Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Phillip Belgrader"'
Autor:
Grace X. Y. Zheng, Jessica M. Terry, Phillip Belgrader, Paul Ryvkin, Zachary W. Bent, Ryan Wilson, Solongo B. Ziraldo, Tobias D. Wheeler, Geoff P. McDermott, Junjie Zhu, Mark T. Gregory, Joe Shuga, Luz Montesclaros, Jason G. Underwood, Donald A. Masquelier, Stefanie Y. Nishimura, Michael Schnall-Levin, Paul W. Wyatt, Christopher M. Hindson, Rajiv Bharadwaj, Alexander Wong, Kevin D. Ness, Lan W. Beppu, H. Joachim Deeg, Christopher McFarland, Keith R. Loeb, William J. Valente, Nolan G. Ericson, Emily A. Stevens, Jerald P. Radich, Tarjei S. Mikkelsen, Benjamin J. Hindson, Jason H. Bielas
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Single-cell gene expression analysis is challenging. This work describes a new droplet-based single cell RNA-seq platform capable of processing tens of thousands of cells across 8 independent samples in minutes, and demonstrates cellular subtypes and
Externí odkaz:
https://doaj.org/article/9c33171e807745c7908a1e1e9a3712e3
Publikováno v:
BioTechniques, Vol 20, Iss 6, Pp 970-974 (1996)
Externí odkaz:
https://doaj.org/article/d7cfcce881fb4883a98a2023254d2922
Autor:
Pehr B. Harbury, Grace X.Y. Zheng, Solongo B. Ziraldo, Lisa E. Wagar, Tarjei S. Mikkelsen, Manuel R. Amieva, Jihang Ju, Calvin J. Kuo, Mar Margalef-Català, Jeffrey S. Glenn, Daniel J. Hart, Mark M. Davis, Arpit Batish, Caitlin E. Edwards, Ameen A. Salahudeen, Arjun Rustagi, Catherine A. Blish, Sean M. de la O, Shannon S. Choi, Monica Nagendran, Ralph S. Baric, Vincent C. Luca, Junjie Zhu, Tushar J. Desai, Khanh Nguyen, Jessica M. Terry, Tatsuya Usui, Phillip Belgrader, Ryan A. Flynn, Vincent van Unen, Chiara Sabatti, Benedict Anchang, K. Christopher Garcia, António J. M. Santos
Publikováno v:
Nature
The distal lung contains terminal bronchioles and alveoli that facilitate gas exchange and is affected by disorders including interstitial lung disease, cancer, and SARS-CoV-2-associated COVID-19 pneumonia. Investigations of these localized pathologi
Autor:
Arnold Han, Xiao Li, Solongo B. Ziraldo, Michael Snyder, Aaron J. W. Hsueh, Tarjei S. Mikkelsen, Kathryn A. Larkin, Vincent C. Luca, Julie Wilhelmy, Akifumi Ootani, Heather Ordonez, Luis A. Chia, Kelly Roelf, Mark Lee, Christopher R. Bolen, Junlei Chang, Hiroo Ueno, Calvin J. Kuo, Susan J. Henning, Paige S. Davies, Jessica M. Terry, Kelley S. Yan, Jenny Yuan, Phillip Belgrader, K. Christopher Garcia, Melissa H. Wong, Amanda T. Mah, Irving L. Weissman, Claudia Y. Janda, Grace X.Y. Zheng, Richard J. von Furstenberg
Publikováno v:
Nature. 545:238-242
The canonical Wnt/β-catenin signalling pathway governs diverse developmental, homeostatic and pathological processes. Palmitoylated Wnt ligands engage cell-surface frizzled (FZD) receptors and LRP5 and LRP6 co-receptors, enabling β-catenin nuclear
Autor:
Mar Margalef-Català, Caitlin E. Edwards, Manuel R. Amieva, Jihang Ju, Lisa E. Wagar, Arjun Rustagi, Khanh Nguyen, Vincent C. Luca, Tatsuya Usui, Ameen A. Salahudeen, Tarjei S. Mikkelsen, Shannon S. Choi, Ralph S. Baric, António J. M. Santos, Jessica M. Terry, Grace X.Y. Zheng, Mark M. Davis, Catherine A. Blish, Ryan A. Flynn, Phillip Belgrader, Solongo B. Ziraldo, Vincent van Unen, Jeffrey S. Glenn, Junjie Zhu, Sean M. de la O, Monica Nagendran, Tushar J. Desai, Calvin J. Kuo, Arpit Batish, Benedict Anchang, K. Christopher Garcia, Daniel J. Hart, Pehr B. Harbury, Chiara Sabatti
Publikováno v:
bioRxiv
Nature
Nature
The distal lung contains terminal bronchioles and alveoli that facilitate gas exchange and is affected by disorders including interstitial lung disease, cancer, and SARS-CoV-2-associated COVID-19 pneumonia. Investigations of these localized pathologi
Autor:
Rajiv Bharadwaj, Paul Wyatt, Joe Shuga, Donald A. Masquelier, Tarjei S. Mikkelsen, Mark T. Gregory, Junjie Zhu, Jerald P. Radich, Emily A. Stevens, Solongo B. Ziraldo, Christopher McFarland, Luz Montesclaros, Nolan G. Ericson, Alexander Wong, William J. Valente, Benjamin J. Hindson, Tobias Daniel Wheeler, Jason G. Underwood, H. Joachim Deeg, Jessica M. Terry, Kevin D. Ness, Phillip Belgrader, Stefanie Y. Nishimura, Geoffrey P. McDermott, Michael Schnall-Levin, Jason H. Bielas, Zachary Bent, Lan Beppu, Paul Ryvkin, Christopher Hindson, Grace X.Y. Zheng, Keith R. Loeb, Ryan Wilson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications
