Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Philippos A Papathanos"'
Autor:
Aleks Danov, Inbal Pollin, Eric Moon, Mengfei Ho, Brenda A Wilson, Philippos A Papathanos, Tommy Kaplan, Asaf Levy
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 8, Pp 859-879 (2024)
Abstract Secretion systems play a crucial role in microbe-microbe or host-microbe interactions. Among these systems, the extracellular contractile injection system (eCIS) is a unique bacterial and archaeal extracellular secretion system that injects
Externí odkaz:
https://doaj.org/article/32752c8b5d2a490080b6410638854cde
Autor:
Stephanie Gamez, Duverney Chaverra-Rodriguez, Anna Buchman, Nikolay P. Kandul, Stelia C. Mendez-Sanchez, Jared B. Bennett, Héctor M. Sánchez C., Ting Yang, Igor Antoshechkin, Jonny E. Duque, Philippos A. Papathanos, John M. Marshall, Omar S. Akbari
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
CRISPR-based engineering can be used to bias sex ratios. Here the authors develop a transgenic line of Drosophila melanogaster expressing Cas9 from the Y chromosome and functionally characterize the utility of this strain for both sex selection and g
Externí odkaz:
https://doaj.org/article/23f3347c6bb3434c89e6f4fccb8e3b6d
Autor:
Angela Meccariello, Flavia Krsticevic, Rita Colonna, Giuseppe Del Corsano, Barbara Fasulo, Philippos Aris Papathanos, Nikolai Windbichler
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Genetic sex ratio distorters are systems aimed at effecting a bias in the reproductive sex ratio of a population and could be applied for the area-wide control of sexually reproducing insects that vector disease or disrupt agricul
Externí odkaz:
https://doaj.org/article/a75915db982f41418e321ce76f534825
Autor:
Umberto Palatini, Reem A. Masri, Luciano V. Cosme, Sergey Koren, Françoise Thibaud-Nissen, James K. Biedler, Flavia Krsticevic, J. Spencer Johnston, Rebecca Halbach, Jacob E. Crawford, Igor Antoshechkin, Anna-Bella Failloux, Elisa Pischedda, Michele Marconcini, Jay Ghurye, Arang Rhie, Atashi Sharma, Dmitry A. Karagodin, Jeremy Jenrette, Stephanie Gamez, Pascal Miesen, Patrick Masterson, Adalgisa Caccone, Maria V. Sharakhova, Zhijian Tu, Philippos A. Papathanos, Ronald P. Van Rij, Omar S. Akbari, Jeffrey Powell, Adam M. Phillippy, Mariangela Bonizzoni
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-29 (2020)
Abstract Background The Asian tiger mosquito Aedes albopictus is globally expanding and has become the main vector for human arboviruses in Europe. With limited antiviral drugs and vaccines available, vector control is the primary approach to prevent
Externí odkaz:
https://doaj.org/article/1e26c972bac24388a3d71c9152213795
Autor:
Yehonatan Alcalay, Silke Fuchs, Roberto Galizi, Federica Bernardini, Roya Elaine Haghighat-Khah, Douglas B. Rusch, Jeffrey R. Adrion, Matthew W. Hahn, Pablo Tortosa, Rachel Rotenberry, Philippos Aris Papathanos
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Sex-ratio distorters based on X-chromosome shredding are more efficient than sterile male releases for population suppression. X-shredding is a form of sex distortion that skews spermatogenesis of XY males towards the preferential transmission of Y-b
Externí odkaz:
https://doaj.org/article/a6b4faa8d2fc436aa5fb62f07c00713e
Autor:
Barbara Fasulo, Angela Meccariello, Maya Morgan, Carl Borufka, Philippos Aris Papathanos, Nikolai Windbichler
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008647 (2020)
Synthetic sex distorters have recently been developed in the malaria mosquito, relying on endonucleases that target the X-chromosome during spermatogenesis. Although inspired by naturally-occurring traits, it has remained unclear how they function an
Externí odkaz:
https://doaj.org/article/10871200997f4d769d01af1a7638d556
Autor:
Philippos Aris Papathanos, Kostas Bourtzis, Frederic Tripet, Hervé Bossin, Jair Fernandes Virginio, Margareth Lara Capurro, Michelle Cristine Pedrosa, Amadou Guindo, Lakamy Sylla, Mamadou B. Coulibaly, Franck Adama Yao, Patric Stephane Epopa, Abdoulaye Diabate
Publikováno v:
Parasites & Vectors, Vol 11, Iss S2, Pp 165-171 (2018)
Abstract Major efforts are currently underway to develop novel, complementary methods to combat mosquito-borne diseases. Mosquito genetic control strategies (GCSs) have become an increasingly important area of research on account of their species-spe
Externí odkaz:
https://doaj.org/article/ac0abb2a50a94c568b33fe66990e2eff
Autor:
Umberto Palatini, Reem A. Masri, Luciano V. Cosme, Sergey Koren, Françoise Thibaud-Nissen, James K. Biedler, Flavia Krsticevic, J. Spencer Johnston, Rebecca Halbach, Jacob E. Crawford, Igor Antoshechkin, Anna-Bella Failloux, Elisa Pischedda, Michele Marconcini, Jay Ghurye, Arang Rhie, Atashi Sharma, Dmitry A. Karagodin, Jeremy Jenrette, Stephanie Gamez, Pascal Miesen, Patrick Masterson, Adalgisa Caccone, Maria V. Sharakhova, Zhijian Tu, Philippos A. Papathanos, Ronald P. Van Rij, Omar S. Akbari, Jeffrey Powell, Adam M. Phillippy, Mariangela Bonizzoni
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/6a28705a53524a1fac3e63a8f2078c33
Autor:
Alexander Nash, Giulia Mignini Urdaneta, Andrea K. Beaghton, Astrid Hoermann, Philippos Aris Papathanos, George K. Christophides, Nikolai Windbichler
Publikováno v:
Biology Open, Vol 8, Iss 1 (2019)
A first generation of CRISPR-based gene drives has now been tested in the laboratory in a number of organisms, including malaria vector mosquitoes. Challenges for their use in the area-wide genetic control of vector-borne disease have been identified
Externí odkaz:
https://doaj.org/article/a12c7d2743e94064966ae06e8026740b
Autor:
Sophie Tandonnet, Flavia Krsticevic, Tatiana Basika, Philippos A Papathanos, Tatiana T Torres, Maxwell J Scott
Publikováno v:
DNA Research. 30
The New World Screwworm, Cochliomyia hominivorax (Calliphoridae), is the most important myiasis-causing species in America. Screwworm myiasis is a zoonosis that can cause severe lesions in livestock, domesticated and wild animals, and occasionally in