Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Phillip DiGiacomo"'
Autor:
Ellen R. Bowen, Phillip DiGiacomo, Hannah P. Fraser, Kevin Guttenplan, Benjamin A. H. Smith, Marlene L. Heberling, Laura Vidano, Nigam Shah, Mehrdad Shamloo, Jennifer L. Wilson, Kevin V. Grimes
Publikováno v:
Discover Mental Health, Vol 3, Iss 1, Pp 1-20 (2023)
Abstract Schizophrenia is a debilitating condition necessitating more efficacious therapies. Previous studies suggested that schizophrenia development is associated with aberrant synaptic pruning by glial cells. We pursued an interdisciplinary approa
Externí odkaz:
https://doaj.org/article/3b606447bef44f88a84ab46ba8870c28
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
Alzheimer’s disease (AD) is a debilitating brain disorder that afflicts millions worldwide with no effective treatment. Currently, AD progression has primarily been characterized by abnormal accumulations of β-amyloid within plaques and phosphoryl
Externí odkaz:
https://doaj.org/article/6c7e8206e3614689b8c90af020fd845b
Autor:
Marios Georgiadis, Aileen Schroeter, Zirui Gao, Manuel Guizar-Sicairos, Marianne Liebi, Christoph Leuze, Jennifer A. McNab, Aleezah Balolia, Jelle Veraart, Benjamin Ades-Aron, Sunglyoung Kim, Timothy Shepherd, Choong H. Lee, Piotr Walczak, Shirish Chodankar, Phillip DiGiacomo, Gergely David, Mark Augath, Valerio Zerbi, Stefan Sommer, Ivan Rajkovic, Thomas Weiss, Oliver Bunk, Lin Yang, Jiangyang Zhang, Dmitry S. Novikov, Michael Zeineh, Els Fieremans, Markus Rudin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Small-angle X-ray scattering (SAXS) combines the high tissue penetration of X-rays with specificity to periodic nanostructures. The authors use SAXS tensor tomography (SAXS-TT) on intact mouse and human brain tissue samples, to quantify myelin levels
Externí odkaz:
https://doaj.org/article/35fab30941ac43ca99ab4a14e671a883
Autor:
Derek McAllister, Carolyn Akers, Brian Boldt, Lex A. Mitchell, Eric Tranvinh, David Douglas, Maged Goubran, Jarrett Rosenberg, Marios Georgiadis, Mahta Karimpoor, Phillip DiGiacomo, Nicole Mouchawar, Gerald Grant, David Camarillo, Max Wintermark, Michael M. Zeineh
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background and Purpose: Athletes participating in high-contact sports experience repeated head trauma. Anatomical findings, such as a cavum septum pellucidum, prominent CSF spaces, and hippocampal volume reductions, have been observed in cases of mil
Externí odkaz:
https://doaj.org/article/a8b388d82691495fb716ea9dd34a5a02
Autor:
Mackenzie L. Carlson, Tyler N. Toueg, M. Mehdi Khalighi, Jessa Castillo, Bin Shen, Emily C. Azevedo, Phillip DiGiacomo, Nicole Mouchawar, Gustavo Chau, Greg Zaharchuk, Michelle L. James, Elizabeth C. Mormino, Michael M. Zeineh
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Alzheimer's disease (AD) is the most common form of dementia, characterized primarily by abnormal aggregation of two proteins, tau and amyloid beta. We assessed tau pathology and white matter connectivity changes in subfields of
Externí odkaz:
https://doaj.org/article/d1ec6ce14dac4ea6bd9b4cdc12a28ec8
Autor:
Piotr Walczak, Manuel Guizar-Sicairos, Jennifer A. McNab, Marianne Liebi, Mark Augath, Michael Zeineh, Timothy M. Shepherd, Aileen Schroeter, Aleezah Balolia, Lin Yang, Markus Rudin, Marios Georgiadis, Oliver Bunk, Zirui Gao, Els Fieremans, Phillip DiGiacomo, Ivan Rajkovic, Christoph Leuze, Valerio Zerbi, Jiangyang Zhang, Dmitry S. Novikov, Benjamin Ades-Aron, Sung-Lyoung Kim, Jelle Veraart, Choong H. Lee, Thomas M. Weiss, Stefan Sommer, Gergely David, Shirish Chodankar
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, 12 (1)
Nature Communications
Nature Communications, 12 (1)
Nature Communications
Myelin insulates neuronal axons and enables fast signal transmission, constituting a key component of brain development, aging and disease. Yet, myelin-specific imaging of macroscopic samples remains a challenge. Here, we exploit myelin’s nanostruc
Publikováno v:
Magn Reson Imaging Clin N Am
High-resolution 7-T imaging and quantitative susceptibility mapping produce greater anatomic detail compared with conventional strengths because of improvements in signal/noise ratio and contrast. The exquisite anatomic details of deep structures, in
Autor:
Yitian Zeng, Brian K. Rutt, Yuanxin Chen, Donald E. Born, Maged Goubran, Hannes Vogel, Steven J. Madsen, Robert Sinclair, Michael Zeineh, Phillip DiGiacomo
Publikováno v:
Journal of Alzheimer's Disease Reports
Background: Recent evidence suggests that the accumulation of iron, specifically ferrous Fe2+, may play a role in the development and progression of neurodegeneration in Alzheimer’s disease (AD) through the production of oxidative stress. Objective
Autor:
Dan Rettmann, Timothy W. Skloss, Bryan Lanzman, Murat Aksoy, Mackenzie L. Carlson, S. Shahrukh Hashmi, Julian Maclaren, Brian K. Rutt, Phillip DiGiacomo, Jarrett Rosenberg, Ronald Dean Watkins, Brian Burns, Roland Bammer, Michael Zeineh, Elizabeth Tong
Publikováno v:
Magn Reson Med
PURPOSE: Motion artifact limits the clinical translation of high-field MR. We present an optical prospective motion correction system for 7 Tesla MRI using a custom-built, within-coil camera to track an optical marker mounted on a subject. METHODS: T
Autor:
Michael Zeineh, Jessa B. Castillo, Bin Shen, Gustavo Chau, Emily Carmen Azevedo, Tyler N. Toueg, Phillip DiGiacomo, Mackenzie L. Carlson, Michelle L. James, Nicole Mouchawar, Elizabeth C. Mormino, Mohammad Mehdi Khalighi, Greg Zaharchuk
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Introduction Alzheimer's disease (AD) is the most common form of dementia, characterized primarily by abnormal aggregation of two proteins, tau and amyloid beta. We assessed tau pathology and white matter connectivity changes in subfields of the hipp