Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Philippe Lettéron"'
Autor:
Pushpa Hegde, Emmanuel Weiss, Valérie Paradis, Jinghong Wan, Morgane Mabire, Sukriti Sukriti, Pierre-Emmanuel Rautou, Miguel Albuquerque, Olivia Picq, Abhishak Chandra Gupta, Gladys Ferrere, Hélène Gilgenkrantz, Badr Kiaf, Amine Toubal, Lucie Beaudoin, Philippe Lettéron, Richard Moreau, Agnès Lehuen, Sophie Lotersztajn
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Hepatic fibrosis represents the liver response to chronic injury and can lead to cirrhosis. Here the authors show that mucosal-associated invariant T cells mediate chronic inflammation and fibrogenesis in the liver by inducing a proinflammatory pheno
Externí odkaz:
https://doaj.org/article/68dba654aed943aea66393450ba3bbd9
Autor:
Sarah Millot, Constance Delaby, Boualem Moulouel, Thibaud Lefebvre, Nathalie Pilard, Nicolas Ducrot, Cécile Ged, Philippe Lettéron, Lucia de Franceschi, Jean Charles Deybach, Carole Beaumont, Laurent Gouya, Hubert De Verneuil, Saïd Lyoumi, Hervé Puy, Zoubida Karim
Publikováno v:
Haematologica, Vol 102, Iss 2 (2017)
Hemolysis occurring in hematologic diseases is often associated with an iron loading anemia. This iron overload is the result of a massive outflow of hemoglobin into the bloodstream, but the mechanism of hemoglobin handling has not been fully elucida
Externí odkaz:
https://doaj.org/article/aac1a1886b7c4ca28849a86641e56d33
Autor:
Florent Guérin, Mathilde Wagner, Antoine Liné, Magaly Zappa, Magali Fasseu, Valérie Paradis, Valérie Vilgrain, Bernard E Van Beers, Josette Legagneux, Richard Moreau, Philippe Lettéron
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125493 (2015)
To determine the pathogenesis of liver nodules, and lesions similar to obliterative portal venopathy, observed after portosystemic shunts or portal vein thrombosis in humans.We conducted an experimental study comparing portacaval shunt (PCS), total p
Externí odkaz:
https://doaj.org/article/030f4695ffb847e48e3ea45fc7afffde
Autor:
Konstantinos Arapis, Jean Baptiste Cavin, Laura Gillard, Françoise Cluzeaud, Philippe Lettéron, Robert Ducroc, Johanne Le Beyec, Muriel Hourseau, Anne Couvelard, Jean-Pierre Marmuse, Maude Le Gall, André Bado
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121414 (2015)
Whereas the remodeling of intestinal mucosa after bariatric surgeries has been the matter of numerous studies to our knowledge, very few reported on the remodeling of the residual gastric mucosa. In this study, we analyzed remodeling of gastric mucos
Externí odkaz:
https://doaj.org/article/1f9aa69a9f8d4f4180e640fbe9b4eb31
Autor:
Tarek Boussetta, Houssam Raad, Philippe Lettéron, Marie-Anne Gougerot-Pocidalo, Jean-Claude Marie, Fathi Driss, Jamel El-Benna
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6458 (2009)
BACKGROUND:Neutrophils play a major role in inflammation by releasing large amounts of ROS produced by NADPH-oxidase and myeloperoxidase (MPO). The proinflammatory cytokine TNFalpha primes ROS production through phosphorylation of the NADPH-oxidase s
Externí odkaz:
https://doaj.org/article/4d0940b509dc4e10a819c4768c7ce233
Autor:
Yassine Sakar, Corinne Nazaret, Philippe Lettéron, Amal Ait Omar, Mathilde Avenati, Benoît Viollet, Robert Ducroc, André Bado
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7935 (2009)
