Nuclear localization of glutamate-cysteine ligase is associated with proliferation in head and neck squamous cell carcinoma

Autor: Isabelle Bar, Dany Brohée, Vincent Nuyens, Luc Vanhamm, Pierrick Uzureau, Didier Dequanter, Philippe Lothaire, Karim Zouaoui Boudjeltia, Paul Delrée, Michel Vanhaeverbeek, Nathalie Nagy, Alexandre Rousseau, Maureen Van de Velde

Publikováno v: Oncology Letters, 11 (6
Oncology Letters

Glutathione (GSH) is the keystone of the cellular response toward oxidative stress. Elevated GSH content correlates with increased resistance to chemotherapy and radiotherapy of head and neck (HN) tumors. The purpose of the present cross-sectional st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcce9a0926349ddc9512a2fdf723387f
https://doi.org/10.3892/ol.2016.4458

Prognostic value of lymph node ratio for locoregional failure in patients with advanced head and neck cancers

Autor: Didier, Dequanter, Karim, Zouaoui Boudjeltia, Mohammad, Shahla, Christine, Aubert, Philippe, Lothaire

Publikováno v: Minerva stomatologica. 65(1)

In the current study, the utility of lymph node ratio (LNR) was evaluated as an alternative method for predicting locoregional failure in patients with advanced head and neck cancer.Fifty-six patients with oral and (pharyngo)laryngeal squamous cell c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e81d69dffa3ec44113c43b7a02394543
https://pubmed.ncbi.nlm.nih.gov/26862695

Sentinel node in oral cancer: the nuclear medicine aspects. a survey from the sentinel European node trial

Autor: Vivi Bakholdt, Jens Ahm Sørensen, Didier Dequanter, Isabel Sassoon, Stephan K. Haerle, Lars Sebbesen, Gerhard F. Huber, Giles Dolivet, Benjamin Gurney, Patrick M. Colletti, Mark McGurk, Julio Alvarez Amezaga, Sandro J. Stoeckli, Pedro M. Villarreal, Clare Schilling, Geke B. Flach, Martina A. Broglie, M.G. Vigili, Luis Barbier, Davide Donner, Annelise l. Krogdah, Edward Odell, Anders Bilde, Enrico Sesenna, Joseba Santamaria-Zuazua, Domenico Rubello, Enrico Maria Silini, Emma Bragantini, Luis Manuel Junquera Gutiérrez, A. Moreira, Tito Poli, Christian von Buchwald, Manuel Florentino Fresno Forcelledo, Remco de Bree, Philippe Lothaire, Marie-Cécile Nollevaux, Michael O'Doherty, Girolamo Tartaglione, Siavash Rahimi, Manuel Jácome, Agnès Leroux, Georges Lawson, Cesare Grandi, Romina Mastronicola, Philip Sloan, Elisabeth Bloemena

