Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Philippe Viallefont"'
Publikováno v:
Tetrahedron: Asymmetry. 13:503-510
The diastereoselective synthesis of α-amino acids by radical addition to dehydroalanine derivatives of pantolactone using the stannane method both in the presence and absence of Lewis acid catalysts is reported. The absolute configuration of the new
Publikováno v:
Synthetic Communications. 32:181-187
Reaction of urethane N-carboxyanhydrides with unprotected amino sugars was the key step in the synthesis of new trimodular surfactants.
Synthèse et réactivité des dérivés de la 2,3-dihydro-3-hydroxy-2-phényl-1,5-benzothiazépin-4(5H)-one
Autor:
El Mokhtar Essassi, Hamza El Meslouhi, Moussa Salem, Abdelfettah Zerzouf, Philippe Viallefont, Marie-Louise Roumestant
Publikováno v:
Comptes Rendus de l'Académie des Sciences - Series IIC - Chemistry. 4:925-931
New 1,5-benzothiazepinone derivatives have been synthesized. The cycloaddition of benzylazide with 5-propargyl-1,5-benzothiazepinone 7 gave compounds 9 and 10 . The 1,5-benzothiazepinone 8 reacts with hydrazine to give 1,5-benzothiazepinone 11, which
Autor:
L. Lecointe, M. L. Roumestant, Valérie Rolland, Philippe Viallefont, J. Martine, L. Pappalardo
Publikováno v:
The Journal of Peptide Research. 55:300-307
The synthesis of enantiomerically pure azatyrosine, tribromophenylalanine and trichlorophenylalanine is described, using two methods, diastereoselective alkylation and (or) diastereoselective protonation of chiral enolates.
Autor:
Moussa Salem, El Mokhtar Essassi, Marie-Louise Roumestant, Abdelfettah Zerzouf, Philippe Viallefont, Abdoulay Keita
Publikováno v:
Comptes Rendus de l'Académie des Sciences - Series IIC - Chemistry. 2:435-439
Resume Le 2-(4-methylphenyl)acyl-l,3-benzothiazole 3b reagit avec le N -bromosuccinimide pour donner le produit de dimerisation 4 . Ce dernier, porte au refux du triethylphosphite, se transforme en furane 5. Le 2-phenacyl-1,3-benzothiazole 3a , apres
Publikováno v:
Tetrahedron Letters. 40:4535-4538
The first synthesis of N-acetyl-α-amino acids by radical addition on solid support to commercialy available 2-acetamidoacrylic acid using the mercury method is described The reaction proceeds in acceptable chemical efficiency (49–60'9) depending o
Autor:
Jean-Marie Receveur, M. L. Roumestant, Philippe Viallefont, Janique Guiramand, Jean Martinez, Max Récasens
Publikováno v:
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 1998, 8 (2), pp.127-32. ⟨10.1016/S0960-894X(97)10208-6⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 1998, 8 (2), pp.127-32. ⟨10.1016/S0960-894X(97)10208-6⟩
International audience; In order to develop new specific glutamate analogues at metabotropic glutamate receptors, Diels-Alder, 1-4 ionic and radical reactions were performed starting from (2S)-4-methyleneglutamic acid. Preliminary pharmacological eva
Publikováno v:
Tetrahedron: Asymmetry. 8:949-955
Asymmetric synthesis of various glycosyl-α-aminoacids is described. The approach involves the diastereoselective condensation of glycine enolates on the carbonyl in position 3 of the suitably protected α-D-ribohexofuranos-3-ulose.
Publikováno v:
Tetrahedron Letters. 38:1563-1566
Functionalised diketopiperazines (DKPs) are easily obtained optically pure by disymmetrization of a mesopyrrolidine and can be easily converted to an α-amino amine containing compound. As a first example, one of the new chiral auxiliaries has been u
Publikováno v:
Catalysis Letters. 27:235-240
Esterification and transesterification reactions are carried out in water miscible organic solvents by using a new glutamic acid specific endopeptidase, isolated from Bacillus lichenifonnis. Sweetener aspartam analogues syntheses are also described.