Radiolysis of myoglobin concentrated gels by protons: specific changes in secondary structure and production of carbon monoxide

Autor: Nicolas Ludwig, Catherine Galindo, Clea Witjaksono, Antoine Danvin, Philippe Peaupardin, Dominique Muller, Tamon Kusumoto, Satoshi Kodaira, Rémi Barillon, Quentin Raffy

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Abstract While particle therapy has been used for decades for cancer treatment, there is still a lack of information on the molecular mechanisms of biomolecules radiolysis by accelerated ions. Here, we examine the effects of accelerated protons on hi

Externí odkaz: https://doaj.org/article/f17830e876b14834ac63710da35280bc

Quantitative estimation of track segment yields of water radiolysis species under heavy ions around Bragg peak energies using Geant4-DNA

Autor: Nicolas Ludwig, Masayori Ishikawa, Philippe Peaupardin, Shogo Okada, Quentin Raffy, Ryo Ogawara, Kentaro Baba, Tamon Kusumoto, Satoshi Kodaira, Catherine Galindo, Rémi Barillon

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.1524. ⟨10.1038/s41598-021-81215-6⟩

International audience; AbstractWe evaluate the track segment yield G′ of typical water radiolysis products (eaq−, ·OH and H2O2) under heavy ions (He, C and Fe ions) using a Monte Carlo simulation code in the Geant4-DNA. Furthermore, we reproduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad34c3f8bad793ac5c8553527ce3c23