Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Phillip A. Laycock"'
Autor:
Kelly Moore, Anthony Li, Niraj Gupta, Tripti Thapa Gupta, Craig Delury, Sean S. Aiken, Phillip A. Laycock, Paul Stoodley
Publikováno v:
Microorganisms, Vol 11, Iss 9, p 2296 (2023)
Background: Multispecies biofilm orthopedic infections are more challenging to treat than mono-species infections. In this in-vitro study, we aimed to determine if a multispecies biofilm, consisting of Gram positive and negative species with differen
Externí odkaz:
https://doaj.org/article/4f38bb01753a4d7ea74eea6f00d85f64
Autor:
Nan Jiang, Devendra H. Dusane, Jacob R. Brooks, Craig P. Delury, Sean S. Aiken, Phillip A. Laycock, Paul Stoodley
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract This study investigated the efficacy of a biphasic synthetic β-tricalcium phosphate/calcium sulfate (β-TCP/CS) bone graft substitute for compatibility with vancomycin (V) in combination with tobramycin (T) or gentamicin (G) evidenced by th
Externí odkaz:
https://doaj.org/article/8ae362f79fc5406b9705b0c0cf9f87d4
Autor:
Kelly Moore, Rebecca Wilson-van Os, Devendra H. Dusane, Jacob R. Brooks, Craig Delury, Sean S. Aiken, Phillip A. Laycock, Anne C. Sullivan, Jeffrey F. Granger, Matthew V. Dipane, Edward J. McPherson, Paul Stoodley
Publikováno v:
Antibiotics, Vol 10, Iss 3, p 270 (2021)
Antibiotic-tolerant bacterial biofilms are notorious in causing PJI. Antibiotic loaded calcium sulfate bead (CSB) bone void fillers and PMMA cement and powdered vancomycin (VP) have been used to achieve high local antibiotic concentrations; however,
Externí odkaz:
https://doaj.org/article/73d731cec21e49d1b7dd880267c830a1
Autor:
Paul Stoodley, Jacob Brooks, Casey W. Peters, Nan Jiang, Craig P. Delury, Phillip A. Laycock, Sean S. Aiken, Devendra H. Dusane
Publikováno v:
Materials, Vol 13, Iss 15, p 3258 (2020)
Carbapenem-resistant Enterobacteriaceae (CRE) and vancomycin-resistant Enterococci (VRE) have emerged as multidrug-resistant (MDR) pathogens associated with periprosthetic joint infections (PJI). In this study, we evaluated the efficacy of antibiotic
Externí odkaz:
https://doaj.org/article/d9e5e2c07caf4b06a4328e54d6bdcace
Autor:
Phillip A. Laycock, John J. Cooper, Robert P. Howlin, Craig Delury, Sean Aiken, Paul Stoodley
Publikováno v:
Materials, Vol 11, Iss 11, p 2265 (2018)
15 different antibiotics were individually mixed with commercially available calcium sulfate bone void filler beads. The antibiotics were: amikacin, ceftriaxone, cefuroxime, ciprofloxacin, clindamycin, colistamethate sodium, daptomycin, gentamicin, i
Externí odkaz:
https://doaj.org/article/84cb9ea341aa459e9c758aba9d1983ab
Autor:
Kelly Moore, Craig Delury, Tripti Thapa Gupta, Devendra H. Dusane, Sean S. Aiken, Paul Stoodley, Matthew V. Dipane, Edward J. McPherson, Anne C. Sullivan, Jacob R. Brooks, Jeffrey F. Granger, Phillip A. Laycock
Publikováno v:
Journal of Bone and Joint Infection. 6:119-129
Introduction: Bacterial biofilms are an important virulence factor in chronic periprosthetic joint infection (PJI) and other orthopedic infection since they are highly tolerant to antibiotics and host immunity. Antibiotics are mixed into carriers suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c0646f346dd9b1b6b2a62890388d82d
https://doi.org/10.5194/jbji-6-119-2021
https://doi.org/10.5194/jbji-6-119-2021
Autor:
Devendra H. Dusane, Craig Delury, Nan Jiang, Jacob R. Brooks, Paul Stoodley, Sean S. Aiken, Phillip A. Laycock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
This study investigated the efficacy of a biphasic synthetic β-tricalcium phosphate/calcium sulfate (β-TCP/CS) bone graft substitute for compatibility with vancomycin (V) in combination with tobramycin (T) or gentamicin (G) evidenced by the duratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfaa9a8e4afd0b50cac36058b8da5549
https://doaj.org/article/8ae362f79fc5406b9705b0c0cf9f87d4
https://doaj.org/article/8ae362f79fc5406b9705b0c0cf9f87d4
Autor:
Jason L. Brown, Mark C. Butcher, Gordon Ramage, Craig Delury, Donald Hansom, Phillip A. Laycock, Rebecca Wilson-van Os
Publikováno v:
Antimicrobial Agents and Chemotherapy
Candida auris provides a substantial global nosocomial threat clinically. With the recent emergence that the organism can readily colonize skin niches, it will likely continue to pose a risk in health care units, particularly to patients undergoing s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8554dc30091d81d5fff2731c8db127
https://pubmed.ncbi.nlm.nih.gov/34694875
https://pubmed.ncbi.nlm.nih.gov/34694875
Autor:
Donald Hansom, Phillip A. Laycock, Jason L. Brown, Craig Delury, Mark C. Butcher, Gordon Ramage, Rebecca Wilson-van Os
Publikováno v:
Antimicrobial Agents and Chemotherapy
Calcium sulfate (CS) has been used clinically as a bone or void filling biomaterial, and due to its resorptive properties have provided the prospect for its use as a release mechanism for local antibiotics to control biofilms. Here, we aimed to test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e185c3ff9262fdf1aa90d65e555ff079
https://doi.org/10.1128/aac.02551-20
https://doi.org/10.1128/aac.02551-20
Autor:
Casey W. Peters, Jacob R. Brooks, Craig Delury, Devendra H. Dusane, Phillip A. Laycock, Sean S. Aiken, Nan Jiang, Paul Stoodley
Publikováno v:
Materials
Volume 13
Issue 15
Materials, Vol 13, Iss 3258, p 3258 (2020)
Volume 13
Issue 15
Materials, Vol 13, Iss 3258, p 3258 (2020)
Carbapenem-resistant Enterobacteriaceae (CRE) and vancomycin-resistant Enterococci (VRE) have emerged as multidrug-resistant (MDR) pathogens associated with periprosthetic joint infections (PJI). In this study, we evaluated the efficacy of antibiotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426e94f134609713b00ab7ebfaddc808