Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Philippe Fretier"'
Autor:
Olivier Benveniste, Roger Le Grand, Richard Le Naour, Pascal Clayette, Dominique Dormont, Frédéric Théodoro, Philippe Fretier, Bruno Vaslin, Olivier Noack
Publikováno v:
Journal of Medical Primatology. 24:94-100
TNF secretion was explored in sera during acute SIV-infection of cynomolgus macaques. A peak of TNF was detected in sera of animals in concomitance with SIV replication. Likewise, AZT treatment delayed and reduced peaks of viral replication and TNF p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4a8a908bba69e5ad6cec5a53eb5787
https://doi.org/10.1111/j.1600-0684.1995.tb00152.x
https://doi.org/10.1111/j.1600-0684.1995.tb00152.x
Autor:
Jean Louis Imbach, Joel Oiry, Philippe Fretier, Dominique Dormont, Pascal Clayette, Jean Yves Puy, Patricia Mialocq
Publikováno v:
ChemInform. 32
I-152 is a prodrug of NAC and MEA with potent pro-GSH effects in human macrophages, astrocytes and lymphocytes. This molecule could be of interest in HIV infection in respect to its antioxidant and anti-HIV activities, but also in other diseases to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f98c6145c55c8b1e59baa3109cd68460
https://doi.org/10.1002/chin.200133226
https://doi.org/10.1002/chin.200133226
Autor:
Jean-Yves Puy, Dominique Dormont, Patricia Mialocq, Philippe Fretier, Nathalie Dereuddre-Bosquet, Pascal Clayette, Jean-Louis Imbach, Joel Oiry
Publikováno v:
Journal of medicinal chemistry. 47(7)
We synthesized a series of N-(N-acetyl-L-cysteinyl)-S-acetylcysteamine (10) analogues bearing various acyl groups on thiol cysteine or cysteamine residues, to investigate the structure-activity relationship for pro-GSH and anti-HIV properties in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e324c018504a450e940a3105935e934
https://pubmed.ncbi.nlm.nih.gov/15027871
https://pubmed.ncbi.nlm.nih.gov/15027871
Autor:
Dominique Dormont, Pascal Clayette, Philippe Fretier, Jean Louis Imbach, Jean Yves Puy, Joel Oiry, Patricia Mialocq
Publikováno v:
Bioorganicmedicinal chemistry letters. 11(9)
I-152 is a prodrug of NAC and MEA with potent pro-GSH effects in human macrophages, astrocytes and lymphocytes. This molecule could be of interest in HIV infection in respect to its antioxidant and anti-HIV activities, but also in other diseases to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2bb32e892ccb39db17a5537f91fd273
https://pubmed.ncbi.nlm.nih.gov/11354374
https://pubmed.ncbi.nlm.nih.gov/11354374
Autor:
Dominique Dormont, Nathalie Dereuddre-Bosquet, Pascal Clayette, Philippe Jaccard, Philippe Fretier, Patricia Mialocq, Joel Oiry, Jean-Yves Puy, Jean-Louis Imbach
Publikováno v:
Journal of medicinal chemistry. 42(23)
Oxidative stress and glutathione (GSH) deficit may play an important role in HIV infection pathogenesis, and oral administration of GSH-replenishing drugs such as N-acetylcysteine (NAC) and 2-oxothiazolidine-4(R)-carboxylic acid (OTC) may be associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9533ae110db0fda6c15d01673d3de4
https://pubmed.ncbi.nlm.nih.gov/10579837
https://pubmed.ncbi.nlm.nih.gov/10579837
Autor:
Olivier Benveniste, Alexandre Lebeaut, Philippe Fretier, Philippe Jaccard, Nathalie Dereuddre-Bosquet, Dominique Dormont, Pascal Clayette, Bruno Vaslin, Marc Martin
Publikováno v:
AIDS research and human retroviruses. 13(11)
Interleukin 10 is a pleiotropic cytokine that is overexpressed in HIV-infected patients. Here, we investigated IL-10 expression in primary cultures of monocyte-derived macrophages (MDMs) in response to in vitro infection by HIV-1/Ba-L or two macropha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0b7185cc7c2e7cdc9e888a5f36a74f
https://pubmed.ncbi.nlm.nih.gov/9223412
https://pubmed.ncbi.nlm.nih.gov/9223412
Autor:
Pierre Fouchet, Roger Le Grand, Valérie Omessa, François D. Boussin, Dominique Dormont, Bruno Vaslin, Philippe Fretier, Frédéric Théodoro, Pascal Clayette, Olivier Benveniste
Publikováno v:
Scopus-Elsevier
HIV infection ultimately leads to AIDS, despite the immune responses elicited soon after infection. In addition to the observed changes in lymphoid cell subsets, alteration of the cytokine network most likely accompanies and/or contributes to the lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1ba5f9f2ba735b534151e3a6a0b452
http://www.scopus.com/inward/record.url?eid=2-s2.0-0030058027&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0030058027&partnerID=MN8TOARS
