Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Philippe Walker"'
Autor:
Pierre Arsenault, Dan Chiche, William Brown, Jeffrey Miller, Roi Treister, Richard Leff, Philippe Walker, Nathaniel Katz
Publikováno v:
PAIN Reports, Vol 3, Iss 6, p e696 (2018)
Abstract. Introduction:. NEO6860 is a TRPV1 antagonist when activated by capsaicin but not by heat or pH, developed to relieve pain without the adverse events reported with non–modality-selective TRPV1 antagonists. Objective:. The primary Objective
Externí odkaz:
https://doaj.org/article/76286f4ee80b494f83f00c2c695f8d0a
Autor:
Jean-Daniel Lalau, Philippe Walker
Publikováno v:
Médecine des Maladies Métaboliques. 16:444-449
Quelle démarche méthodologique afin d’aboutir à une offre pertinente de soins palliatifs à Mayotte ?
Publikováno v:
Santé Publique. 33:185-190
Objectif : Le departement de Mayotte presente un retard important dans l’acces aux soins palliatifs. Nous presentons la demarche methodologique d’evaluation des besoins en soins palliatifs de la population ayant conduit a faire une proposition d
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 19; Issue 6; Pages: 3540
Background/Aim: Mayotte is a French island in the Indian Ocean. There is no palliative care structure in this territory. The island and its population have specific characteristics: insularity, poverty, coexistence of modern and traditional medicine,
Autor:
Andrew Griffin, Stuart Hossack, Richard L. Leff, Dan A. Chiche, Philippe Walker, Roxane Aubray, William Brown
Publikováno v:
The Journal of Pain. 18:726-738
Most previous transient receptor potential vanilloid subtype 1 (TRPV1) antagonist programs have been put on hold, mainly because of on-target adverse events: hyperthermia and impaired noxious heat sensation. NEO6860 is a TRPV1 antagonist, blocking ca
Autor:
Richard L. Leff, Jeffrey Miller, Philippe Walker, Pierre Arsenault, Roi Treister, Nathaniel P. Katz, William Brown, Dan A. Chiche
Publikováno v:
Pain Reports
PAIN Reports, Vol 3, Iss 6, p e696 (2018)
PAIN Reports, Vol 3, Iss 6, p e696 (2018)
Introduction:. NEO6860 is a TRPV1 antagonist when activated by capsaicin but not by heat or pH, developed to relieve pain without the adverse events reported with non–modality-selective TRPV1 antagonists. Objective:. The primary Objective of this s
Autor:
Hans R. Brunner, Eric Grouzmann, Philippe Walker, Michel Burnier, Gabriel Centeno, Bernard Waeber
These experiments were designed to assess the ability of the new nonpeptide angiotensin II antagonist DuP 753 to inhibit the binding and, particularly, to antagonize the cellular response to angiotensin II in human platelets and primary cultures of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6bd7282aca337947b4e9ec373ce2bac
http://doc.rero.ch/record/298619/files/4-5_Pt_1-438.pdf
http://doc.rero.ch/record/298619/files/4-5_Pt_1-438.pdf
Autor:
Katia Befort, Fabien Decaillot, Brigitte L. Kieffer, Philippe Walker, ShiYi Yue, Dominique Filliol
Publikováno v:
Nature Structural & Molecular Biology. 10:629-636
The high resolution structure of rhodopsin has greatly enhanced current understanding of G protein-coupled receptor (GPCR) structure in the off-state, but the activation process remains to be clarified. We investigated molecular mechanisms of delta-o
Autor:
S. H. Shen, Dajan O'Donnell, Daniel Menard, Kem Payza, William Brown, Claes Wahlestedt, Sultan Ahmad, Philippe Walker, Ralf Schmidt, Julie Ducharme
Publikováno v:
Annals of the New York Academy of Sciences. 863:108-119
We have identified a novel subtype of galanin receptor (GALR-2) in rat dorsal root ganglia and spinal cord. The open reading frame of GALR-2 is 1116 nucleotides long, encoding a protein of 372 amino acids with a theoretical molecular mass of 40.7 kD.
Publikováno v:
Journal of Biological Chemistry. 272:9260-9267
A novel "restoration of function" mutagenesis strategy was developed to identify amino acid sequence combinations necessary to restore the ability to bind delta-selective ligands to an inactive delta/mu receptor chimera in which 10 amino acids of the