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pro vyhledávání: '"Philippe Milot-Rousseau"'
Autor:
Claudia Goupil, Robert A. Whittington, Pershia Samadi, Emmanuel Planel, Francesca Cicchetti, Stéphanie Bissonnette, Giulia Cisbani, Sébastien S. Hébert, Maud Gratuze, Philippe Milot-Rousseau, Carl Julien, Isabelle Poitras, Françoise Morin, J. Alex Parker, Anastasia Noël, François Bezeau, Maya Dickler
Publikováno v:
Human molecular genetics. 24(1)
Huntington's disease (HD) is an autosomal-dominant neurodegenerative disorder caused by polyglutamine expansions in the amino-terminal region of the huntingtin (Htt) protein. At the cellular level, neuronal death is accompanied by the proteolytic cle