabolic cofactor in both pro- and eukaryotes, which engenders a natural competition for the metal between bacterial pathogens and their human or animal hosts. Bacteria secrete siderophores that extract Fe(3+) from tissues,
Autor:
Heather P McLaughlin, Qiaobin Xiao, Rosemarie B Rea, Hualiang Pi, Pat G Casey, Trevor Darby, Alain Charbit, Roy D Sleator, Susan A Joyce, Richard E Cowart, Colin Hill, Phillip E Klebba, Cormac G M Gahan
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30928 (2012)
Regulation of iron homeostasis in many pathogens is principally mediated by the ferric uptake regulator, Fur. Since acquisition of iron from the host is essential for the intracellular pathogen Listeria monocytogenes, we predicted the existence of Fu
Externí odkaz:
https://doaj.org/article/9f09dd02ca244a148d01d7f04ca92e87
Autor:
Hualiang Pi, Shari A Jones, Lynn E Mercer, Jessica P Meador, Joyce E Caughron, Lorne Jordan, Salete M Newton, Tyrrell Conway, Phillip E Klebba
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50020 (2012)
We investigated the importance of the production of catecholate siderophores, and the utilization of their iron (III) complexes, to colonization of the mouse intestinal tract by Escherichia coli. First, a ΔtonB strain was completely unable to coloni
Externí odkaz:
https://doaj.org/article/e84fd54a7f9c4b158c5cf197632bf44a
Autor:
Aritri, Majumdar, Vy, Trinh, Kyle J, Moore, Chuck R, Smallwood, Ashish, Kumar, Taihao, Yang, Daniel C, Scott, Noah J, Long, Salete M, Newton, Phillip E, Klebba
Publikováno v:
J Biol Chem
The Escherichia coli outer membrane receptor FepA transports ferric enterobactin (FeEnt) by an energy- and TonB-dependent, but otherwise a mechanistically undetermined process involving its internal 150-residue N-terminal globular domain (N-domain).
Autor:
Ashish Kumar, Aritri Majumdar, Somnath Chakravorty, Taihao Yang, Phillip E. Klebba, Sally Newton
Publikováno v:
The FASEB Journal. 33