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pro vyhledávání: '"Phillip A. Geter"'
Autor:
Elizabeth Sassani, Beatrix Ueberheide, Linda Clijsters, John F. Dankert, David Fenyö, Michele Pagano, Phillip A. Geter, Keria Bermudez-Hernandez, Gergely Róna, Jeffrey R. Skaar, Robert J. Schneider
Publikováno v:
Molecular Cell. 64:507-519
SLBP (stem-loop binding protein) is a highly conserved factor necessary for the processing, translation, and degradation of H2AFX and canonical histone mRNAs. We identified the F-box protein cyclin F, a substrate recognition subunit of an SCF (Skp1-C
Autor:
Rezina Arju, Abhilash Gadi, Amandine Alard, Sofia Bakogianni, Shah Giashuddin, Phillip A. Geter, Jacqueline Bromberg, Robert J. Schneider, Amanda Ernlund
Publikováno v:
Genesdevelopment. 31(22)
The majority of breast cancers expresses the estrogen receptor (ER+) and is treated with anti-estrogen therapies, particularly tamoxifen in premenopausal women. However, tamoxifen resistance is responsible for a large proportion of breast cancer deat
Autor:
Phillip A. Geter, Robert J. Schneider
Publikováno v:
Cancer Research. 77:B33-B33
Currently, ER+ breast cancer is treated with adjuvant antiestrogen therapies (i.e. tamoxifen and raloxifene). Despite maintaining expression of the estrogen receptor, many women treated with adjuvant therapy develop resistance several years after cur