Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Philippe H. Kahn"'
Autor:
Krystel, El Hage, Giovanni, Ribaudo, Louis, Lagardère, Alberto, Ongaro, Philippe H, Kahn, Luc, Demange, Jean-Philip, Piquemal, Giuseppe, Zagotto, Nohad, Gresh
Publikováno v:
Journal of chemical information and modeling. 62(24)
GC-rich sequences are recurring motifs in oncogenes and retroviruses and could be targeted by noncovalent major-groove therapeutic ligands. We considered the palindromic sequence d(G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c74b4f59a98b9a603af159c2faddd87c
https://pubmed.ncbi.nlm.nih.gov/35895094
https://pubmed.ncbi.nlm.nih.gov/35895094
Autor:
Krystel El Hage, Giovanni Ribaudo, Louis Lagardère, Alberto Ongaro, Philippe H. Kahn, Luc Demange, Jean-Philip Piquemal, Giuseppe Zagotto, Nohad Gresh
Publikováno v:
Journal of Chemical Information and Modeling
Journal of Chemical Information and Modeling, 2022, 62 (24), pp.6649-6666. ⟨10.1021/acs.jcim.2c00337⟩
Journal of Chemical Information and Modeling, 2022, 62 (24), pp.6649-6666. ⟨10.1021/acs.jcim.2c00337⟩
International audience; GC-rich sequences are recurring motifs in oncogenes and retroviruses, and could be targeted by non-covalent major-groove therapeutic ligands. We considered the palindromic sequence d(G1G2C3G4C5C6)2, and designed several oligop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e906c9d976aa0d537451c2b4ce24a327
https://hal.science/hal-03624169
https://hal.science/hal-03624169
Publikováno v:
Biochemistry. 43:1736-1745
The kinetics and thermodynamics of the interactions of transferrin receptor 1 with holotransferrin and apotransferrin in neutral and mildly acidic media are investigated at 37 degrees C in the presence of CHAPS micelles. Receptor 1 interacts with CHA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0e79f0c796a1a9253832088bde79f2
https://doi.org/10.1021/bi030142g
https://doi.org/10.1021/bi030142g
Publikováno v:
Biochemistry. 42:3120-3130
The kinetics and thermodynamics of Al(III) exchange between aluminum citrate (AlL) and human serum transferrin were investigated in the 7.2-8.9 pH range. The C-site of human serum apotransferrin in interaction with bicarbonate removes Al(III) from Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60720edfc0216ea6fffbb12f1e7eb18f
https://doi.org/10.1021/bi020627p
https://doi.org/10.1021/bi020627p
Autor:
Nohad Gresh, Philippe H. Kahn
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 8:827-846
The hexanucleotide d(GGCGCC)2 is encountered in recurrent fashion within transcriptional activating sequences in retroviruses and protooncogenes. Our first theoretical design of novel oligopeptide derivatives of mitoxantrone, MTX (1), had enabled us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81526cf32c65b30af4ea74b1fd8625ba
https://doi.org/10.1080/07391102.1991.10507848
https://doi.org/10.1080/07391102.1991.10507848
Autor:
Nohad Gresh, Philippe H. Kahn
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 7:1141-1160
Mitoxantrone (MTX) is a recently synthesized antitumor intercalative molecule, currently in use in chemotherapy. Previous theoretical computations showed that the base pair selectivity of MTX is limited to the sole two base-pair sequence making up th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5232826985a0d8fce0e683289663d37
https://doi.org/10.1080/07391102.1990.10508552
https://doi.org/10.1080/07391102.1990.10508552
Publikováno v:
Biochemistry. 43(46)
The kinetics and thermodynamics of Bi(III) exchange between bismuth mononitrilotriacetate (BiL) and human serum transferrin as well as those of the interaction between bismuth-loaded transferrin and transferrin receptor 1 (TFR) were investigated at p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2e8695e9025db0176a4eff12c86f27
https://pubmed.ncbi.nlm.nih.gov/15544343
https://pubmed.ncbi.nlm.nih.gov/15544343