Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Phillip A. Lowe"'
Autor:
Tiia Kittilä, Patricia Calero, Folmer Fredslund, Phillip T. Lowe, David Tezé, Manuel Nieto‐Domínguez, David O’Hagan, Pablo I. Nikel, Ditte H. Welner
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 5, Pp 1622-1632 (2022)
Summary The fluorinase enzyme represents the only biological mechanism capable of forming stable C–F bonds characterized in nature thus far, offering a biotechnological route to the biosynthesis of value‐added organofluorines. The fluorinase is k
Externí odkaz:
https://doaj.org/article/30a605b318914efbbf5a7a77aa635e6c
Autor:
Patricia Calero, Daniel C. Volke, Phillip T. Lowe, Charlotte H. Gotfredsen, David O’Hagan, Pablo I. Nikel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Addition of fluorine to organic structures is a unique strategy for tuning molecular properties, but approaches to integrate fluorometabolites into the biochemistry of living cells are scarce. Here, the authors develop a fluoride-responsive genetic c
Externí odkaz:
https://doaj.org/article/1a6013c572344c6f92fbaa1ff47e21f1
Autor:
Phillip T. Lowe, David O’Hagan
Publikováno v:
Chemical Society Reviews. 52:248-276
The history and development of 4'-fluoro-nucleosides is discussed in this review. This is a class of nucleosides which have their origin in the discovery of the rare fluorine containing natural product nucleocidin. Nucleocidin contains a fluorine ato
Autor:
Phillip D. Lowe, J. Richard Carter
Publikováno v:
Castanea. 87
Autor:
Phillip D. Lowe, J. Richard Carter
Publikováno v:
Castanea. 87
Autor:
Emily L. Gillespie, Phillip D. Lowe, J. Richard Carter, Anna Monfils, Travis D. Marsico, Ashley B. Morris, Diana L. Soteropoulos, Ross A. McCauley, Gil Nelson, Erica Krimmel, Michelle J. Smith
Publikováno v:
American Journal of Botany
Premise With digitization and data sharing initiatives underway over the last 15 years, an important need has been prioritizing specimens to digitize. Because duplicate specimens are shared among herbaria in exchange and gift programs, we investigate
Autor:
David O'Hagan, Daniel C. Volke, Charlotte Held Gotfredsen, Patricia Calero, Phillip T. Lowe, Pablo I. Nikel
Publikováno v:
Calero, P, Volke, D C, Lowe, P T, Gotfredsen, C H, O'Hagan, D & Nikel, P I 2020, ' A fluoride-responsive genetic circuit enables in vivo biofluorination in engineered Pseudomonas putida ', Nature Communications, vol. 11, no. 1, 5045 . https://doi.org/10.1038/s41467-020-18813-x
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Fluorine is a key element in the synthesis of molecules broadly used in medicine, agriculture and materials. Addition of fluorine to organic structures represents a unique strategy for tuning molecular properties, yet this atom is rarely found in Nat
Autor:
Konstantinos Markakis, David O'Hagan, Liam Davison-Gates, Alistair Elfick, Susan J. Rosser, Phillip T. Lowe
Publikováno v:
Markakis, K I, Lowe, P T, Davison-gates, L, O’hagan, D, Rosser, S J & Elfick, A 2020, ' An engineered E. coli strain for direct in vivo fluorination ', ChemBioChem . https://doi.org/10.1002/cbic.202000051
ChemBioChem
ChemBioChem
This work was funded by the Industrial Biotechnology Innovation Centre (IBioIC) with support from GlaxoSmithKline, and also the EU Horizon 2020 (Sinfonia consortia). Selectively fluorinated compounds are found frequently in pharmaceutical and agroche
Autor:
Thomas S. Patrick, J. Richard Carter, Wendy B. Zomlefer, Patrick S. Lynch, David E. Giannasi, Jennifer T. Miller, Eric P. Prostko, Steven C. Hughes, Sabrina Y.S. Sewell, James R. Allison, W. Wilson Baker, Alan S. Weakley, Phillip D. Lowe, Ron W. Lance
Publikováno v:
Castanea. 83:124-139
Twenty-seven species, new to the flora of Georgia, are reported here and validated by cited voucher specimens at the University of Georgia (GA) and Valdosta State University (VSC) herbaria, the two largest herbaria in the state. Reassessment and comp
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26339 (2011)
There has been substantial recent change in coral reef communities. To date, most analyses have focussed on static patterns or changes in single variables such as coral cover. However, little is known about how community-level changes occur at large
Externí odkaz:
https://doaj.org/article/c19704722d47440ab1fbf7b925ee1352