BACKGROUND AND AIMS: The small intestine is the major site of absorption of dietary sugars. The rate at which they enter and exit the intestine has a major effect on blood glucose homeostasis. In this study, we determine the effects of luminal leptin
Externí odkaz:
https://doaj.org/article/fded59a0b5504988bc2c37216dddd789
Autor:
François Blanquart, Alexandra Baron, Marie-Hélène Nicolas-Chanoine, Olivier Clermont, Sara Dion, Erick Denamur, Marion Duprilot, Philippe Lettéron, Saskia-Camille Flament-Simon
Publikováno v:
Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2020, 88 (12), ⟨10.1128/IAI.00576-20⟩
Infection and Immunity, American Society for Microbiology, 2020, 88 (12), ⟨10.1128/IAI.00576-20⟩
Escherichia coli of sequence type (ST) 131 resistant to fluoroquinolones and producer of CTX-M-15 is globally one of the major extraintestinal pathogenic E. coli (ExPEC). ST131 phylogenesis showed that multidrug-resistant ST131 strains belong to a cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195bf081568b7df0a8c079a8c44fe887
https://hal.archives-ouvertes.fr/hal-03066174/document
https://hal.archives-ouvertes.fr/hal-03066174/document
Autor:
Marion, Duprilot, Alexandra, Baron, François, Blanquart, Sara, Dion, Cassandra, Pouget, Philippe, Lettéron, Saskia-Camille, Flament-Simon, Olivier, Clermont, Erick, Denamur, Marie-Hélène, Nicolas-Chanoine
Publikováno v:
Infection and Immunity
Escherichia coli O25b:H4 sequence type 131 (ST131), which is resistant to fluoroquinolones and which is a producer of CTX-M-15, is globally one of the major extraintestinal pathogenic E. coli (ExPEC) lineages. Phylogenetic analyses showed that multid
Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver
Autor:
Jinghong Wan, Matthieu Siebert, Maude Le Gall, Pauline Le Faouder, Michael Trauner, Hervé Guillou, Richard Moreau, Sophie Lotersztajn, Matteo Tardelli, Benjamin F. Cravatt, Abdellah Mansouri, Pushpa Hegde, Arthur Brouillet, Philippe Lettéron, Aida Habib, Nathalie Pilard, Emmanuel Weiss, Morgane Mabire, Lara Ribeiro-Parenti, Dina Chokr
Publikováno v:
Gut
Gut, BMJ Publishing Group, 2019, 68 (3), pp.522-532. ⟨10.1136/gutjnl-2018-316137⟩
Gut, BMJ Publishing Group, 2019, 68 (3), pp.522-532. ⟨10.1136/gutjnl-2018-316137⟩
ObjectiveSustained inflammation originating from macrophages is a driving force of fibrosis progression and resolution. Monoacylglycerol lipase (MAGL) is the rate-limiting enzyme in the degradation of monoacylglycerols. It is a proinflammatory enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9ac4ff6a692804dc5b626a569dc7ea
https://hal.inrae.fr/hal-02963612
https://hal.inrae.fr/hal-02963612
Autor:
Sverre Sandberg, Marta Vorland, Karen Toska, Caroline Schmitt, Sylvie Simonin, Juha P. Kallio, Helene J. Bustad, Lars Skjærven, Philippe Lettéron, Aurora Martinez, Jarl Underhaug
Publikováno v:
Molecular Therapy
Molecular Therapy, Cell Press, 2019, ⟨10.1016/j.ymthe.2019.11.010⟩
Molecular Therapy, Nature Publishing Group, 2019, ⟨10.1016/j.ymthe.2019.11.010⟩
Molecular Therapy, Cell Press, 2019, ⟨10.1016/j.ymthe.2019.11.010⟩
Molecular Therapy, Nature Publishing Group, 2019, ⟨10.1016/j.ymthe.2019.11.010⟩
Mutations in hydroxymethylbilane synthase (HMBS) cause acute intermittent porphyria (AIP), an autosomal dominant disease where typically only one HMBS allele is mutated. In AIP, the accumulation of porphyrin precursors triggers life-threatening neuro