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pro vyhledávání: '"Phill Monk"'
Autor:
E. Suzanne Cohen, Phill Monk, Alexis C. Cockroft, Ralph Minter, Andrew Buchanan, Lutz Jermutus, Cathy Joberty Candotti, Celia P. Shorrock-Hart, George Thom, David Lowne
Publikováno v:
Proceedings of the National Academy of Sciences. 103:7619-7624
In this study, we used in vitro protein evolution with ribosome and phage display to optimize the affinity of a human IL-13-neutralizing antibody, a therapeutic candidate for the treatment of asthma, >150-fold to 81 pM by using affinity-driven string