Publikováno v: Clinical nuclear medicine, 41(7), 534-542. Lippincott Williams & Wilkins
Clinical Nuclear Medicine
Clinical Nuclear Medicine, Lippincott, Williams & Wilkins, 2016, 41 (7), pp.534-542. ⟨10.1097/RLU.0000000000001241⟩
Clinical Nuclear Medicine, 41(7), 534-542. Lippincott Williams and Wilkins
Tartaglione, G, Stoeckli, S J, de Bree, R, Schilling, C, Flach, G B, Bakholdt, V, Sorensen, J A, Bilde, A, von Buchwald, C, Lawson, G, Dequanter, D, Villarreal, P M, Forcelledo, M F F, Amezaga, J A, Moreira, A, Poli, T, Grandi, C, Vigili, M G, O'Doherty, M, Donner, D, Bloemena, E, Rahimi, S, Gurney, B, Haerle, S K, Broglie, M A, Huber, G F, Krogdah, A L, Sebbesen, L R, Odell, E, Junquera Gutierrez, L M, Barbier, L, Santamara-Zuazua, J, Jacome, M, Nollevaux, M-C, Bragantini, E, Lothaire, P, Silini, E M, Sesenna, E, Dolivet, G, Mastronicola, R, Leroux, A, Sassoon, I, Sloan, P, Colletti, P M, Rubello, D & McGurk, M 2016, ' Sentinel Node in Oral Cancer : The Nuclear Medicine Aspects. A Survey from the Sentinel European Node Trial ', Clinical Nuclear Medicine, vol. 41, no. 7, pp. 534-542 . https://doi.org/10.1097/RLU.0000000000001241
Tartaglione, G, Stoeckli, S J, de Bree, R, Schilling, C, Flach, G B, Bakholdt, V, Sorensen, J A, Bilde, A, von Buchwald, C, Lawson, G, Dequanter, D, Villarreal, P M, Fresno Forcelledo, M F, Alvarez Amezaga, J, Moreira, A, Poli, T, Grandi, C, Vigili, M G, O'Doherty, M, Donner, D, Bloemena, E, Rahimi, S, Gurney, B, Haerle, S K, Broglie, M A, Huber, G F, Krogdah, A L, Sebbesen, L R, Odell, E, Junquera Gutierrez, L M, Barbier, L, Santamaria-Zuazua, J, Jacome, M, Nollevaux, M-C, Bragantini, E, Lothaire, P, Silini, E M, Sesenna, E, Dolivet, G, Mastronicola, R, Leroux, A, Sassoon, I, Sloan, P, Colletti, P M, Rubello, D & McGurk, M 2016, ' Sentinel Node in Oral Cancer The Nuclear Medicine Aspects. A Survey from the Sentinel European Node Trial ', Clinical Nuclear Medicine, vol. 41, no. 7, pp. 534-542 . https://doi.org/10.1097/RLU.0000000000001241
Tartaglione, G, Stoeckli, S J, de Bree, R, Schilling, C, Flach, G B, Bakholdt, V, Sorensen, J A, Bilde, A, von Buchwald, C, Lawson, G, Dequanter, D, Villareal, P M, Forcelledo, M F F, Amézaga, J A, Moreira, A, Poli, T, Grandi, C, Vigli, M G, O'Doherty, M, Donner, D, Bloemena, E, Rahimi, S, Gurney, B, Haerle, S K, Broglie, M A, Huber, G F, Krogdah, A L, Sebbesen, L R, Odell, E, Junquera Gutierrez, L M J, Barbier, L, Santamaria-Zuazua, J, Jacome, M, Nollevaux, M C, Bragantini, E, Lothaire, P, Silini, E M, Sesenna, E, Dolivet, G, Mastronicola, R, Leroux, A, Sassoon, I, Sloan, P, Colletti, P M, Rubello, D & McGurk, M 2016, ' Sentinel node in oral cancer : the nuclear medicine aspects. a survey from the sentinel European node trial ', Clinical Nuclear Medicine, vol. 41, no. 7, pp. 534-542 . https://doi.org/10.1097/RLU.0000000000001241

PURPOSE: Nuclear imaging plays a crucial role in lymphatic mapping of oral cancer. This evaluation represents a subanalysis of the original multicenter SENT trial data set, involving 434 patients with T1-T2, N0, and M0 oral squamous cell carcinoma. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bc14cedc49b69685fbc966db6a88e4
https://dare.uva.nl/personal/pure/en/publications/sentinel-node-in-oral-cancer(569daa66-65a9-4a68-8511-a53550031835).html

Sentinel European Node Trial (SENT): 3-year results of sentinel node biopsy in oral cancer

Autor: Siavash Rahimi, Giles Dolivet, Lars Sebbesen, Benjamin Gurney, Julio Alvarez Amezaga, Martina A. Broglie, Cesare Grandi, Davide Donner, Vivi Bakholdt, Pedro M. Villarreal, Anders Bilde, Philippe Lothaire, Stephan K. Haerle, Tito Poli, Emma Bragantini, Luis Manuel Junquera Gutiérrez, Manuel Florentino Fresno Forcelledo, Remco de Bree, Jens Ahm Sørensen, Isabel Sassoon, Erinco Sesenna, Romina Mastronicola, M.G. Vigili, Sandro J. Stoeckli, Manuel Jácome, Michael O'Doherty, Clare Schilling, Edward Odell, Philip Sloan, Gerhard F. Huber, Mark McGurk, Georges Lawson, Enrico Maria Silini, Agnès Leroux, Joseba Santamaria-Zuazua, Elisabeth Bloemena, Didier Dequanter, Géke B. Flach, A. Moreira, Luis Barbier, Annelise Krogdahl, Christian von Buchwald, Marie-Cécile Nollevaux, Girolamo Tartaglione

