Cord blood-endothelial colony forming cells are immunotolerated and participate at post-ischemic angiogenesis in an original dorsal chamber immunocompetent mouse model

Autor: Richard Proust, Anne-Charlotte Ponsen, Valérie Rouffiac, Chantal Schenowitz, Florent Montespan, Karine Ser-Le Roux, Frédéric De Leeuw, Corinne Laplace-Builhé, Philippe Mauduit, Edgardo D. Carosella, Sébastien Banzet, Jean-Jacques Lataillade, Nathalie Rouas-Freiss, Georges Uzan, Juliette Peltzer

Publikováno v: Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-13 (2020)

Abstract Background Cardiovascular diseases are the main cause of morbidity and mortality worldwide. Restoring blood supply to ischemic tissues is an essential goal for the successful treatment of these diseases. Growth factor or gene therapy efficac

Externí odkaz: https://doaj.org/article/0194969ff25544469d73275cc587a140

Interferon-γ and Hypoxia Priming Have Limited Effect on the miRNA Landscape of Human Mesenchymal Stromal Cells-Derived Extracellular Vesicles

Autor: Juliette Peltzer, Kyle Lund, Marie-Emmanuelle Goriot, Marion Grosbot, Jean-Jacques Lataillade, Philippe Mauduit, Sébastien Banzet

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

Mesenchymal stromal cell (MSC)-based cell therapy has received great interest in regenerative medicine. Priming the cells during the culture phase can improve their efficacy and/or survival after injection. The literature suggests that MSC extracellu

Externí odkaz: https://doaj.org/article/b939ebb5545a48249e175606d308edec

An Evaluation of Different Types of Peptone as Partial Substitutes for Animal-derived Serum in Vero Cell Culture

Autor: Chloe Lezin, Philippe Mauduit, Georges Uzan, Mohamed Essameldin Abdelgawad

Publikováno v: Alternatives to Laboratory Animals. 50:339-348

Vero cells are one of the most frequently used cell types in virology. They can be used not only as a vehicle for the replication of viruses, but also as a model for investigating viral infectivity, cytopathology and vaccine production. There is incr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea5f9e367f298cd39d20e538a8bca8c
https://doi.org/10.1177/02611929221122780

Abstract 3665: Umbilical cord blood endothelial progenitor cell-derived extracellular vesicles control important endothelial cell functions

Autor: Sawssen Ben Fraj, Sina Naserian, Bileyle Lorenzini, Sylvie Goulinet, Philippe Mauduit, Georges Uzan, Houda Haouas

Publikováno v: Cancer Research. 83:3665-3665

Background: Circulating endothelial progenitor cells (EPCs) play a pivotal role in vascular regeneration and the repair of diseases in which angiogenesis is required, including ischemia and tissue transplantation. Although they are a potentially valu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cbf8ce1f4487d4876120424f0b559ee5
https://doi.org/10.1158/1538-7445.am2023-3665

TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals

Autor: Emmanuel Dornier, Franck Coumailleau, Jean-François Ottavi, Julien Moretti, Claude Boucheix, Philippe Mauduit, François Schweisguth, Eric Rubinstein

Publikováno v: Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2012, 199 (3), pp.481-496. ⟨10.1083/jcb.201201133⟩
Journal of Cell Biology, 2012, 199 (3), pp.481-496. ⟨10.1083/jcb.201201133⟩

International audience; The metalloprotease ADAM10/Kuzbanian catalyzes the ligand-dependent ectodomain shedding of Notch receptors and activates Notch. Here, we show that the human tetraspanins of the evolutionary conserved TspanC8 subfamily (Tspan5,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e20352bf39f67c5156bc01cad2e366
https://doi.org/10.1083/jcb.201201133