Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Philippe Metz"'
Autor:
Marion Poenisch, Philippe Metz, Hagen Blankenburg, Alessia Ruggieri, Ji-Young Lee, Daniel Rupp, Ilka Rebhan, Kathrin Diederich, Lars Kaderali, Francisco S Domingues, Mario Albrecht, Volker Lohmann, Holger Erfle, Ralf Bartenschlager
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004573 (2015)
Hepatitis C virus (HCV) is a major cause of chronic liver disease affecting around 130 million people worldwide. While great progress has been made to define the principle steps of the viral life cycle, detailed knowledge how HCV interacts with its h
Externí odkaz:
https://doaj.org/article/bfca700823ac4c7ba33e74991835f062
Autor:
Peter Schemmer, Ralf Bartenschlager, Georgios Polychronidis, A Restuccia, Katrin Hoffmann, Benjamin Schusser, Ronald Koschny, K Schöneweis, Philippe Metz, Florian A. Lempp, Stephan Urban, Pascal Mutz, Jamie Frankish, Thomas F. Baumert, Silke Bender, Marco Binder, Stefan Seitz, Thomas Tu, Bingqian Qu
Publikováno v:
Zeitschrift für Gastroenterologie. 56:E2-E89
Autor:
Agnese Restuccia, Peter Schemmer, Ralf Bartenschlager, Silke Bender, Stefan Seitz, Katrin Schöneweis, Florian A. Lempp, Pascal Mutz, Ronald Koschny, Thomas Tu, Jamie Frankish, Thomas F. Baumert, Bingqian Qu, Marco Binder, Stephan Urban, Katrin Hoffmann, Christopher Dächert, Philippe Metz, Benjamin Schusser, Georgios Polychronidis
Publikováno v:
Gastroenterology
Gastroenterology, 2018, 154 (6), pp.1791-1804. ⟨10.1053/j.gastro.2018.01.044⟩
Gastroenterology, 2018, 154 (6), pp.1791-1804. ⟨10.1053/j.gastro.2018.01.044⟩
Background & Aims Hepatitis C virus (HCV) infection is sensitive to interferon (IFN)-based therapy, whereas hepatitis B virus (HBV) infection is not. It is unclear whether HBV escapes detection by the IFN-mediated immune response or actively suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c88fea075a678a20fe2c4922271212c
https://hal.archives-ouvertes.fr/hal-02441618
https://hal.archives-ouvertes.fr/hal-02441618
Publikováno v:
ResearcherID
SummaryInfections with the hepatitis C virus (HCV) are a major cause of chronic liver disease. While the acute phase of infection is mostly asymptomatic, this virus has the high propensity to establish persistence and in the course of one to several
Autor:
Marc P. Windisch, Volker Lohmann, Ralf Bartenschlager, Artur Kaul, Johanna Mazur, Lars Kaderali, Philippe Metz, Alessia Ruggieri, Michael Frese, Marco Binder, Martin Trippler, Ulf Zeuge, Eva Dazert
Publikováno v:
Hepatology. 56:2082-2093
Persistent infection with hepatitis C virus (HCV) can lead to chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. All current therapies of hepatitis C include interferon-alpha (IFN-α). Moreover, IFN-gamma (IFN-γ), the only type II IFN
Autor:
Mario Albrecht, Alessia Ruggieri, Philippe Metz, Ilka Rebhan, Volker Lohmann, Francisco S. Domingues, Daniel Rupp, Ralf Bartenschlager, Lars Kaderali, Kathrin Diederich, Holger Erfle, Ji-Young Lee, Marion Poenisch, Hagen Blankenburg
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004573 (2015)
PLoS Pathogens
PLoS Pathogens
Hepatitis C virus (HCV) is a major cause of chronic liver disease affecting around 130 million people worldwide. While great progress has been made to define the principle steps of the viral life cycle, detailed knowledge how HCV interacts with its h
Autor:
Michael Frese, Volker Lohmann, Marc P. Windisch, Oliver Grünvogel, Oliver T. Fackler, Anna Reustle, Alessia Ruggieri, Martin Trippler, Ralf Bartenschlager, Philippe Metz, Marco Binder, Philipp Schult, Birthe Müller, Katharina Esser-Nobis
All major types of interferon (IFN) efficiently inhibit hepatitis C virus (HCV) replication in vitro and in vivo . Remarkably, HCV replication is not sensitive to IFN-γ in the hepatoma cell line Huh6, despite an intact signaling pathway. We performe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9989d34fb38c56b79653cd3b05000abb
https://www.ncbi.nlm.nih.gov/pubmed/26269178
https://www.ncbi.nlm.nih.gov/pubmed/26269178
Autor:
Anne Hamacher-Brady, Nathan R. Brady, Abhilash I. Chiramel, Rodrigo Mora-Rodriguez, Philippe Metz, Gang Long, Ralf Bartenschlager, Laurent Chatel-Chaix, Peter Bankhead, Gualtiero Alvisi
Autophagic flux involves formation of autophagosomes and their degradation by lysosomes. Autophagy can either promote or restrict viral replication. In the case of Dengue virus (DENV), several studies report that autophagy supports the viral replicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c37a6fdc769f8782e8050ca47ce10d3
http://hdl.handle.net/11577/3158061
http://hdl.handle.net/11577/3158061
Publikováno v:
Sensors and Actuators A: Physical. :1-11
Emerging conducting polymer electromechanical actuators (CPEA) have many potential applications ranging from biomedical to micro/nano manipulation systems. In order to make use of their potential, it is needed to establish a valid mathematical model
Publikováno v:
Smart Materials and Structures. 15:243-252
This paper focuses on a geometry optimization methodology based on a lumped-parameter mathematical model, which accepts the voltage as the input, and bending angle and bending moment as the outputs, for a trilayer bending-type polymer actuator. An an