Publikováno v: European Journal of Cancer, 51(18), 2777-2784. Elsevier
European Journal of Cancer, 51(18), 2777-2784. Pergamon
Schilling, C, Stoeckli, S J, Haerle, S K, Broglie, M A, Huber, G F, Sørensen, J A, Bakholdt, V, Krogdahl, A, von Buchwald, C, Bilde, A, Sebbesen, L R, Odell, E, Gurney, B, O'Doherty, M, de Bree, R, Bloemena, E, Flach, G B, Villarreal, P M, Forcelledo, M F F, Gutierrez, L M J, Amezaga, J A, Barbier, L, Santamaria-Zuazua, J, Moreira, A, Jacome, M, Vigili, M G, Rahimi, S, Tartaglione, G, Lawson, G, Nollevaux, M C, Grandi, C, Donner, D, Bragantini, E, Dequanter, D, Lothaire, P, Poli, T, Silini, E M, Sesenna, E, Dolivet, G, Mastronicola, R, Leroux, A, Sassoon, I, Sloan, P & McGurk, M 2015, ' Sentinel European Node Trial (SENT) : 3-year results of sentinel node biopsy in oral cancer ', European Journal of Cancer, vol. 51, no. 18, pp. 2777-2784 . https://doi.org/10.1016/j.ejca.2015.08.023
European Journal of Cancer, 51(18), 2777-2784. Elsevier Limited
Schilling, C, Stoeckli, S J, Haerle, S K, Broglie, M A, Huber, G F, Sorensen, J A, Bakholdt, V, Krogdahl, A, von Buchwald, C, Bilde, A, Sebbesen, L R, Odell, E, Gurney, B, O'Doherty, M, de Bree, R, Bloemena, E, Flach, G B, Villarreal, P M, Forcelledo, M F F, Gutierrez, L M J, Amezaga, J A, Barbier, L, Santamaria-Zuazua, J, Moreira, A, Jacome, M, Vigili, M G, Rahimi, S, Tartaglione, G, Lawson, G, Nollevaux, M C, Grandi, C, Donner, D, Bragantini, E, Dequanter, D, Lothaire, P, Poli, T, Silini, E M, Sesenna, E, Dolivet, G, Mastronicola, R, Leroux, A, Sassoon, I, Sloan, P & McGurk, M 2015, ' Sentinel European Node Trial (SENT): 3-year results of sentinel node biopsy in oral cancer ', European Journal of Cancer, vol. 51, no. 18, pp. 2777-2784 . https://doi.org/10.1016/j.ejca.2015.08.023
Schilling, C, Stoeckli, S J, Haerle, S K, Broglie, M A, Huber, G F, Sorensen, J A, Bakholdt, V, Kroghdal, A, von Buchwald, C, Bilde, A, Sebbesen, L R, Odell, E, Gurney, B, O'Doherty, M, de Bree, R, Bloemena, E, Flach, G B, Villareal, P M, Fresno Forcelledo, M F, Junquera Gutierrez, L M, Amézaga, J A, Barbier, L, Santamaría-Zuazua, J, Moreira, A, Jacome, M, Vigili, M G, Rahimi, S, Tartaglione, G, Lawson, G, Nollevaux, M C, Grandi, C, Donner, D, Bragantini, E, Dequanter, D, Lothaire, P, Poli, T, Silini, E M, Sesenna, E, Dolivet, G, Mastronicola, R, Leroux, A, Sassoon, I, Sloan, P & McGurk, M 2015, ' Sentinel European Node Trial (SENT): 3-year results of sentinel node biopsy in oral cancer ', European Journal of Cancer, vol. 51, no. 18, pp. 2777-2784 . https://doi.org/10.1016/j.ejca.2015.08.023

Purpose Optimum management of the N0 neck is unresolved in oral cancer. Sentinel node biopsy (SNB) can reliably detect microscopic lymph node metastasis. The object of this study was to establish whether the technique was both reliable in staging the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe8894abd86aa55184d940a115c143a
https://dare.uva.nl/personal/pure/en/publications/sentinel-european-node-trial-sent-3year-results-of-sentinel-node-biopsy-in-oral-cancer(ae964aec-e52e-4d46-b45d-ba07c0db8d46).html

Does clinical and radiological response predict complete tumor control in N2–N3 squamous cell head and neck cancer after non-operative management of the neck?

Autor: Marc Lemort, Guy Andry, Philippe Lothaire, Ahmad Awada, Thi hien Nguyen, Yassine Lalami, Didier Dequanter, Louis Vandevelde

Publikováno v: Acta Oto-Laryngologica. 126:1225-1228

CONCLUSION: A complete clinical and radiological response observed following chemotherapy and radiotherapy is not predictive of the absence of residual disease. Moreover, salvage neck surgery does not always seem to be an effective strategy. Conseque

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c4b9ffdbb6bc0498e767019f1e95c0
https://doi.org/10.1080/00016480600818088