Characterizing the transcriptome of individual cells is fundamental to understanding complex biological systems. We describe a droplet-based system that enables 3′ mRNA counting of tens of thousands of single cells per sample. Cell encapsulation, o
Autor:
Benjamin J. Hindson, Ryan T. Koehler, John F. Regan, Alexandra Brown, Stephanie C. Tanner, Phillip Belgrader
Publikováno v:
Clinical Chemistry. 59:991-994
BACKGROUND Human epidermal growth factor receptor 2 (HER2) testing is routinely performed by immunohistochemistry (IHC) and/or fluorescence in situ hybridization (FISH) analyses for all new cases of invasive breast carcinoma. IHC is easier to perform
Autor:
Nolan G. Ericson, Alexander Wong, Keith R. Loeb, Ryan Wilson, Zachary Bent, Emily A. Stevens, Tobias Daniel Wheeler, Rajiv Bharadwaj, H. Joachim Deeg, Jessica M. Terry, William J. Valente, Jason H. Bielas, Kevin D. Ness, Phillip Belgrader, Lan Beppu, Paul Ryvkin, Tarjei S. Mikkelsen, Geoffrey P. McDermott, Jerald P. Radich, Donald A. Masquelier, Solongo B. Ziraldo, Mark T. Gregory, Luz Montesclaros, Grace X.Y. Zheng, Christopher McFarland, Paul Wyatt, Christopher Hindson, Joe Shuga, Stefanie Y. Nishimura, Benjamin J. Hindson, Michael Schnall-Levin, Junjie Zhu
Characterizing the transcriptome of individual cells is fundamental to understanding complex biological systems. We describe a droplet-based system that enables 3′ mRNA counting of up to tens of thousands of single cells per sample. Cell encapsulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7bb5ac0446559ec783467c8c0c59dd7
https://doi.org/10.1101/065912
https://doi.org/10.1101/065912
Autor:
Kelley S, Yan, Claudia Y, Janda, Junlei, Chang, Grace X Y, Zheng, Kathryn A, Larkin, Vincent C, Luca, Luis A, Chia, Amanda T, Mah, Arnold, Han, Jessica M, Terry, Akifumi, Ootani, Kelly, Roelf, Mark, Lee, Jenny, Yuan, Xiao, Li, Christopher R, Bolen, Julie, Wilhelmy, Paige S, Davies, Hiroo, Ueno, Richard J, von Furstenberg, Phillip, Belgrader, Solongo B, Ziraldo, Heather, Ordonez, Susan J, Henning, Melissa H, Wong, Michael P, Snyder, Irving L, Weissman, Aaron J, Hsueh, Tarjei S, Mikkelsen, K Christopher, Garcia, Calvin J, Kuo
Publikováno v:
Nature. 545(7653)
The canonical Wnt/β-catenin signalling pathway governs diverse developmental, homeostatic and pathological processes. Palmitoylated Wnt ligands engage cell-surface frizzled (FZD) receptors and LRP5 and LRP6 co-receptors, enabling β-catenin nuclear
Autor:
Rajiv Bharadwaj, Hanlee P. Ji, Serge Saxonov, Alex Kindwall, Melissa Luo, Patrick Marks, Clara Bermejo, Landon Merrill, Francesca Meschi, Jessica M. Terry, Adrian Fehr, John Bell, Gerard M Vurens, Kristina Giorda, Adam Lowe, Heather Ordonez, Michael Schnall-Levin, Jorge Bernate, Josephine Y Lee, Phillip Belgrader, Glenn K. Lockwood, Steven W Short, Sukhvinder Kaur, Shawn Gauby, Lawrence Greenfield, Geoffrey P. McDermott, Stephanie Greer, Pranav Patel, Andrew D. Price, Benjamin J. Hindson, Nikola O Kondov, Grace X.Y. Zheng, Sofia Kyriazopoulou-Panagiotopoulou, David E Birch, Luz Montesclaros, Alexander Wong, Kamila Belhocine, Susan M. Grimes, Ryan Wilson, Donald A. Masquelier, Patrice A Mudivarti, Kevin D. Ness, Mirna Jarosz, Adrian Chan, Indira Wu, Erik S. Hopmans, Paul Wyatt, David Stafford, Paul Hardenbol, Anthony J. Makarewicz, Joshua Delaney, Yuan Li, Zachary Bent, Christopher Hindson, Christina Wood, Keith Bjornson, Billy T. Lau, William Haynes Heaton
Publikováno v:
Nature biotechnology, vol 34, iss 3
Haplotyping of human chromosomes is a prerequisite for cataloguing the full repertoire of genetic variation. We present a microfluidics-based, linked-read sequencing technology that can phase and haplotype germline and cancer genomes using nanograms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cceca38f7f8889494f6c31fa5fc631
https://escholarship.org/uc/item/0z84g4gh
https://escholarship.org/uc/item/0z84g4gh