Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Philippe Guégan"'
Autor:
Léa Chazot-Franguiadakis, Joelle Eid, Gwendoline Delecourt, Pauline J. Kolbeck, Saskia Brugère, Bastien Molcrette, Marius Socol, Marylène Mougel, Anna Salvetti, Vincent Démery, Jean-Christophe Lacroix, Véronique Bennevault, Philippe Guégan, Martin Castelnovo, Fabien Montel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Viruses have remarkable physical properties and complex interactions with their environment. However, their aggregation in confined spaces remains unexplored, although this phenomenon is of paramount importance for understanding viral infect
Externí odkaz:
https://doaj.org/article/a45134be978a44bcacdb795ed89ac8b9
Autor:
Yann T. Le Guen, Chantal Pichon, Philippe Guégan, Kévin Pluchon, Tanguy Haute, Sandrine Quemener, Juliette Ropars, Patrick Midoux, Tony Le Gall, Tristan Montier
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 477-486 (2021)
An important bottleneck for non-viral gene transfer commonly relates to translocation of nucleic acids into the nuclear compartment of target cells. So-called 3NFs are optimized short nucleotide sequences able to interact with the transcription facto
Externí odkaz:
https://doaj.org/article/cbbf416e03b24cf5ad0af59a2047b63f
Autor:
Pauline J. Kolbeck, Dihia Benaoudia, Léa Chazot-Franguiadakis, Gwendoline Delecourt, Jérôme Mathé, Sha Li, Romeo Bonnet, Pascal Martin, Jan Lipfert, Anna Salvetti, Mordjane Boukhet, Véronique Bennevault, Jean-Christophe Lacroix, Philippe Guégan, Fabien Montel
Publikováno v:
Nano Letters
Nano Letters, 2023, 23 (11), pp.4862-4869. ⟨10.1021/acs.nanolett.3c00438⟩
Nano Letters, 2023, 23 (11), pp.4862-4869. ⟨10.1021/acs.nanolett.3c00438⟩
International audience; Mimicking and extending the gating properties of biological pores is of paramount interest for the fabrication of membranes that could be used in filtration or drug processing. Here, we build a selective and switchable nanopor
Publikováno v:
Macromolecules. 55:5430-5440
Autor:
Antoine Italiano, Anne Floquet, Isabelle Ray-Coquard, Jean-Yves Blay, Sabrina Croce, Raul Perret, Simone Mathoulin-Pelissier, Sophie Cousin, Jean-Philippe Guégan, Sabrina Albert, Marina Pulido, Emilie Toulza, Michèle Kind, Alban Bessede, Camille Chakiba, Antoine Giraud, Mehdi Brahmi, Maud Toulmonde
Supplementary Figure from Trabectedin plus Durvalumab in Patients with Advanced Pretreated Soft Tissue Sarcoma and Ovarian Carcinoma (TRAMUNE): An Open-Label, Multicenter Phase Ib Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b2b857fc647682e25a1a5448740d68
https://doi.org/10.1158/1078-0432.22483854
https://doi.org/10.1158/1078-0432.22483854
Autor:
Antoine Italiano, Anne Floquet, Isabelle Ray-Coquard, Jean-Yves Blay, Sabrina Croce, Raul Perret, Simone Mathoulin-Pelissier, Sophie Cousin, Jean-Philippe Guégan, Sabrina Albert, Marina Pulido, Emilie Toulza, Michèle Kind, Alban Bessede, Camille Chakiba, Antoine Giraud, Mehdi Brahmi, Maud Toulmonde
Supplementary Table from Trabectedin plus Durvalumab in Patients with Advanced Pretreated Soft Tissue Sarcoma and Ovarian Carcinoma (TRAMUNE): An Open-Label, Multicenter Phase Ib Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af37ad46e4bf2f451ab07cce104b6bc
https://doi.org/10.1158/1078-0432.22483842
https://doi.org/10.1158/1078-0432.22483842
Autor:
Antoine Italiano, Anne Floquet, Isabelle Ray-Coquard, Jean-Yves Blay, Sabrina Croce, Raul Perret, Simone Mathoulin-Pelissier, Sophie Cousin, Jean-Philippe Guégan, Sabrina Albert, Marina Pulido, Emilie Toulza, Michèle Kind, Alban Bessede, Camille Chakiba, Antoine Giraud, Mehdi Brahmi, Maud Toulmonde
Supplementary Data from Trabectedin plus Durvalumab in Patients with Advanced Pretreated Soft Tissue Sarcoma and Ovarian Carcinoma (TRAMUNE): An Open-Label, Multicenter Phase Ib Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a99940990a063176e5e2dc3cbc595f9
https://doi.org/10.1158/1078-0432.22483860.v1
https://doi.org/10.1158/1078-0432.22483860.v1
Autor:
Antoine Italiano, Anne Floquet, Isabelle Ray-Coquard, Jean-Yves Blay, Sabrina Croce, Raul Perret, Simone Mathoulin-Pelissier, Sophie Cousin, Jean-Philippe Guégan, Sabrina Albert, Marina Pulido, Emilie Toulza, Michèle Kind, Alban Bessede, Camille Chakiba, Antoine Giraud, Mehdi Brahmi, Maud Toulmonde
Purpose:Trabectedin has shown preclinical synergy with immune checkpoint inhibitors in preclinical models.Patients and Methods:TRAMUNE is a phase Ib study investigating the combination of trabectedin with durvalumab through a dose escalation phase an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3d4def8d74446fbbe851810bc66263
https://doi.org/10.1158/1078-0432.c.6531246.v1
https://doi.org/10.1158/1078-0432.c.6531246.v1
Autor:
Antoine Italiano, Jean-Philippe Guégan, Xinwei Sher, Laura Dillon, Tamas Oravecz, Thomas Schürpf, Guy Clifton
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Gwendoline Delecourt, Laetitia Plet, Yann Le Guen, Ozgul Tezgel, Guillaume Tresset, Patrick Midoux, Tristan Montier, Véronique Bennevault, Philippe Guégan
Publikováno v:
Macromolecular bioscience.
Gene delivery is now a part of the therapeutic arsenal for vaccination and treatments of inherited or acquired diseases. Polymers represent an opportunity to develop new synthetic vectors for gene transfer, with a prerequisite of improved delivery an