Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Philippe Sucosky"'
Autor:
Philippe Sucosky, Varun Vinayak Kalaiarasan, Graham B. Quasebarth, Patricia Strack, Jason A. Shar
Publikováno v:
npj Microgravity, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Long-duration spaceflight poses multiple hazards to human health, including physiological changes associated with microgravity. The hemodynamic adaptations occurring upon entry into weightlessness have been associated with retrograde stagnan
Externí odkaz:
https://doaj.org/article/0093137268c34b02a75d9469a3112474
Autor:
Aditya K. Birla, Sunita Brimmer, Walker D. Short, Oluyinka O. Olutoye, Jason A. Shar, Suriya Lalwani, Philippe Sucosky, Anitha Parthiban, Sundeep G. Keswani, Christopher A. Caldarone, Ravi K. Birla
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Hypoplastic left heart syndrome (HLHS) is a complex congenital heart condition in which a neonate is born with an underdeveloped left ventricle and associated structures. Without palliative interventions, HLHS is fatal. Treatment typically includes m
Externí odkaz:
https://doaj.org/article/1892a1c201dc41208ade5c3bde0ebd55
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Discrete subaortic stenosis (DSS) is an obstruction of the left ventricular outflow tract (LVOT) due to the formation of a fibromuscular membrane upstream of the aortic valve. DSS is a major risk factor for aortic regurgitation (AR), which often pers
Externí odkaz:
https://doaj.org/article/584871d1212d4b5db4d84819b4f33824
Autor:
Danielle D. Massé, Jason A. Shar, Kathleen N. Brown, Sundeep G. Keswani, K. Jane Grande-Allen, Philippe Sucosky
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Discrete subaortic stenosis (DSS) is a congenital heart disease that results in the formation of a fibro-membranous tissue, causing an increased pressure gradient in the left ventricular outflow tract (LVOT). While surgical resection of the membrane
Externí odkaz:
https://doaj.org/article/ec8a1d5a40d746aba5d89bba96dcf01c
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The bicuspid aortic valve (BAV) generates wall shear stress (WSS) abnormalities in the ascending aorta (AA) that may be responsible for the high prevalence of aortopathy in BAV patients. While previous studies have analyzed the magnitude and oscillat
Externí odkaz:
https://doaj.org/article/6055404289924800904832f5b49a3453
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84433 (2013)
Calcific aortic valve disease (CAVD) is an active process presumably triggered by interplays between cardiovascular risk factors, molecular signaling networks and hemodynamic cues. While earlier studies demonstrated that alterations in fluid shear st
Externí odkaz:
https://doaj.org/article/d8f4d80422524ca2a4eced3c6f4c678a
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48843 (2012)
The bicuspid aortic valve (BAV) is the most common congenital cardiac anomaly and is frequently associated with calcific aortic valve disease (CAVD). The most prevalent type-I morphology, which results from left-/right-coronary cusp fusion, generates
Externí odkaz:
https://doaj.org/article/4b2787c2793f4a02a1b3fea673ca2289
Publikováno v:
International Journal of Inflammation, Vol 2011 (2011)
Cardiac valves function in a mechanically complex environment, opening and closing close to a billion times during the average human lifetime, experiencing transvalvular pressures and pulsatile and oscillatory shear stresses, as well as bending and a
Externí odkaz:
https://doaj.org/article/b30549b1b316478b92a41bee3cfb3a16
Autor:
Kathleen N. Brown, Hong Kim T. Phan, Tasneem Mustafa, Jennifer P. Connell, Philippe Sucosky, Sundeep G. Keswani, K. Jane Grande-Allen
Discrete subaortic stenosis (DSS) is a congenital heart disease characterized by the formation of a fibrotic membrane below the aortic valve. The underlying cellular mechanisms of this disease are currently unknown. As one of the distinguishing featu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b437218d49de70f1cda87365e5aef30
https://doi.org/10.1101/2022.12.05.519049
https://doi.org/10.1101/2022.12.05.519049
Publikováno v:
Cardiovasc Eng Technol
PURPOSE. Discrete subaortic stenosis (DSS) is a left-ventricular outflow tract (LVOT) obstruction caused by a membranous lesion. DSS is associated with steep aortoseptal angles (AoSAs) and is a risk factor for aortic regurgitation (AR). However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccfbf4b0d558edd506e8dc9da2af872
https://doi.org/10.1007/s13239-020-00513-8
https://doi.org/10.1007/s13239-020-00513-8