Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Philippe Poindron"'
Autor:
Alexandre Henriques, Laura Rouvière, Elodie Giorla, Clémence Farrugia, Bilal El Waly, Philippe Poindron, Noëlle Callizot
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9864 (2022)
Mitochondria, α-syn fibrils and the endo-lysosomal system are key players in the pathophysiology of Parkinson’s disease. The toxicity of α-syn is amplified by cell-to-cell transmission and aggregation of endogenous species in newly invaded neuron
Externí odkaz:
https://doaj.org/article/9083dbe6c34e4f1b9a4e0efa9b0b2d2d
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215277 (2019)
Most of the Parkinson's disease (PD) cases are sporadic, although several genes are directly related to PD. Several pathways are central in PD pathogenesis: protein aggregation linked to proteasomal impairments, mitochondrial dysfunctions and impairm
Externí odkaz:
https://doaj.org/article/7744094ecd4f41b3a88ec47efce16a38
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 4, Pp 626-635 (2001)
Sensory neuropathies are frequently associated with diabetes or with antimitotic treatments in humans suffering from cancer, and are in this case the most important limitation to the use of antimitotic drugs. For this reason, there is a need to estab
Externí odkaz:
https://doaj.org/article/2e839d93a05a454881268208240c9bca
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 3, Pp 447-458 (2001)
The frissonnant (fri) mutation is an autosomic recessive mutation which spontaneously appeared in the stock of C3H mice. fri mutant mice have locomotor instability and rapid tremor. Since tremor ceases when mutant mice have sleep or are anaesthetized
Externí odkaz:
https://doaj.org/article/fb8494878ed04c85a8646ae98fdd2124
Autor:
Philippe F. Kennel, Paul Fonteneau, Elisabeth Martin, Jean-Marc Schmidt, Mimoun Azzouz, Jacques Borg, Jean-Louis Guenet, Henning Schmalbruch, Jean-Marie Warter, Philippe Poindron
Publikováno v:
Neurobiology of Disease, Vol 3, Iss 2, Pp 137-147 (1996)
The mouse autosomal recessive mutation progressive motor neuronopathy (pmn) results in early onset motor neuron disease with rapidly progressive hindlimb paralysis, severe muscular wasting, and death at around 6 weeks of age. This mutant provides opp
Externí odkaz:
https://doaj.org/article/e479a197653d4eb091b69aa009a1136f
Autor:
Noelle Callizot, Alexandre Henriques, Laura Rouviere, Elodie Giorla, Bilal El Waly, Philippe Poindron
Publikováno v:
Alzheimer's & Dementia. 18
Publikováno v:
Alzheimer's & Dementia. 16
Publikováno v:
Journal of Neuroscience Research. 93:633-643
Murine models of Alzheimer's disease with elevated levels of amyloid-β (Aβ) peptide present motor axon defects and neuronal death. Aβ1-42 accumulation is observed in motor neurons and spinal cords of sporadic and familial cases of amyotrophic late
Publikováno v:
Alzheimer's & Dementia. 13
Publikováno v:
Alzheimer's & Dementia. 15:P1335-P1335