Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Philippe Pierre Robichaud"'
Publikováno v:
Bulletin of the National Research Centre, Vol 47, Iss 1, Pp 1-10 (2023)
Abstract Background The protein phosphatase 2 (PP2A) is one of the major serine/threonine phosphatases in humans. The most frequently reported pathogenic PP2A variants have been identified in PPP2R5D, encoding the regulatory subunit B’ delta, and a
Externí odkaz:
https://doaj.org/article/355f5540c12b47669aec37baa2f16ac2
Autor:
Philippe Pierre Robichaud, Eric P. Allain, Sarah Belbraouet, Claude Bhérer, Jean Mamelona, Jason Harquail, Stéphanie Crapoulet, Nicolas Crapoulet, Mathieu Bélanger, Mouna Ben Amor
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Background Founder populations that have recently undergone important genetic bottlenecks such as French-Canadians and Ashkenazi Jews can harbor some pathogenic variants at a higher carrier rate than the general population, putting them at a
Externí odkaz:
https://doaj.org/article/d3ae837d67ef4302a689bd21bc68ae3f
Autor:
Charles E. Bullerwell, Philippe Pierre Robichaud, Pierre M. L. Deprez, Andrew P. Joy, Gabriel Wajnberg, Darwin D’Souza, Simi Chacko, Sébastien Fournier, Nicolas Crapoulet, David A. Barnett, Stephen M. Lewis, Rodney J. Ouellette
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract PAX5 and EBF1 work synergistically to regulate genes that are involved in B lymphocyte differentiation. We used the KIS-1 diffuse large B cell lymphoma cell line, which is reported to have elevated levels of PAX5 expression, to investigate t
Externí odkaz:
https://doaj.org/article/5b11cbd215904b91952bccb6c01327a7
Autor:
Philippe Pierre Robichaud, Samuel J. Poirier, Luc H. Boudreau, Jérémie A. Doiron, David A. Barnett, Eric Boilard, Marc E. Surette
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 10, Pp 1821-1830 (2016)
Alkyne and azide analogs of natural compounds that can be coupled to sensitive tags by click chemistry are powerful tools to study biological processes. Arachidonic acid (AA) is a FA precursor to biologically active compounds. 19-Alkyne-AA (AA-alk) i
Externí odkaz:
https://doaj.org/article/96f465ded1894cbf96aeac01ccc35d14
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 10, Pp 2665-2677 (2013)
Changes in fatty acid (FA) and glycerophospholipid (GPL) metabolism associated with cell cycle entry are not fully understood. In this study FA-GPL remodeling was investigated in resting and proliferating primary human T cells. Significant changes we
Externí odkaz:
https://doaj.org/article/f82bc457d0684255bbbd0797bad8a185
Publikováno v:
Biochemical and biophysical research communications. 607
When performing western blots for protein detection using the classical Laemmli method, experimenters often encounter difficulties with the detection of transmembrane proteins involved in lipid or fatty acid metabolism. A crucial phase in sample prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24013de5b87aacc3f96294053d545e60
https://pubmed.ncbi.nlm.nih.gov/35367822
https://pubmed.ncbi.nlm.nih.gov/35367822
Autor:
Michel Laviolette, Marie-Chantal Larose, Anne-Sophie Archambault, Cyril Martin, Caroline Turcotte, Samuel J. Poirier, Julie-S Lefebvre, Véronique Provost, Philippe-Pierre Robichaud, Nicolas Flamand, Patrick P. McDonald, Luc H. Boudreau, Marc E. Surette
Publikováno v:
Journal of Leukocyte Biology. 105:1131-1142
Leukotriene B4 (LTB4) plays a prominent role in innate immunity as it induces phagocyte recruitment, the release of antimicrobial effectors, and as it potentiates the ingestion and killing of pathogens. In humans, LTB4 has a short half-life and is ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aed4cf994c9f30678c892657943cf23
https://doi.org/10.1002/jlb.ma0718-306r
https://doi.org/10.1002/jlb.ma0718-306r
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2383-2396 (2018)
Journal of Lipid Research
Journal of Lipid Research
PUFAs are important constituents of membrane glycerophospholipids. However, changes in the capacities to incorporate and metabolize PUFAs when cells enter the cell cycle have not been thoroughly studied. In this study, differences in the incorporatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54bcdc459ef7347822416948c8729a6
https://doi.org/10.1194/jlr.m090050
https://doi.org/10.1194/jlr.m090050
Autor:
Andrew P. Joy, Rodney J. Ouellette, David Barnett, Charles E. Bullerwell, Philippe Pierre Robichaud, Pierre M. L. Deprez, Gabriel Wajnberg, Darwin D’Souza, Simi Chacko, Stephen M. Lewis, Stéphanie Fournier, Nicolas Crapoulet
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
PAX5 and EBF1 work synergistically to regulate genes that are involved in B lymphocyte differentiation. We used the KIS-1 diffuse large B cell lymphoma cell line, which is reported to have elevated levels of PAX5 expression, to investigate the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e325414fdc3a58bc7f782e3fce9203
https://doi.org/10.1038/s41598-021-81000-5
https://doi.org/10.1038/s41598-021-81000-5
Autor:
Pier Jr Morin, Philippe-Pierre Robichaud, Colleen O’Connell, Rodney J. Ouellette, Michael Arseneault
Publikováno v:
Neuroscience Letters. 750:135813
DNA methylation has garnered much attention in recent years for its diagnostic potential in multiple conditions including cancer and neurodegenerative diseases. Conversely, advances regarding the potential diagnostic relevance of DNA methylation stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee085325efdd7be9e85b50caaa8f5888
https://doi.org/10.1016/j.neulet.2021.135813
https://doi.org/10.1016/j.neulet.2021.135813