The Absence of Pupylation (Prokaryotic Ubiquitin-Like Protein Modification) Affects Morphological and Physiological Differentiation in Streptomyces coelicolor

Autor: Hasna Boubakri, Oldřich Benada, Nicolas Seghezzi, Philippe Mazodier, Magalie Duchateau, Jean-Luc Pernodet, Olga Kofroňová, Myriam Gominet

Publikováno v: Journal of Bacteriology
Journal of Bacteriology, 2015, 197 (21), pp.3388-99. ⟨10.1128/JB.00591-15⟩
Journal of Bacteriology, American Society for Microbiology, 2015, 197 (21), pp.3388-99. 〈10.1128/JB.00591-15〉
Journal of Bacteriology, American Society for Microbiology, 2015, 197 (21), pp.3388-99. ⟨10.1128/JB.00591-15⟩

Protein turnover is essential in all living organisms for the maintenance of normal cell physiology. In eukaryotes, most cellular protein turnover involves the ubiquitin-proteasome pathway, in which proteins tagged with ubiquitin are targeted to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a34057edcbcf74e38ae5f382889616e
https://hal.science/hal-01430740

The lon gene, encoding an ATP-dependent protease, is a novel member of the HAIR/HspR stress-response regulon in actinomycetes

Autor: Philippe Mazodier, Julie Viala, André Sobczyk, Audrey Bellier

Publikováno v: Microbiology
Microbiology, 2002, 148 (6), pp.1931-1937. ⟨10.1099/00221287-148-6-1931⟩
Microbiology, Microbiology Society, 2002, 148 (6), pp.1931-1937. ⟨10.1099/00221287-148-6-1931⟩

International audience; Members of a family of ATP-dependent proteases related to Lon from Escherichia coli are present in most prokaryotes and eukaryotes. These proteases are generally reported to be heat induced, and various regulatory systems have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca487b3c1405df3253cfa66e89402bcf
https://doi.org/10.1099/00221287-148-6-1931

Identified members of the Streptomyces lividans AdpA regulon involved in differentiation and secondary metabolism

Autor: Nadia Benaroudj, Philippe Mazodier, Caroline Proux, Aurelie Guyet, Jean-Yves Coppée, Myriam Gominet

Publikováno v: BMC Microbiology
BMC Microbiology, BioMed Central, 2014, 14 (1), pp.81. ⟨10.1186/1471-2180-14-81⟩
BMC Microbiology, 2014, 14 (1), pp.81. ⟨10.1186/1471-2180-14-81⟩

International audience; BACKGROUND: AdpA is a key transcriptional regulator involved in the complex growth cycle of Streptomyces. Streptomyces are Gram-positive bacteria well-known for their production of secondary metabolites and antibiotics. Most w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67916fbec9f3326dbcafa19559358485
https://hal-pasteur.archives-ouvertes.fr/pasteur-00979918

The clpP multigenic family in Streptomyces lividans: conditional expression of the clpP3 clpP4 operon is controlled by PopR, a novel transcriptional activator

Autor: Georges Rapoport, Philippe Mazodier, Julie Viala

Publikováno v: Molecular Microbiology
Molecular Microbiology, Wiley, 2000, 38 (3), pp.602-612. ⟨10.1046/j.1365-2958.2000.02155.x⟩
Molecular Microbiology, 2000, 38 (3), pp.602-612. ⟨10.1046/j.1365-2958.2000.02155.x⟩

International audience; The clpP genes are widespread among living organisms and encode the proteolytic subunit of the Clp ATP-dependent protease. These genes are present in a single copy in most eubacteria. However, five clpP genes were identified i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a759b016706af9512d386e99cfee1a
https://doi.org/10.1046/j.1365-2958.2000.02155.x

Alteration of the synthesis of the Clp ATP-dependent protease affects morphological and physiological differentiation in Streptomyces

Autor: Philippe Mazodier, Pascale Servant‐Moisson, Cosette Grandvalet, Valérie de Crécy-Lagard, Julie Viala

Publikováno v: Molecular Microbiology
Molecular Microbiology, Wiley, 1999, 32 (3), pp.505-517. ⟨10.1046/j.1365-2958.1999.01364.x⟩
Molecular Microbiology, 1999, 32 (3), pp.505-517. ⟨10.1046/j.1365-2958.1999.01364.x⟩

International audience; The genes of Streptomyces coelicolor A3(2) encoding catalytic subunits (ClpP) and regulatory subunits (ClpX and ClpC) of the ATP-dependent protease family Clp were cloned, mapped and characterized. S. coelicolor contains at le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c397c708cb8588b8deb1d71288f0ce
https://doi.org/10.1046/j.1365-2958.1999.01364.x