Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Phillip Alexander Keller Andersen"'
Autor:
Muhammad Saad Khilji, Danielle Verstappen, Tina Dahlby, Michala Cecilie Burstein Prause, Celina Pihl, Sophie Emilie Bresson, Tenna Holgersen Bryde, Phillip Alexander Keller Andersen, Kristian Klindt, Dusan Zivkovic, Marie-Pierre Bousquet-Dubouch, Björn Tyrberg, Thomas Mandrup-Poulsen, Michal Tomasz Marzec
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0222432 (2020)
A central and still open question regarding the pathogenesis of autoimmune diseases, such as type 1 diabetes, concerns the processes that underlie the generation of MHC-presented autoantigenic epitopes that become targets of autoimmune attack. Protea
Externí odkaz:
https://doaj.org/article/d6b8ef2eb2994e95bba69f26b2ed0451
Autor:
Nico Fischer, Tina Dahlby, Melissa Koomen, Thomas Mandrup-Poulsen, Charna Dibner, Volodymyr Petrenko, Phillip Alexander Keller Andersen, Seyed Mojtaba Ghiasi, Peter Horskjær Rose
Publikováno v:
International Journal of Molecular Sciences
Andersen, P A K, Petrenko, V, Rose, P H, Koomen, M, Fischer, N, Ghiasi, S M, Dahlby, T, Dibner, C & Mandrup-Poulsen, T 2021, ' Proinflammatory cytokines perturb mouse and human pancreatic islet circadian rhythmicity and induce uncoordinated β-cell clock gene expression via nitric oxide, lysine deacetylases, and immunoproteasomal activity ', International Journal of Molecular Sciences, vol. 22, no. 1, 83, pp. 1-25 . https://doi.org/10.3390/ijms22010083
International Journal of Molecular Sciences, Vol. 22, No 1 (2020) P. 83
Volume 22
Issue 1
International Journal of Molecular Sciences, Vol 22, Iss 83, p 83 (2021)
Andersen, P A K, Petrenko, V, Rose, P H, Koomen, M, Fischer, N, Ghiasi, S M, Dahlby, T, Dibner, C & Mandrup-Poulsen, T 2021, ' Proinflammatory cytokines perturb mouse and human pancreatic islet circadian rhythmicity and induce uncoordinated β-cell clock gene expression via nitric oxide, lysine deacetylases, and immunoproteasomal activity ', International Journal of Molecular Sciences, vol. 22, no. 1, 83, pp. 1-25 . https://doi.org/10.3390/ijms22010083
International Journal of Molecular Sciences, Vol. 22, No 1 (2020) P. 83
Volume 22
Issue 1
International Journal of Molecular Sciences, Vol 22, Iss 83, p 83 (2021)
Pancreatic &beta
cell-specific clock knockout mice develop &beta
cell oxidative-stress and failure, as well as glucose-intolerance. How inflammatory stress affects the cellular clock is under-investigated. Real-time recording of Per2:lucife
cell-specific clock knockout mice develop &beta
cell oxidative-stress and failure, as well as glucose-intolerance. How inflammatory stress affects the cellular clock is under-investigated. Real-time recording of Per2:lucife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f713196105e260c2898cb08ff9e574
http://europepmc.org/articles/PMC7795908
http://europepmc.org/articles/PMC7795908
Autor:
Michal Marzec, Sarah J. Richardson, Kristian Klindt, Anna Walentinsson, Marie-Pierre Bousquet, Jette Bach Agergaard, Thomas Mandrup-Poulsen, Noel G. Morgan, Phillip Alexander Keller Andersen, Tenna Holgersen Bryde, Christian Kronborg Nielsen, Tina Dahlby, Dusan Zivkovic, Muhammad Saad Khilji, Celina Pihl, Björn Tyrberg, Sophie Emilie Bresson, Danielle Verstappen
Publikováno v:
American Journal of Physiology. Endocrinology Metabolism and Gastrointestinal Physiology
American Journal of Physiology. Endocrinology Metabolism and Gastrointestinal Physiology, 2020, 318 (6), pp.e892-e900. ⟨10.1152/ajpendo.00372.2019⟩
American Journal of Physiology. Endocrinology Metabolism and Gastrointestinal Physiology, 2020, 318 (6), pp.e892-e900. ⟨10.1152/ajpendo.00372.2019⟩
Proinsulin is a misfolding-prone protein, and its efficient breakdown is critical when β-cells are confronted with high-insulin biosynthetic demands, to prevent endoplasmic reticulum stress, a key trigger of secretory dysfunction and, if uncompensat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbbc65d0d00ff0a89f988cdd60512d1
https://pubmed.ncbi.nlm.nih.gov/32255680
https://pubmed.ncbi.nlm.nih.gov/32255680
Autor:
Sophie Emilie Bresson, Kristian Klindt, Thomas Mandrup-Poulsen, Phillip Alexander Keller Andersen, Marie-Pierre Bousquet-Dubouch, Celina Pihl, Tenna Holgersen Bryde, Tina Dahlby, Dusan Zivkovic, Muhammad Saad Khilji, Michala Prause, Michal Marzec, Danielle Verstappen, Björn Tyrberg
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2020, 15 (2), pp.e0222432. ⟨10.1371/journal.pone.0222432⟩
Khilji, M S, Verstappen, D, Dahlby, T, Prause, M C B, Pihl, C, Bresson, S E, Bryde, T H, Andersen, P A K, Klindt, K, Zivkovic, D, Bousquet-Dubouch, M P, Tyrberg, B, Mandrup-Poulsen, T & Marzec, M T 2020, ' The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β ', PLoS ONE, vol. 15, no. 2, e0222432 . https://doi.org/10.1371/journal.pone.0222432
PLoS ONE, Vol 15, Iss 2, p e0222432 (2020)
PLoS ONE, Public Library of Science, 2020, 15 (2), pp.e0222432. ⟨10.1371/journal.pone.0222432⟩
Khilji, M S, Verstappen, D, Dahlby, T, Prause, M C B, Pihl, C, Bresson, S E, Bryde, T H, Andersen, P A K, Klindt, K, Zivkovic, D, Bousquet-Dubouch, M P, Tyrberg, B, Mandrup-Poulsen, T & Marzec, M T 2020, ' The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β ', PLoS ONE, vol. 15, no. 2, e0222432 . https://doi.org/10.1371/journal.pone.0222432
PLoS ONE, Vol 15, Iss 2, p e0222432 (2020)
International audience; A central and still open question regarding the pathogenesis of autoimmune diseases, such as type 1 diabetes, concerns the processes that underlie the generation of MHC-presented autoantigenic epitopes that become targets of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863383497e40a80987a92afde265bf34
https://hal-cnrs.archives-ouvertes.fr/hal-03018741/file/pone.0222432.pdf
https://hal-cnrs.archives-ouvertes.fr/hal-03018741/file/pone.0222432.pdf
