Inhibition of Phytosterol Biosynthesis by Azasterols

Autor: Sylvain Darnet, Laetitia B B Martin, Pierre Mercier, Franz Bracher, Philippe Geoffroy, Hubert Schaller

Publikováno v: Molecules, Vol 25, Iss 5, p 1111 (2020)

Inhibitors of enzymes in essential cellular pathways are potent probes to decipher intricate physiological functions of biomolecules. The analysis of Arabidopsis thaliana sterol profiles upon treatment with a series of azasterols reveals a specific i

Externí odkaz: https://doaj.org/article/6db61750ea2a42ec8c64390fb9e66020

Inhibition of Phytosterol Biosynthesis by Azasterols

Autor: Laetitia B. B. Martin, Franz Bracher, Philippe Geoffroy, Pierre Mercier, Hubert Schaller, Sylvain Darnet

Publikováno v: Molecules
Molecules, MDPI, 2020, 25 (5), ⟨10.3390/molecules25051111⟩
Molecules, Vol 25, Iss 5, p 1111 (2020)
Volume 25
Issue 5

International audience; Inhibitors of enzymes in essential cellular pathways are potent probes to decipher intricate physiological functions of biomolecules. The analysis of Arabidopsis thaliana sterol profiles upon treatment with a series of azaster

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bceec96ec720a17e19bbeba052ea44
https://hal.archives-ouvertes.fr/hal-03019673/file/molecules-2020-25-01111.pdf

Concise Approach to (ent )-14 β-Hydroxysteroids through Highly Diastereo-/Enantioselective Diels-Alder Reactions

Autor: Philippe Geoffroy, Michel Miesch, Blandine Ressault, Clovis Peter

Publikováno v: Chemistry - A European Journal. 22:10808-10812

14β-Hydroxysteroids, especially 14β-hydroxyandrostane derivatives are closely related to the cardenolide skeletons. The latter were readily available through highly diastero/enantioselective Diels-Alder (DA) reactions requiring high pressure or Lew

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1840bd12e5de8344ade4e12c08ca70
https://doi.org/10.1002/chem.201601926

Vitamin D

Autor: Daniele, Silvestro, Claire, Villette, Julien, Delecolle, Carl Erik, Olsen, Mohammed Saddik, Motawia, Philippe, Geoffroy, Michel, Miesch, Poul Erik, Jensen, Dimitri, Heintz, Hubert, Schaller

Publikováno v: Scientific Reports

Vitamin D3 is a secosterol hormone critical for bone growth and calcium homeostasis, produced in vertebrate skin by photolytic conversion of the cholesterol biosynthetic intermediate provitamin D3. Insufficient levels of vitamin D3 especially in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2466f0a0a17cb6e14289ad0f0e79dae8
https://pubmed.ncbi.nlm.nih.gov/30397227

Vitamin D5 in Arabidopsis thaliana

Autor: Philippe Geoffroy, Claire Villette, Carl Erik Olsen, Dimitri Heintz, Poul Erik Jensen, Daniele Silvestro, Julien Delecolle, Michel Miesch, Hubert Schaller, Mohammed Saddik Motawia

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.16348-16348
Silvestro, D, Villette, C, Delecolle, J, Olsen, C E, Motawia, M S, Geoffroy, P, Miesch, M, Jensen, P E, Heintz, D & Schaller, H 2018, ' Vitamin D-5 in Arabidopsis thaliana ', Scientific Reports, vol. 8, 16348, pp. 1-8 . https://doi.org/10.1038/s41598-018-34775-z
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)

Vitamin D3 is a secosterol hormone critical for bone growth and calcium homeostasis, produced in vertebrate skin by photolytic conversion of the cholesterol biosynthetic intermediate provitamin D3. Insufficient levels of vitamin D3 especially in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd412c1b90bfc91a80c595e8f4427eb
https://hal.archives-ouvertes.fr/hal-02268950