Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Philippe Métellus"'
Autor:
Philippe Metellus, Clara Camilla, Emilie Bialecki, Nathalie Beaufils, Christine Vellutini, Eric Pellegrino, Pascale Tomasini, Manmeet S. Ahluwalia, Alireza Mansouri, Isabelle Nanni, L’Houcine Ouafik
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundOncogenic fusions of neurotrophic receptor tyrosine kinase NTRK1, NTRK2, or NTRK3 genes have been found in different types of solid tumors. The treatment of patients with TRK fusion cancer with a first-generation TRK inhibitor (such as laro
Externí odkaz:
https://doaj.org/article/ed3fc3c4abd840519e77be3825438190
Autor:
Konstantinos Gousias, Jiri Bartek, Jr., Michaël Bruneau, Emrah Celtikci, Nicolas Foroglou, Christian F. Freyschlag, Rachel Grossman, Christin Jungk, Philippe Metellus, David Netuka, Radoslaw Rola, Phillippe Schucht, Christian Senft, Francesco Signorelli, Arnaud J.P. E. Vincent, Matthias Simon
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 101950- (2023)
Externí odkaz:
https://doaj.org/article/39dbc9d99004409c8aa0fb8fcbc0348e
Autor:
Eric Pellegrino, Coralie Jacques, Nathalie Beaufils, Isabelle Nanni, Antoine Carlioz, Philippe Metellus, L’Houcine Ouafik
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Since 2017, we have used IonTorrent NGS platform in our hospital to diagnose and treat cancer. Analyzing variants at each run requires considerable time, and we are still struggling with some variants that appear correct on the metrics at fi
Externí odkaz:
https://doaj.org/article/f2cc208aa9504b5da4bddc6b83fc1c28
Autor:
Romain Sigaud, Nadège Dussault, Caroline Berenguer-Daizé, Christine Vellutini, Zohra Benyahia, Mylène Cayol, Fabrice Parat, Kamel Mabrouk, Ramiro Vázquez, Maria E. Riveiro, Philippe Metellus, L’Houcine Ouafik
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
VE-cadherin is an essential adhesion molecule in endothelial adherens junctions, and the integrity of these complexes is thought to be regulated by VE-cadherin tyrosine phosphorylation. We have previously shown that adrenomedullin (AM) blockade corre
Externí odkaz:
https://doaj.org/article/213926a4514e458da5ff6110a8a97da0
Autor:
Brunilde Gril, Anurag N. Paranjape, Stephan Woditschka, Emily Hua, Emma L. Dolan, Jeffrey Hanson, Xiaolin Wu, Wojciech Kloc, Ewa Izycka-Swieszewska, Renata Duchnowska, Rafał Pęksa, Wojciech Biernat, Jacek Jassem, Naema Nayyar, Priscilla K. Brastianos, O. Morgan Hall, Cody J. Peer, William D. Figg, Gary T. Pauly, Christina Robinson, Simone Difilippantonio, Emilie Bialecki, Philippe Metellus, Joel P. Schneider, Patricia S. Steeg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
When brain metastases form, the blood–brain barrier morphs into the blood–tumor barrier (BTB), surrounded by neuroinflammatory response. Here, the authors show that S1P3 is upregulated in neuroinflammatory response in highly BTB permeable lesions
Externí odkaz:
https://doaj.org/article/69cb9612d00a46d3a48171a71ecd0d7b
Autor:
Agnes V. Tallet, David Azria, Emilie Le Rhun, Fabrice Barlesi, Antoine F. Carpentier, Antony Gonçalves, Sophie Taillibert, Frédéric Dhermain, Jean-Philippe Spano, Philippe Metellus
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 5, Pp 8138-8152 (2014)
Breast cancer is the second most common cause of brain metastases and deserves particular attention in relation to current prolonged survival of patients with metastatic disease. Advances in both systemic therapies and brain local treatments (surgery
Externí odkaz:
https://doaj.org/article/5987c9c14a5946f38a036e3a7a2ad0cc
Autor:
Choukri Mekkaoui, Philippe Metellus, William J Kostis, Roberto Martuzzi, Fabricio R Pereira, Jean-Paul Beregi, Timothy G Reese, Todd R Constable, Marcel P Jackowski
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146693 (2016)
PurposeDiffusion Tensor Imaging (DTI) is a powerful imaging technique that has led to improvements in the diagnosis and prognosis of cerebral lesions and neurosurgical guidance for tumor resection. Traditional tensor modeling, however, has difficulti
Externí odkaz:
https://doaj.org/article/e1a36ef90f2d45959cccdbb681dbad67
Autor:
Siddharth Kharkar, Robert hernandez, Sachin Batra, Philippe Metellus, Argye Hillis, Michael A. Williams, Daniele Rigamonti
Publikováno v:
Behavioural Neurology, Vol 24, Iss 2, Pp 143-148 (2011)
Introduction: Patients with Pseudotumor Cerebri Syndrome (PTCS) may complain of difficulty in thinking or concentrating; however there has been little formal cognitive evaluation in this population.
Externí odkaz:
https://doaj.org/article/6da9211c65bb4517875b6de89690e4ff
Autor:
Pascale Tomasini, Cindy Serdjebi, Nataliya Khobta, Philippe Metellus, L’Houcine Ouafik, Isabelle Nanni, Laurent Greillier, Anderson Loundou, Frederic Fina, Celine Mascaux, Fabrice Barlesi
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 12, p 2132 (2016)
Background: Lung cancer is the leading cause of brain metastases (BM). The identification of driver oncogenes and matched targeted therapies has improved outcome in non-small cell lung cancer (NSCLC) patients; however, a better understanding of BM mo
Externí odkaz:
https://doaj.org/article/1ce76f12e8b04a42ba1a62bc9d5948af
Autor:
François Bertucci, Corinne Bouvier-Labit, Pascal Finetti, Philippe Metellus, José Adelaide, Karima Mokhtari, Dominique Figarella-Branger, Anne-Valérie Decouvelaere, Catherine Miquel, Jean-Michel Coindre, Daniel Birnbaum
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64497 (2013)
Solitary fibrous tumors (SFTs) are rare spindle-cell tumors. Their cell-of-origin and molecular basis are poorly known. They raise several clinical problems. Differential diagnosis may be difficult, prognosis is poorly apprehended by histoclinical fe
Externí odkaz:
https://doaj.org/article/6b307f7c3b1b48e489d62b90fa0e6617