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Autor:
Philippe J.-P. Guillaume, Marie-Luce Rosseels, Diels J. van den Dobbelsteen, Annie Delaunois, Etienne Hanon, Frederic Martin
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 67(3)
Hydroxypropyl-β-cyclodextrin (HPβCD) is a complexation agent used to enhance drug solubilization and formulation stability. Although its toxicity is well characterized, its cardiovascular effects are less known. To investigate them, HPβCD was infu